Alex Monell

28 posts

Alex Monell

@almonell

Bioinformatics PhD Student at UC San Diego @GoldrathLab @yeo_lab

San Diego Katılım Ağustos 2022

153 Takip Edilen70 Takipçiler

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Alex Monell@almonell·24 Oca

We studied antigen-specific CD8 T cells in the mouse small intestine with spatial transcriptomics out @Nature! You can find the paper here (bit.ly/42mAwDS) and Max's (bit.ly/3Q9dfOB) and Miguel's (bit.ly/3E8slRA) Bluesky threads on our work.

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Journal of Experimental Medicine@JExpMed·22 Oca

Ferry, @AGoldrath et al. @ucsdbiosciences show that differentiation of tissue-resident memory T cells (TRM) is accompanied by the upregulation of the conventional DC1 (cDC1) chemoattractant, Xcl1. hubs.la/Q033wDGh0 #MucosalImmunology #TumorImmunology

Journal of Experimental Medicine tweet media

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Alex Monell@almonell·24 Oca

Thanks to the whole team on this project @reinacampos.bsky.social @heeg.io (Bluesky) @GoldrathLab @UCSDChangLab @yeo_lab @10xGenomics and @vizgen_inc for their spatial transcriptomics technologies And @elnlnx for the amazing cover art

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Alex Monell@almonell·24 Oca

Some press releases from: UCSD: bit.ly/4aspGOJ Allen Institute: alleninstitute.org/news/new-resea… LJI: bit.ly/40MjDBe @ljiresearch @AllenInstitute @UCSDHealthSci

Alex Monell@almonell·24 Oca

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Alex Monell@almonell·9 Oca

Check out the published version of our paper!

Tatsuya Nobori@nobolly

New year, new paper! Now published in @Nature. We identified and characterised diverse immune cell states in plants under pathogen attack. My postdoc work in @JoeEcker lab at @salkinstitute. nature.com/articles/s4158…

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Alex Monell@almonell·2 Nis

Check out Bento, a toolkit for studying sub cellular transcript localization in spatial transcriptomics data led by @mah_clarence @NoorsherAhmed

Gene Yeo’s Lab at UC San Diego@yeo_lab

Excited to share research from @mah_clarence and @NoorsherAhmed in my group to enable deeper analysis of subcellular RNA localization from spatial transcriptomics datasets. link.springer.com/article/10.118…

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Alex Monell@almonell·26 Mar

We're excited to receive feedback from the community for this big team effort! biorxiv.org/content/10.110…

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Alex Monell@almonell·26 Mar

Finally, we performed spatial on human terminal ileum samples to draw relevant parallels to our mouse findings.

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Alex Monell@almonell·26 Mar

Our team (@MReinaCampos @MaximilianHeeg @GoldrathLab @UCSDChangLab @yeo_lab) used single-cell spatial transcriptomics to study antigen-specific Cd8 T-Cell (P14) responses to acute systemic viral infection in the small intestine. Check it out on biorxiv! biorxiv.org/content/10.110…

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Miguel Reina-Campos@MReinaCampos·26 Mar

How is immunity molded by the tissues it inhabits? Excited to share the latest @GoldrathLab study - a “TRM exposé” - in which we found that CD8 T cell location and functional states are fundamentally intertwined.biorxiv.org/content/10.110…

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Alex Monell@almonell·14 Mar

Check out our recently published work building a spatial atlas of fetal heart development 🫀

nature@Nature

Nature research paper: Spatially organized cellular communities form the developing human heart go.nature.com/48Tw92N

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Nature Biotechnology@NatureBiotech·9 Mar

AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight science.org/doi/10.1126/sc…

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Miguel Reina-Campos@MReinaCampos·3 Mar

Curious about the Reina Lab? Functional genetic screens, metabolomics, and lots of #spatialtranscriptomics to define the inner workings of T cell tissue immunity in infection and cancer -> lji.org/labs/reina-lab/

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Tatsuya Nobori@nobolly·12 Haz

Our PHYTOMap paper (w/ @JoeEcker @ry_lister @molivarina) has now been published in @NaturePlants 🌱🧬🔬 Multiplexed single-cell 3D spatial gene expression analysis in plant tissue using PHYTOMap nature.com/articles/s4147…

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Alex Monell@almonell·15 May

Well deserved, congrats!

Tatsuya Nobori@nobolly

Thrilled to share that I will be opening a lab @TheSainsburyLab next year! My lab will study plant-microbe interactions with cutting-edge technologies that bring genomics and cell biology together. I will post updates on available positions on Twitter. Stay tuned!

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Luca Marconato@LucaMarconato2·10 May

1/9 Excited to share #SpatiaData, a framework for representing spatially-resolved omics technologies. Great colab w/ @g_palla1 @ky396 @ivirshup @HeidariElyas @TreisTim Marcella @rahulbshrestha @harald_voeh @wolfgangkhuber @MoritzGerstung @notjustmoore @fabian_theis @OliverStegle

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Keşfet

@AGoldrath @ucsdbiosciences @Reinacampos @Heeg @GoldrathLab @UCSDChangLab @yeo_lab @10xGenomics