Gregory Geisler

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Gregory Geisler

Gregory Geisler

@gregorya57

Humanist on a bike. Evidence-based worldview.

Austin, TX Katılım Şubat 2013
4.8K Takip Edilen465 Takipçiler
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Gregory Geisler
Gregory Geisler@gregorya57·
It's time. U.S. Code Title 4. FLAG AND SEAL, SEAT OF GOVERNMENT, AND THE STATES Chapter 1. THE FLAG Section 8. "The flag should never be displayed with the union down, except as a signal of dire distress in instances of extreme danger to life or property."
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Paul F. Austin
Paul F. Austin@PaulAustin3w·
Most people hear "DMT" and think aliens, machine elves, interdimensional portals. The esoteric reputation is so dominant that it overshadows something far more practical… nn-DMT might be the most effective acute treatment for the most painful condition known to medicine. Cluster headaches are called "suicide headaches" for a reason. The pain is rated worse than cancer, broken bones, and childbirth. Suicidal ideation occurs in 55% of patients. Attacks hit up to eight times a day. And for the chronic variant, there is no approved medication on the market. Psilocybin and LSD can help prevent cycles, and the data there is strong. But they have a practical limitation: onset time. If you're woken at 3am with pain boring into your eye socket, you can't wait 45 minutes for psilocybin to kick in or commit to 6 to 12 hours of altered consciousness. Enter the DMT vape pen. Bob Wold, founder of Clusterbusters, describes it simply: one inhalation, pain gone in 30 seconds. Joe McKay, a retired NYC firefighter and longtime sufferer, keeps one at his bedside. Takes a hit during a nighttime attack and is back asleep within minutes. He returned all his oxygen equipment after years of relying on it. The pharmacology is almost tailor-made for this use case. Onset in seconds with a duration of 10 to 15 minutes. It works at sub-perceptual doses with no tolerance buildup. A single cartridge treats 40 to 50 attacks. The whole thing fits in your pocket. The mechanism of action makes sense too. DMT is a serotonin 2A receptor agonist, structurally similar to the triptans already prescribed for cluster headaches. The difference is that conventional triptans don't abort cluster cycles or extend remission the way psychedelic tryptamines appear to. Same receptor family, but psychedelics seem to do something the pharmaceuticals can't. What would it look like if every cluster headache patient had access to a DMT vape pen that could end their worst attacks in seconds? Picture below is from the underground market.
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Overtime
Overtime@overtime·
This angle of Wemby’s game winner is wild (via hannah.colemannnn/TT)
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Austin Justice
Austin Justice@AustinJustice·
Waymo vs Humans in Austin in FY2025
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Patrick Heizer
Patrick Heizer@PatrickHeizer·
The US ethanol standard is arguably the worst current policy on the books. We waste ~35M acres on a crop that extracts and destroys our soil, pollutes our rivers and air, worsens our food supply, all while subsidizing oligarchies like John Deere, Monsanto, Syngenta, Cargill, and the oil industry, and it doesn't even lower carbon emissions. Imagine if instead we used those acres for widespread regenerative agriculture, animals actually living on the land, under and around perennial crops that produce actual nutrition, cleaning our waterways while promoting biodiversity, while simultaneously increasing wild and protected lands and public recreation areas. A society built around life, not corn.
Jason,@jasonc_nc

Effectively all growth in corn production over the last 20 years is for ethanol. ~20 million acres of conservation land, grassland, and soybean rotation was turned into corn monoculture that effectively strip mines the topsoil. Meanwhile it’s the most fertilizer dependent crop with only a 40% uptake rate. So ~1.7 million tons of nitrogen runoff flows into the Mississippi basin annually while also polluting their own water supplies. This runoff ends up expanding the Gulf deadzone, which is also where 40% of domestic seafood comes from. It’s hard to find a worse way to create fuel, with a wicked level of waste and downstream consequences.

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Amir
Amir@AmirAminiMD·
The GDP is meaningless as an indicator when the entire system is a giant Ponzi scheme built on misinformation, corruption and perpetual war. The US is in decline because nobody buys the story of the American dream anymore. But in short: 9 out of the 10 top universities in the world are now located in China, according to recent rankings. The only reason the US has managed to somehow stay competitive in recent years was the H1B visa / foreign PhD students and scientists. Well that’s gone for good -along with a rapid overall decline in international applicants. Couple that with the shittiest and most expensive healthcare system in the world, the worst and somehow also most expensive education system in the world, non-existent labor rights, institutional racism, the highest incarceration rate and percentage in the world, never-ending mass shootings, and half the population brainwashed into believing all of that is normal - and you will quickly realize that it’s by design. That the root cause lies in a fundamentally flawed political system, an oligarchy represented by a monopoly masquerading as a duopoly controlled by special and foreign interests via SuperPacs, SuperDelegates, billionaires, gerrymandering, supporting mainstream media companies, good old racism, bribery and extortion - effectively turning the US into a political circus with a giant army. A circus full of clowns that can be purchased by anyone in the world with access and enough money. A circus that has turned almost the entire world against itself, something unimaginable only a decade ago. A circus with a giant army that is rapidly running out of countries to bomb and steal resources from.
behzad@behzadnouri

@AmirAminiMD Give one objective measure that shows that US is on the decline. GDP? number of mega-cap companies? number of startup companies? top universities? net immigration of skilled workers? military power? geopolitical impact? …

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Essential Mastery
Essential Mastery@EssentialMastry·
“Five minutes after birth, they decide your name, religion, nationality and sect. And you spend the rest of your life defending what you did not choose.” - Arthur Schopenhauer
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Simon Maechling
Simon Maechling@simonmaechling·
I’m a chemist. I need to say this - because it’s getting dangerous out there. The biggest health myth in the world isn’t about vaccines. Or GMOs. Or fluoride. It’s the root of all of them. It’s called chemophobia - and it’s killing science. Fear of “chemicals” now drives vaccine rejection, GMO bans, food hysteria, and entire political movements. From tampons to tap water, people have been taught to fear chemistry - the very thing that keeps us alive. Chemophobia tells us: “Natural is good.” “Synthetic is bad.” That’s a lie. Botulinum toxin is 100% natural and one of the deadliest molecules known. Aspirin is synthetic and life-saving. We’ve gone from banning harmful substances for good reason…to banning safe, well-tested molecules for emotional reasons. You’ve seen the slogans: “If you can’t pronounce it, don’t eat it.” “Paraben-free.” “Clean beauty.” They sound empowering. But they’re not science - they’re marketing. And they’re making the world dumber, poorer, and sicker. Your body doesn’t care if a molecule comes from a plant or a lab. Vitamin C is vitamin C. Formaldehyde is formaldehyde and your body makes more of it every day than any vaccine ever could. Dose matters. Source doesn’t. This fear isn’t harmless. It shapes public policy. It blocks innovation. It raises food prices. It slows down cancer treatments. Chemophobia is now mainstream and it’s costing lives. Scientists aren’t losing because we’re wrong. We’re losing because fear spreads faster than facts. Because influencers sell fear for clicks. Because lawyers monetize doubt. And because scientists are too tired to fight back. So here’s my message, as a chemist and as a citizen: Learn how toxicology works. Call out chemical fear-mongering. Support policies based on evidence, not emotion. Chemistry isn’t the enemy. It’s the reason you have clean water, safe food, and modern medicine. If we let fear win, we lose all of it.
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Decoding Fox News
Decoding Fox News@DecodingFoxNews·
A Trump quote without his voice or face - Trump without Trump. This is for folks who might normally tune out or refuse to listen to Trump. Everyone should hear this quote. This is from his meeting on 3/3/26 with the German Chancellor Friedrich Merz
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Conspiratorial Templates
Conspiratorial Templates@mynamehear·
Why don't we have universal healthcare? Republicans. Why don't we have high speed rail? Republicans. Why are the human rights of black people, brown people, and women backsliding? Republicans. Why do a couple hundred people have 90% of all wealth in the country? Republicans. 1/
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Reads with Ravi
Reads with Ravi@readswithravi·
This paragraph from Carl Jung hits so hard. “The world is full of people suffering from the effects of their own unlived life. They become bitter, critical, or rigid, not because the world is cruel to them, but because they have betrayed their own inner possibilities. The artist who never makes art becomes cynical about those who do. The lover who never risks loving mocks romance. The thinker who never commits to a philosophy sneers at belief itself. And yet, all of them suffer, because deep down they know: the life they mock is the life they were meant to live.”
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Massimo
Massimo@Rainmaker1973·
«When you are dead, you don't know you are dead. It's pain only for others. It's the same thing when you are stupid» — Richard Feynman
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Essential Mastery
Essential Mastery@EssentialMastry·
“The more you understand this world, the more you destroy yourself. That's why fools are happy, and intelligent people live in loneliness.” - Fyodor Dostoevsky
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Poetic Outlaws
Poetic Outlaws@OutlawsPoetic·
"I’ve always been a loner. I’ll be straight; I just don’t like most people—they tire me, mix me, jiggle my eyeballs, rob me, lie to me, fuck me, fool me, teach me, insult me, love me; but mostly they talk talk TALK until I feel like a cat reamed in the ass by an elephant." --Charles Bukowski
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Nury Vittachi
Nury Vittachi@NuryVittachi·
THE PLANNED U.S. ATTACK ON IRAN has a hitch: most of the missile-targeting crew are queuing for toilets on the lead vessel, the USS Gerald R Ford. This is not a joke. A set of emails was obtained by NPR, a US public broadcasting group, revealing that toilet wars have broken out on board the most expensive ship the US Navy ever built. The Wall St Journal followed up to confirm the tale today. TLDR Summary: There are too few functioning toilets for 4,600 sailors and the problem is worsening daily—there’s no chance of fixing the system without returning the ship to the US dockyards. . BIG PROBLEMS TO DISCHARGE Problem one: Design planners screwed up by including too few toilets for 4,600 sailors, leading to 45-minute queues on a daily basis. Problem two: Engineers screwed up by installing a fragile vacuum system in which a single valve breakdown on one toilet can stop all the toilets in an entire department functioning—making the queues even longer. Problem three: Some of the temporary repair operations (such as using an acid flush to clear out calcium build-ups) can only be done while the ship is docked: no prospect of that. But with so many toilets out of order, too much pressure is put on the ones still working, so the problem will just spread. . KEY PLAYER IN U.S. ATTACKS And the issues have been gradually mounting for more than a year. “A March 18, 2025 email from the engineering department sent out to all chiefs on the ship said there were 205 [toilet] breakdowns in four days,” the NPR reported. The ship is at the heart of US overseas attack operations, working for months in waters near Venezuela, to support the abduction of the country’s president and the seizing of ships carrying oil to customers, and is now heading the planned regime change operation in Iran. Israel wants a pro-Netanyahu leader installed, as the US has done in many other countries. But how can they attack Iran while staff are queuing for the loo? . WAR OF WORDS ON BOARD One result of all this is war between sailors and on-board sewage staff (called Hull Technicians, or HTs). One sewage engineering head complained that the sailors put all sorts of problematic material down the toilets, including t-shirts: “Our sewage system is being mistreated and destroyed by Sailors on a daily basis. My HT's are currently working 19 hours a day right now trying to keep up with the demand.” Sigh. And the US taxpayer spent US$13 billion on the ship. On the plus side, it would be delightful if the carrier’s desperate lack of functioning toilets caused the attack on Iran was cancelled or postponed.
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Wall Street Apes
Wall Street Apes@WallStreetApes·
Consumer Reports just went through the data and found the cheapest and most expensive places to get groceries. They used Walmart as a baseline The most expensive places are: (In order) Trader Joe's Albertsons Tom Thumb Big Y Vons Mariano's Jewel-Osco El Rancho Shaw's Whole Foods The cheapest place are: (In order) Costco Wholesale BJ's Wholesale Club Lidl Aldi WinCo H-E-B Walmart Breakdown of percentages shown in video
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Gregory Geisler
Gregory Geisler@gregorya57·
@DeeWaynee94 We couldn't pull this off with 21st century technology! Every scientific discipline has thoroughly debunked the idea that this was ever possible.
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