Giovanni Aviles

Zooming around a bacteria cell. It's so cool I just got the cell imported (including lipids) and rendering correctly with the new rendering engine (it's called Angstrom). 3x performance boost! So much detail (too much?!) #screenshotsunday #gamedev #scicomm #xcode #swiftlang

~4,000 workers rallying at UC Berkeley

DELE1 oligomerization promotes integrated stress response activation Excited that we (⁦@XiaoyanGuo99⁩ ⁦@gio_av⁩) could contribute to this work led by @_JieYang ⁦@LanderLab⁩ and see the structure of our friend DELE1 for the first time! biorxiv.org/content/10.110…

Individual atoms within a protein can now be located using the technique of cryo-electron microscopy. What are the implications of this advance? go.nature.com/2HdMR6k

eIF2α controls memory consolidation via excitatory and somatostatin neurons nature.com/articles/s4158…

Interested in CRISPRi in iPSCs and derived cell types? Together with @AllenInstitute & @WardLab_NIH, we generated a highly characterized, publicly available line. Big thanks to @KunLeng2, @DraegerNina, Olivia Teter, @sydsat & others in the @kampmannlab! tinyurl.com/y6fgqvnj

Congratulations to our newest #NobelPrize laureate Jennifer Doudna. From this picture we can imagine that she was happy to find out she had been awarded this year’s Chemistry Prize!

Now online! #Ribosome collisions trigger general #stress responses to regulate #cell fate bit.ly/3gckWiJ

New Article online now at Cell: Modulation of RNA Condensation by the DEAD-Box Protein eIF4A zpr.io/tMJTE

(2/2) This is exactly why it’s essential for white/white-passing people like me to stand in solidarity with black lives matter. If you can’t protest, think of giving to an org supporting protesters, like a bail fund. (bailfunds.github.io) #BlackLivesMatter

(1/2) My sister & I are both half Puerto Rican. I’m white-passing, my sister is not. Yesterday she told our mom how she’s scared of the police bc she has kinky hair & is more melanin-gifted than me. I benefit from the same white privilege that threatens to brutalize my sister.

The Graduate and Postdoc Queer Alliance at UCSF firmly believes that Black Lives Matter and Black Trans Lives Matter. We implore the non-Black and non-trans members of GPQA to speak up and fight against these injustices. Donate to @BlackVisionsMN and let your voices be heard.

OPA1 mediates inner mitochondrial fusion and mutations cause optic atrophy. Yu et al. present the crystal structure of a minimal GTPase domain of human OPA1, which sheds light on its dimerization and provides an explanation for pathogenic mutations bit.ly/35F6xYf

“A 17-year-old whose death was linked to the novel coronavirus despite not having any previously reported health conditions was denied treatment at a California medical facility over his lack of insurance, according to the mayor.” #MedicareForAll independent.co.uk/news/world/ame…

New paper from @JSWlab: many of the small, translated open reading frames we see by ribosome profiling produce peptides with specific molecular functions in the cell. Very nice work, and I look forward to a @BerkeleyMCB talk about it in a couple of weeks. science.sciencemag.org/content/367/64…

so happy to have been part of this project! Check out our paper in @nature today!

Great commentary on both papers from @chaynes329 and Bradford Tremblay: nature.com/articles/d4158…

Two very different roles for a kinase enzyme: in DNA repair and ribosome assembly go.nature.com/392hFPL

CRISPO-Cas9 CRISPAMOS-Cas9 CRISPAS-Cas9 CRISPÁIS-Cas9 CRISPA-Cas9 CRISPAN-Cas9

The test is legendary for its toughness. But is selection by ordeal still the best way to groom competent guides? #longreads trib.al/YzS1GxM