Almudena Serrano-Benítez

🚨 Fully funded #PhD opportunity! 🚨 Passionate about cancer research? Join @MadziaCrossley's team to investigate how R-loop dysregulation contributes to cancer. 📍 Cambridge, UK 💰 Fully funded 📅 Apply by 24 March 2025 cruk.cam.ac.uk/vacancies/phd-…

Happy to share our newly published article in Nature Communications! In this work, we uncover the novel role of KLF5 in sensitizing cells to ATR inhibition, identifying it as a synthetic lethal partner with the tumor suppressor ARID1A. @SPJacksonGroup nature.com/articles/s4146…

Now out in @GenomeMedicine @BioMedCentral. Transform your #crispr screens with "Exorcise", EXOme-guided Re-annotation of nuCleotIde SEquences, doi.org/10.1186/s13073….

Genome engineering excelled at small nucleotide changes, but large edits remained challenging. Recent innovations are changing this. We reviewed the field of structural variant engineering @NatureGenet 🧬 @JulianeWeller @TVanderstichele @LeopoldParts nature.com/articles/s4158…

Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells cell.com/cell/fulltext/…

#LateXou "Un país sin poesía y sin ciencia es un país en el que vivir resulta mucho más incómodo" 📙 Marc Giró reivindica al poeta valenciano Vicent Andrés Estellés

las temporeras y temporeros de huelva también necesitan ayuda. sus chabolas se han destrozado

Always a treat to catch up with @SPJacksonGroup alumni. And an opportunity to hear about the latest breakthroughs in the DDR field @EMBO meeting, #EMBOdnaDamage24

Epitranscriptome in action: RNA modifications in the DNA damage response: Molecular Cell cell.com/molecular-cell…

Thrilled to see our work on murine oesophageal #Epithelioids published in @NatureGenet, after many years of hard work alongside @AlbertHerms during our postdoc at Phil Jones' lab @Sangerinstitute and built on the foundational work by @MariaPAlcolea nature.com/articles/s4158…

The @duxin_lab , with @NilssonLabCph, uncover #PolK's dual roles in #DNAdamage bypass. Using #CRISPR & #Xenopuseggextracts, they show PolK’s catalytic & non-catalytic functions -repairing minor groove lesions and aiding Polζ in overcoming #chemotherapeutic-induced DNA lesions!⬇️

Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors! science.org/doi/10.1126/sc…

Our latest paper -> On identifying the mutations driving clonal hematopoiesis using machine learning models - BoostDM-CH Great team work by @SantiDemajo, @JoanEenric, @fmuinos et al Tweetorial 👇

Excited to share our new preprint, led by our @GiuseppinaDAle9 and Olga Kochenova @harvardmed, a great collaborative effort with Johannes Walter's lab, + @GS_Lab_Bham. USP37 prevents premature disassembly of stressed replisomes by TRAIP biorxiv.org/content/10.110…

Thrilled to share my lab’s latest work, out recently in Mol Cell, on a role for HLTF in G4 resolution. Led by the amazing Gongshi Bai with essential contributions from @davidcortez, Brandt Eichman, @CejkaLab and @BoultonLab. See: authors.elsevier.com/a/1jbBg3vVUPRm…

Excited to share our lab's latest research, out today @NatureSMB, which describes how 53BP1 controls DNA Repair in class-switching B cells & BRCA1 mutant cancers. Final article can be found here: nature.com/articles/s4159…; & the following thread walks you through the details

Many thanks to the @MRC_LMB (the people & their science) & @UKRI_News for this amazing unbelievable opportunity. I'm ecstatic beyond measure. It's a bit intimidating to be in such a great place full of groundbreaking minds but hope I can contribute with my share to new research!

RAD51 protects abasic sites to prevent replication fork breakage dlvr.it/TCHxrp

Esto es El Congo. Esto son las minas para extraer los minerales para que occidente tenga progreso. Es una mina que ha colapsado, debido a la manera infrahumana en la que trabajan, muchos son niños. Después cuando huyen de sus países,no los quieren aquí.

Online Now: RNA interacts with topoisomerase I to adjust DNA topology dlvr.it/TCBkDV