Abigail Groff

We're hiring for a bunch of technical roles at @Conception This is arguably the most complex research problem in biotech, and the potential for impact is massive Apply on our website if you're up for the challenge and think you're a fit!

IVF without injections, the ability for women to safely have children later in life and for cancer survivors to have children. Highly recommend reading @Conception's update if you want a glimpse into what the future of fertility looks like

Women are born with every egg they’ll ever have. The count falls from about a million to roughly 25,000 by 37, and the eggs that remain keep aging. No one can make a new one. That’s the timer on fertility, and why IVF gets harder with age. @Conception says it just built a way around it. From a blood draw, they grew human eggs inside a tiny ovary also made from stem cells. The eggs have begun meiosis, the special division that halves a cell's 46 chromosomes to 23. That halving is what makes an egg an egg. A world first, they say. It matters because the starting cell is skin or blood, so ovarian age stops setting the limit. The road here ran through mice. In 2016 Katsuhiko Hayashi's lab turned a mouse skin cell into an egg, then live pups. Humans stalled for years. Mitinori Saitou's team reached the egg's ancestor, but no one could build the follicle an egg ripens in or start meiosis in a dish. Conception says it cleared both. These eggs only began meiosis. They haven't completed it, nothing's been fertilized, nothing published, no safety data. If it holds, it reaches cancer survivors, women in early menopause, women who started late, two-dad families. Half the world, at every age. This could be truly revolutionary.

Read more at the link -- we're hiring a ton too. So so proud of the team at @Conception!! conception.bio/science-and-up…

Very proud of this team and the work we're doing at Conception!

@kaia_mattioli @PierceOgdenJ @CUDenver Congrats Kaia!! Well deserved and so excited for you!!

super excited to share that I'm starting as an Assistant Professor at @CUDenver this fall! my lab will be right in downtown Denver :) mattioli-lab.org i'm hiring! if you're interested in joining us to study how alternative isoforms contribute to cancer, please reach out

Open source easy-start cloud compute infrastructure for bio. Looking for testers— if you’re a small start up or lab that could use compute infrastructure support, please reach out! bioaf.co

@kaia_mattioli Woah!! Wild and I’m glad you’re alright!! What a journey!

Earlier this year, I learned I have a pathogenic variant in BRCA2, which gives me a very high lifetime risk of breast cancer (55-69%), as well as an increased risk of ovarian cancer (12-29%) and pancreatic cancer (5-10%). 🧵1/ …

I’m thrilled to share that our paper “Machine-guided design of cell-type-targeting cis-regulatory elements” was published online in @Nature. nature.com/articles/s4158… #genomics #MachineLearning #SyntheticBiology #bioengineering 1/9

Women lose >90% of their #eggs by their mid-30s, with persistent #DNADamage driving this loss. But why isn’t this damage repaired? Our new work in @CurrentBiology, led by @ninadini_sharma, reveals the causes of high DNA damage in aged oocytes.🧬💥 bit.ly/48e35Ee (1/13)

Check out our blog post on developing deep learning models to predict fetal well-being during labor, using an open source dataset of time series signals consisting of fetal heart rate and uterine contractions and patient clinical data.

Fantastic work from the @AppelGroup including Schmidt Science Fellow @AndreadAquino7 Incredible innovation on such a critical issue

@marta_mele_m @mele_lab @BSC_CNS @Bioinfo4women Congrats Marta!!!

Thrilled to be officially tenured!! 🙌🙌🙌 A huge thanks to the amazing present and past members of the @mele_lab as well as my collaborators who made this possible! @BSC_CNS @Bioinfo4women

Want to hear about the latest updates/new techniques in single cell and spatial genomics? Check out my lab's eighth annual Single Cell Genomics Day on March 29. Keynotes from @IdoAmitLab @JD_Buenrostro and Xiaowei Zhuang. Please RT/spread the word! satijalab.org/scgd

New 2-year postdoc position available in my lab @TheCrick to test novel therapies for #IBD and related diseases by targeting a master regulator of #macrophage-driven inflammation using antibody-drug conjugates and related tools. Apply here: crick.wd3.myworkdayjobs.com/External/job/L… Pls retweet!

@ezgi_hsuleyman @UFScripps @darnelr Congrats Ezgi!!! 💃🏼💃🏼

Incredibly excited to announce that I’ll be joining @UFScripps as an Assistant Professor in 2024! My lab will study synaptic RNA & mitochondrial regulation to unravel how the brain adapts to experiences and encodes memories. Thankful to @darnelr for endless support. (1/3)

On Tuesday November 8th - Vote! ⁦@docs4fertility⁩ #RoeRoeRoeYourVote #reproductiverights

We're building a growing list of all the amazing labs working on female reproductive health. BUT we know there are some hidden gems. Can you help us find them? 💎👩‍🔬 bit.ly/3RJ1o8g

The wordcloud of names of the authors of the published articles in top-5 journals between 2005 and 2020.