Adrian Janiszewski

Happy to share our recent publication about conventional IVF, where we reviewed strengths and weaknesses of one of the most practiced assisted reproductive technology (ART) approaches used worldwide. lnkd.in/dR7GaA3C #ivf #science #reproduction #fertilitytreatment

Confused by all the "what is epigenetics" discourse? Well I have just the thing for you -- presenting the Epigenetics Alignment Chart!

🎉 Happy to share our study, now out in @NatureCellBio! This is the result of an amazing collaboration of our lab @vincentpasque (@KU_Leuven) with @RuggGunnLab (@BabrahamInst), @hendrik_marks (@Radboud_Uni) & @MaartenDhaenens (@ugent). A 🧵… [1/19] nature.com/articles/s4155…

On May 8th, I was at work and it happened to be Mother’s Day. I started the day thinking: “Today we have the chance of making new Moms”. I don’t know if it was the positive energy but all our patients of that day became pregnant🤰🏻 This work will never stop to amaze me ✨

Excited to share our latest work in @ScienceMagazine (science.org/doi/10.1126/sc…). Building on the foundational work of the PCAWG and HMF consortia, we established a compendium of mutation events in somatic whole-genome sequencing data of 3,949 patients from 19 tumor types.

Our paper describing gene regulation in the fly brain is out now in @Nature! So proud of this one and of the amazing team work with @SaraAibar @ibrahimihsan and @joynismail in the @steinaerts lab! Check it out here go.nature.com/3ETX2EF with below our main findings:

@GeorgolG @jeffvierstra @NatureComms Congrats Grigorios! A beautiful piece of work! :)

So happy and relieved to finally see our work with @jeffvierstra out in @NatureComms. Here we study how the cis and trans regulatory landscape temporally synergize to establish lineage commitment and differentiation during #hematopoiesis. nature.com/articles/s4146… Summary 🧵 below

Excited to share our latest publication out @CellCellPress where we explore how Xist nucleates local protein gradients to propagate gene silencing during X chromosome inactivation. 1/15 dlvr.it/SBxrs9 🧫🧬🔬🧵

Make sure to check it out and see how we leveraged single-cell allele-resolution RNA-seq and bulk ATAC-seq to better understand X chromosome dosage compensation!

It's been an amazing team effort with @IreneTalon, @vincentpasque and all collaborators who helped us immensely.

Excited to share that our latest study: “Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals” is out in @GenomeBiology!

Thrilled to share our paper on the mutational landscape of human somatic and germline cells @Nature. We integrated histology and genomics to explore the genetic diversity that develops within our bodies as we age. nature.com/articles/s4158… An illustrated tweetorial… [1/15]

I have just published Deep Learning on Human Microbiome at Medium / Towards Data Science nikolay-oskolkov.medium.com/deep-learning-…

Delighted to share the latest @PayerLab preprint about the implications of #Xchromosome activity on meiotic entry in #mouse primordial germ cells #PGCs in vitro biorxiv.org/content/10.110… 1/

Excited to share our work published in @ScienceMagazine led by our DPhil @LisaRodermund, jointly supervised by @LSchermelleh and us. (1/3) science.sciencemag.org/content/372/65…

Very excited to share with you our pre-print linking Wnt deregulation with carboplatin resistance in Breast Cancer! @willyaaoliveira @DevReg_KULeuven @scil_leuven #Wntpathway biorxiv.org/content/10.110…

Thanks to everyone who contributed; @vincentpasque, @GeorgolG, @lab_lluis, @BalliMartina, @PAthanasouli, @embojournal and a very helpful editor.

Check out our EMBO News&Views “Keep the fate: how chromatin regulators safeguard embryonic stem cell identity“ here: embopress.org/doi/epdf/10.15…  and the discussed article published in the EMBO journal: embopress.org/doi/full/10.15…

In our recent News & Views article in The EMBO Journal @embojournal we introduced and discussed very interesting new findings from the Joerg Betschinger group @FMIscience who identified chromatin regulators that restrict the developmental potential of mouse embryonic stem cells.

How can genes decode information with a defined logic? In our new @biorxivpreprint led by @RutgerGjaltema and @TSchwammle we dissect the regulatory landscape of Xist and find a distal-proximal hierarchy that generates a logical AND-gate. biorxiv.org/cgi/content/sh… A thread