Graham MacLeod, PhD

Don’t miss the new issue of #ScienceSignaling! New insights into Wnt signaling could inform the design of rational ligands for therapy, a Review discusses the latest discoveries about the origins of brain metastases and potential targets, and more. scim.ag/4tDltA9

Congratulations to Stephane Angers and all the hard-working teams funded by Genome Canada's Genomic Application Partnership Program! Angers will be the academic leader alongside Tracy Stone, Director of ProteinQure, in this GAPP-funded project: ontariogenomics.ca/awarded-projec…

The Donnelly Centre is looking for a new team member! We're hiring a Financial Assistant to help process a variety of activities and prepare information for budget planning and reporting. See below for more information: jobs.utoronto.ca/job/Toronto-Fi…

Science editorial: Poilievre "echoes rhetoric used by U.S. President Donald Trump’s administration to justify canceling research grants and shutting down government programs—has alarmed many researchers." science.org/content/articl…

Register for the upcoming Wnt Signaling GRC taking place June 22 – June 27, 2025, at Bates College in Lewiston, Maine, USA. The conference program, developed by conference chairs, Madelon Maurice and Ken Cadigan, highlights the cutting-edge work being conducted in the field. 1/2

🎉 Excited to share our latest work in @stemcellreports! This marks the final chapter of my postdoc in the @angerslab. cell.com/stem-cell-repo… 🧬✨ We show how individual Frizzled receptors regulate Wnt-β-catenin signaling kinetics in hPSCs, influencing mesoderm commitment🧵1/n

@BrainSurgn1989 @lincolndstein @MarioniLab @BenSimons_Lab @SpringerNature @Nature Congrats Peter and team!! Amazing work!

Read our latest #research on glioblastoma origins and growth, injury-reprogramming to neural crest-like identity, led by Akram Hamed from my lab, with @lincolndstein,@MarioniLab,@BenSimons_Lab, published with @SpringerNature in @nature, rdcu.be/d5n7I

New postdoc opportunity in multiscale mapping of human model tissue systems careers.iscb.org/jobs/view/8959 @acceleration_c @DonnellyCentre

@LindseyLabGroup @UM_RadyFHS @um_HACS_GSA @umanitoba @manitobaneuro @CAN_ACN @StemCellNetwork Congratulations on your new facility!

Thanks Global News for celebrating the Grand Opening of the new Rady Biomedical Fish Facility with us this week! @UM_RadyFHS @um_HACS_GSA @umanitoba @manitobaneuro @CAN_ACN @StemCellNetwork google.ca/url?sa=t&sourc…

For no reason in particular, I would like to remind everyone that we have a Functional Genomics faculty position opening at the @DonnellyCentre at the University of Toronto (in Canada 🇨🇦) 👀 #ASHG24 jobs.utoronto.ca/job/Toronto-As…

This is a continuation to our ongoing collaboration with @BrainSurgn1989 and also includes contributions from @DanielSchramek 's lab.

We show consistent functional differences between the "Developmental" and "Injury Response" patient-derived GSC cell lines that point to therapeutic vulnerabilities in each state.

New research from our GBM team in the @angerslab, co-led with @MolaeiFatemeh We leveraged our genome-wide CRISPR screen results and designed a focused library to dig deep into subtype-specific vulnerabilities in Glioblastoma stem cells. doi.org/10.1158/0008-5…

A team led by @UofT researchers has uncovered new targets that could be key to effectively treating #glioblastoma, a lethal type of brain #cancer. Glioblastoma is challenging to treat due to the resistance of its stem cells to therapy. Learn more 👉 uoft.me/Glioblastoma

Very cool to be featured in 'Humans of RHSE'! @RHSE_UofT @DonnellyCentre @StephAngers Read more about my postdoctoral work and beyond here: rhse.temertymedicine.utoronto.ca/news/humans-rh…

It's faculty job application season so why not apply to the University of Toronto and be my colleague at the @DonnellyCentre! We have a tenure-track opening to do functional genomics research at our world-class institute. Check it out and apply by Jan. 16! jobs.utoronto.ca/job/Toronto-As…

@iselkholi @CCSResearch @DrDrAprilRose @LDI_ILD @mcgillu Thanks!