gregory hinkle

@nytopinion @ezraklein Clinton single-handedly turned the Dems from the party of New Bedford to the party of Nantucket.

On The Ezra Klein Show, Ruy Teixeira explains how the working class became alienated by elites in the Democratic Party. “They feel these elites are telling them what to think, how to think and even how to talk,” he tells @EzraKlein. Listen: nyti.ms/3OthHHs

At height of opioid crisis during my tenure as ⁦@IAmBiotech⁩ Chair, we developed industry principles to address crisis. #1 was to rally industry innovation for non-addictive new Rx. Today, we are one step closer to bringing this change for society! businesswire.com/news/home/2024…

Two for two! Congrats to the team on our second @NEJM publication demonstrating the promise of #CRISPR!

@Alnylam Responsibility matters! Way to go Alnylam.

At Alnylam, being "a responsible company" is about more than pledging to make a difference or totaling up our volunteer hours. It's about the initiatives we undertake, the community organizations we work with and the decisions we make about how we grow. It's also about living by our values in the way that we do business and the example we aim to set within our industry. We're proud to be recognized by @Newsweek for our efforts for the 2nd year in a row, being named one of America's Most Responsible Companies! Learn more: bit.ly/3t7Z0la #CorporateResponsibility #ESG #MostResponsibleCompanies

@NYTGames The bot was acting very oddly today. Saying it did the puzzle in 2 steps but showing a word procession of at least 3 guesses.

The next time you solve Wordle, you might notice that WordleBot’s recommendations have changed. The bot is wiping the SLATE clean to make way for a new starting word. nyti.ms/3HeOBaA

Biotech bound: For blue-collar apprentices, biomanufacturing can be a ticket to the middle class trib.al/o6UbCIQ

$ALNY is probably one of the most productive R&D engines in biopharma's history. Expect 15 INDs (internal and partnered programs) in 2024-25.

We love talking to students about #STEM, sparking interest in careers in #biotech! At @Nature's recent #CrackingtheCode23 @NatureConf hosted at @WPI, colleagues including our Chief DE&I Officer and former head of Regulatory, Sara Nochur met and spoke with hundreds of students from local high schools. We were thrilled by their interest and excitement and expect to see many of them become the next generation of biotech leaders!

Proud to partner with @nature on their upcoming @natureconf focusing on the development of nucleic acid medicines. Excited for three days of discussing recent clinical successes, and current and upcoming challenges in the development of nucleic acid #medicines. #CrackingTheCode23

Our event exploring recent clinical and research developments of #NucleicAcid medicines is now open! Get your tix and submit abstracts at conferences.nature.com/CrackingCode In partnership with @moderna_tx @Alnylam @WPI @UMassChan @Nature @natBME @NatureBiotech @NatImmunol @NatRevDrugDisc

Agree @VasantRJadhav! This is a remarkable clinical translation story! 1. ALN-HBV goes into clinic, shows LFT⬆️ not predicted in pre-clin studies 2. @Alnylam discovers hybridization-dependent off-targets, mediated by seed region miRNA-like effects

@thegridkid I loved the story puzzle. I told my non-daily-puzzle friends to give it a try.

So you didn’t enjoy today’s puzzle!!! That’s fair. Was never gonna be for everyone. But is it reeeeally necessary to direct awful, scathing sentiments toward Will/the constructor? We can do better, Crossworld 😇

@Freakonomics Not very

It seems as if live theater — from Broadway and the West End down to the smallest regional theaters — is undergoing massive changes, most of them bad. How interested are you in a Freakonomics Radio examination of theater economics?

@JMaraganore @US_FDA A great day for patients

Today is the 5 year anniversary of ONPATTRO’s US approval! The 1st RNAi therapeutic to reach the market and the start of MANY more RNAi medicines for patients! I’ll never forget the day and the moment when we heard from @US_FDA!

Deadline: Aug 21 Submit at: cvent.com/c/abstracts/e6… Topics: #GenomeEditing #Transcriptomeediting #DNA #RNA #ASOs #siRNAs #GeneTherapies and more @WPI @UMassChan @moderna_tx @Alnylam @NatureBiotech @natBME @NatImmunol @NatRevDrugDisc

@Freakonomics Microbreweries are ubiquitous. How did that happen? Worthy of your attention.

In the spirit of our recent series on the economics of whaling, a listener has suggested we do a series on the economic history of beer. Thumbs up or down? If up, what would you be most excited to learn, and who would you want to hear from? All story ideas welcome. Thanks!

@TamarHaspel Cable TV

Stuff Americans spend money on that's mostly useless: Dietary supplements: $35B Cough/cold medicine: $11B Bottled water: $40B Anti-aging stuff: $18B Homeopathy: $2B Chiropractors: $6B Dumb diet stuff: $30B (wild-ass guess) What am I missing?

"Cracking the Code: The Dawn of Nucleic Acid Medicines" will bring together academics in basic and translational research and their peers in thriving biotechs and promising startups to foster dialog and to spearhead collaborations. Register now: bit.ly/41ybltP

NIH funding makes papers, not drugs. Papers important, but can’t treat disease with them. Risk capital investment makes drugs. Patients need drugs.