altmeyerlab

Sharing our latest work @UZH_en tracking DNA damage inheritance by Live+QIBC nature.com/articles/s4158…. Huge congrats to @APanagopoulos_, M. Stout and all co-authors for this tour de force! Beautifully summarized by @S_J_Aitken and E. Reilly @NatureNV nature.com/articles/d4158….

Online Now: Epigenetic consequences of DNA damage dlvr.it/TQMfHf

Excited to share our new Nature study! 🧬 We (@UruciSidrit et al) discovered that CFAP20 helps clear stalled RNAPII, preventing harmful co-directional clashes with DNA replication machinery. This protects cells from R-loops and genome instability. nature.com/articles/s4158…

🚨 Exciting news! Our latest study is out in Nature Communications!
We reveal how specific BRCA2 mutations can hijack transcriptional programs—beyond their role in DNA repair.
🔗 nature.com/articles/s4146…
#CancerResearch #BRCA2 #Genomics

Our latest paper has just been published in Cell! doi.org/10.1016/j.cell… We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.

📢Please spread the word📢 Several postdoc positions (wet and computational) open in the lab to work on different research lines (see thread) We seek highly motivated candidates to join our team @CNIOStopCancer cnio.es/en/research-in… E-mail CV and brief motivation statement

A comprehensive genetic catalog of human double-strand break repair | Science science.org/doi/10.1126/sc…

Excited to share our latest research “DNA2 enables growth by restricting recombination-restarted replication” in @Nature defining DNA2’s essential function and elucidating links to primordial dwarfism and cancer. Thanks to the team and all collaborators! nature.com/articles/s4158…

📢Deadline extended! Our 2nd Spatial Genome Organisation Conference deadline has been extended to 25 Sep, dont miss out on joining our fantastic line up of speakers, alongside Karim, Matthias and Irene in what is set to be a fantastic meeting this October! #SGO25 Final slots ➡️bit.ly/3JJzYR4

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. nature.com/naturecareers/… Please repost!

Deadline approaching for our 2nd Spatial Genome Organization Conference! #SGO25 🗓 31 Oct – 03 Nov 2025 📍Riviera Maya, Mexico 👨‍🔬 👩‍🔬 🧑‍🔬 Chairs: Matthias Altmeyer @altmeyerlab , Irene Chiolo, and Karim Mekhail @KarimMekhail Join an international community of scientists uncovering the roles of nuclear and genome architecture in biology, development, aging, and disease. 🧭 Poster submission deadline: 01 Sept 2025 🧬 Registration deadline: 01 Sept 2025 📎 Details & registration: bit.ly/45Mmhtv We have a handful of $250 registration grants remaining! To claim, email amy@fusion-conferences.com with your name, position title, current research topic, and an abstract for a poster presentation.

🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods! 📦 Ultrack — robust, scalable nD cell tracking 🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration Let’s dive in! 👇 (LINKS BELOW)

Another exciting research article from a member of the #RepliFate network! The @altmeyerlab identified the CNOT1-CCR4-NOT complex as a multi-level suppressor of the 53BP1-p53-p21 signaling axis. Check out their findings here: doi.org/10.1016/j.celr…

New work from the lab: Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling @CellReports. Congratulations to first author Antonio Galarreta and to all co-authors. cell.com/cell-reports/f…. #Microscopy #RNAiScreen #Condensates

Want to better understand nuclear and genome organisation in various organisms, tissues, and cell states? Join @KarimMekhail , @altmeyerlab & Irene Chiolo at the upcoming 2nd Spatial Genome Organisation Conference this October! Talk Submission has been extended until 14th July, dont miss out! 👉bit.ly/40dMn5e #SGO25

An ingenious technique reveals how stressed cells divide to produce progeny that have different traits — a phenomenon that can initiate cancer go.nature.com/4jbI7d5

I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @ScienceMagazine ! (link at end of 🧵)

New @Nature An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer #MOESM8" target="_blank" rel="nofollow noopener">nature.com/articles/s4158…

Looking very much forward to the 2nd edition of the Fusion Conference on Spatial Genome Organisation #SGO25 @Fusion_Conf @KarimMekhail @chiolo_lab. Early bird registration closes soon: June 2nd, 2025. Slots available for selected talks from abstracts: fusion-conferences.com/conference/188

Come join us in Heidelberg to celebrate cell biology - 50 years of German Society for Cell Biology #DGZ50 Multiple topics, many excellent speakers and a great location.