Etienne

Exesmestane, Doxycicline, Doxazosin, Proviron, Epitalon + BAC Water, Pill Cutter Estrogen eliminated Circadian Rythm restored Infections dont stand a chance SHBG through floor Doxazosin for a quick experiment i wanna run 🫣🫡🤔

Why is sleeping at night so hard but sleeping in the morning is like drifting away on a soft fluffy cloud while time passes at 10x speed

I’m still surprised yohimbine isn’t more popular. There aren’t many otc fat burners that come even close to the fat loss I get from a few weeks of yohimbine before fasted cardio. If you can tolerate ephedrine alongside you’re going to have a pretty insane combo that beats any of your SLU-PP, 5-amino-1mg, or any of the research chem type stuff. They will work better COMBINED with some of said research chem stuff. But if I had to choose one or the other, give me the good ole dirty stims.

Testosterone and estradiol cause thymic atrophy, DHT preserves structure while limiting regrowth In old rats, thymus regrows after castration, but steroid exposure reverses this in a hormone-specific way. Testosterone and estradiol shrink the thymus ~50%, disrupt structure, and reduce lymphocytes. Corticosterone also lowers lymphocytes but is less potent on thymus size. Progesterone reduces thymus weight without clear lymphocyte depletion. DHT is distinct: it limits thymus regrowth but preserves normal histology and does not suppress white cell count. This separates two mechanisms: true thymic atrophy (testosterone, estradiol) vs inhibition of regeneration without structural damage (DHT). PMID: 3585226 "...The differences between the effects of the steroids were most apparent when considering the histological appearance of the thymus. In testosterone- and oestradiol-treated animals there was a severe depletion of thymic lymphocytes in the cortical region, which was narrow, and the corticomedullary junction was ill-defined (results not shown). There were areas of fatty tissue which we have always seen in age-related cases of thymic involution. In contrast, the thymus from DHT-treated animals was normal and indistinguishable from that of orchidectomized sham-treated animals or from normal young rats (results not shown);” "...The pattern of total white cell counts obtained is shown in Fig. la. In blood from testosterone-treated rats the total white cell count was significantly (P<0-01) lower than that in blood from sham-treated rats . The total white cell count was also significantly (<0 5) reduced in oestradiol- and corticosteronetreated rats , but not in rats treated with progesterone or DHT . Table 1 shows the results of the differential white cell count. From this it may be deduced that the reduction was possibly due to changes in the lymphocyte count. In all steroid-treated groups the neutrophil count was markedly increased.” "... Dihydrotestosterone is generally considered to be the potent active metabolite of testosterone, but it appeared to have no involutionary effect on the regenerating thymus , despite the reduction in weight compared with that of untreated animals. Furthermore, DHT did not reduce the total white cell count significantly . A possible explanation for the different effects of testosterone and DHT may be provided by Pearce, Khalid & Funder (1981) who injected DHT chronically into intact and orchidectomized male mice. Dihydrotestosterone had no effect on the thymus of intact mice...Testosterone markedly involutes the thymus in intact males (Selye & Albert, 1942a)."

Oh look it’s that time of the year where everyone randomly gets fixated on the Randle cycle and half of twitter get memed into separating carbs and fats with every meal