
Brian O'Neill
944 posts


@TheCryptoDaddi How long did it take you to get to 4mg and where did you start from ? I started .5 on Wednesday. Wondering when to move up.
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Titrated up to 4mg of Reta today. Reading an overwhelming amount of positive reviews that say 4mg is the sweet spot for fat burning and also keeps sides away. Taking it every 6 days instead of once a week.
Feels like I’ve about got this Retatrutide protocol dialed in. Anyone else running the same or similar?
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@moncif @bryan_johnson Thanks. I've started 0.5 this week, might move to 1mg next week depending on results.
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These numbers are shocking. It's like we got a new frontier AI model but for the body.
Lilly's phase 3 results for retatrutide:
> highest dose lost 28.3% of body weight in 80 wks
> 70 lbs ave
> 45% lost 30% or more of their body weight
> 65% on the top dose no longer clinically obese
Retatrutide is more dynamic than semaglutide and tirzepatide because it targets three receptors (GIP, GLP-1, and glucagon), versus one and two, respectively.
Side effects, on the highest dose (12mg), were higher for retatrutide than tirzepatide (nausea and GI), with an 11.3% drop out rate. The lowest 4mg dose still delivered 19% loss with fewer dropouts than placebo.

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@moncif @bryan_johnson How quickly did you move up to 2mg ?
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@bryan_johnson 12mg is wild. I be on 2mg and the nonchalance is through the roof.
We need research on impact on dopamine receptors.
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Brian O'Neill retweetledi

This is why the DTCC will be a major switch for tokenization. 🎚️
Right now, issuers like Securitize and Ondo are tokenizing securities one by one.☝️
It’s slow and messy.🔻
The DTCC will do it completely differently.
Its nominee, Cede & Co., is already the registered owner for NEARLY ALL U.S. stocks.😏💨
One single move lets the DTCC onboard the ENTIRE market at once.🔑
No waiting for each issuer.
This unique capability will allow the DTCC will “leapfrog” the current slow way and jump straight to massive scale.📈
Documented.📝👇

SMQKE@SMQKEDQG
The DTCC is a major switch.🎚️💨
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Brian O'Neill retweetledi
Brian O'Neill retweetledi

🚨 CKB (Nervos Network) — Back in the Game? What’s happening right now
📊 While the market is quiet, CKB is quietly building real fundamentals:
— The project is being recognized among altcoins with strong real-world utility
— Key upgrades are being launched and tested:
• Fiber Network v0.6.0
• New block explorer
• DAO 1.1 in preparation
⚙️ The key point: Nervos isn’t chasing hype — it’s focused on Web3 infrastructure and cross-chain. This is a long-term play.
📉 Price is currently under pressure, market looks weak
BUT:
— the project keeps developing
— the ecosystem is expanding
— interest in Layer 1 + BTCFi is growing
📈 Growth potential depends on:
— DeFi & dApps launch
— developer activity growth
— cross-chain adoption
💡 Takeaway:
CKB looks like an undervalued infrastructure asset, not just another hype coin.
👉 If altseason kicks in + real use cases follow — this could move fast.
#CKB #Nervos #NervosNetwork #Crypto #Altcoins #Web3 #Layer1 #BTCFi #Blockchain #CryptoNews #Altseason #DeFi #CryptoInvesting #Undervalued #CryptoAlpha
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@The_Sycomore First pic reminds me of the greenhouse in SUNSHINE
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Brian O'Neill retweetledi

Tokenization is reshaping regulated finance by moving assets onto programmable ledgers, delivering efficiency gains but requiring strong policy and trust anchors to protect stability. Read our new IMF Note on the issue: elibrary.imf.org/view/journals/…

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Let’s just talk a wee while. Drop your favorite quote from #28YearsLater: The Bone Temple with no context.
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Brian O'Neill retweetledi
Brian O'Neill retweetledi
Brian O'Neill retweetledi
Brian O'Neill retweetledi

@RealEmirHan A great little tangent story by Quentin Tarantino as Laurence Fishburne was offered the part as Jules in Pulp Fiction as well as Die Hard III . . . which both wound up going to Samuel L Jackson
Love movie history with casting choices and dominos
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Brian O'Neill retweetledi

.@EPfestival promoter Melvin Benn says there’s no circumstances under which the mics will be cut off on @KNEECAPCEOL, as happened The Mary Wallopers last week.
“Mics won't be switched off. They've got really important messages and they didn't do anything wrong at Glastonbury.”

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@ZerpaayOfficial @daniel_wwf Sorry to poop your party but @daniel_wwf is right. Iso20022 is a messaging standard. Ripple their software is compliant with that cryptocurrency's has nothing to do with iso20022 but have fun in ur rabbithole 😁
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Brian O'Neill retweetledi

"We don’t need any more evidence, we don’t need any more proof. We know what’s happening in Gaza and those who send military aid to Israel know too.
"There will be no more Gaza soon. There will be even fewer journalists, mothers, fathers and children."
Read Aoife Moore: tinyurl.com/55n9xvfd

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Brian O'Neill retweetledi

















