Gus McFarlane

Editorial: "AI and SynBio Meet CRISPR Heralding a New Genome Editing Era" @CRISPRchef liebertpub.com/doi/10.1089/cr…

We’re getting excited for @CSHL’s CRISPR Frontiers meeting! We'll have 4 posters on a variety of topics—see the video below to learn more. Looking forward to seeing you there: idtb.io/r4qiks #CRISPR #CSHL24 #CSHL

Scientists are editing out the caffeine genes using CRISPR genome engineering to develop a "natural" decaf coffee, to avoid the messy chemical process to remove the caffeine in use now. Will you drink it? slate.com/technology/202…

NHS to offer first CRISPR gene-editing therapy for beta thalassaemia. This breakthrough could eliminate the need for lifelong blood transfusions, with promising trial results. Cost: £1.6m per patient. bbc.com/news/articles/…

Alison Van Eenennaam (@biobeef), an animal geneticist @ucdavis, uses CRISPR technology to eliminate horns on dairy cows, create all male offspring in cattle, and generate sheep that model high blood pressure. Read more about her endeavors here: bit.ly/4cM1pTU

Check out our new research note in @BioMedCentral on using CRISPResso2 with Nanopore sequencing data! Efficient, cost-effective gRNA screening! #CRISPR #Nanopore #DNA #GeneEditing rdcu.be/dPvYU

Winners of the NAS Prize in Food and Agriculture Sciences lead pioneering research in genetics, atmospheric science & CRISPR systems to bolster pollinators, safeguard crops & livestock, & enhance #foodsecurity. Nominate for the 2024 award today! ow.ly/qlvC50PJtHE #NASaward

New Research: Tackling mosaicism in gene edited livestock frontiersin.org/articles/10.33… #FrontiersIn #AnimalScience

Just shared at @KeystoneSymp a new @ArcInstitute discovery of the bridge RNA recombinase mechanism: a new class of natural RNA-guided systems that retains the key property of programmability from RNAi and CRISPR while enabling large-scale genome design beyond RNA and DNA cuts

What if we could universally recombine, insert, delete, or invert any two pieces of DNA? In back-to-back @Nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design

CRISPR tweaks to sugarcane leaf angles boost biomass by 18%. This breakthrough could revolutionize biofuel production and crop yields globally. @ZMEScience buff.ly/3Xt3QGl

A CRISPR gene editing therapy has delivered effective, long-lasting treatment for cystic fibrosis in mice after overcoming a major hurdle that stymied previous genetic therapies. #Echobox=1719028795" target="_blank" rel="nofollow noopener">newscientist.com/article/243556…

Today we report in @natBME the eePASSIGE system, which uses evolved and engineered recombinases and prime editing to integrate large gene-sized DNA cargoes into the mammalian genome in an efficient, precise, and targeted manner. (1/13) drive.google.com/file/d/1WDMVqL…

Exciting news! 🐄🐑🐖 Check out our latest publication: "Tackling Mosaicism in #GeneEdited #Livestock". We describe how #CRISPR advancements are paving the way for more efficient, sustainable breeding programs #LivestockInnovation #SustainableFarming frontiersin.org/articles/10.33…

What if there was an antibiotic that doesn't disrupt the gut microbiome? There is now. A discovery published @Nature today nature.com/articles/s4158… @PaulHergie and colleagues @UofIllinois @justsaysinmice

Radar Therapeutics raises $13 million to design therapies using RNA sensors #NBTintheNews via @GENbio genengnews.com/topics/drug-di…

Research alert! 🐝 Check out our paper on #CRISPR #Cas9-targeted #nanopore sequencing of #Varroa destructor during Australia's recent outbreak. Rapid & accurate identification is crucial for response. @nswdpi frontiersin.org/articles/10.33…

Dive into the future of #biocontrol! Our paper on #CRISPR "#Gene #Drive: Past, Present & Future Roads to Vertebrate Biocontrol". Learn how this tech could revolutionise pest population management in a species-specific way. mdpi.com/2132882 @roslininstitute @nswdpi

CRISPR therapy restores some vision to people with blindness go.nature.com/3JYRE86

Every CRISPRDx platform has gRNA design parameters suited to the Cas protein used (Fn/enFnCas9, Cas13, Cas12, Cas14 etc.). CriSNPr designs gRNAs across different platforms (SHERLOCK, DETECTR, FELUDA, RAY etc.) and returns optimal guides for assay validation (2/n)