Jeremy Gungabeesoon

Excited to share my PhD work in the @PittetLab, published today in @CellCellPress! We show that immunotherapy can expand a distinct interferon-responsive neutrophil state that contributes to successful responses to therapy: sciencedirect.com/science/articl…

📢 Research Alert! 🧬🔬 🩺 We are super excited that our latest study, led by the great @RubenBill5 & Asa Wirapati, is out: science.org/doi/full/10.11… We set out to shed some light on the tumor microenvironment and its impact on cancer progression. 🧵

SPOTLIGHT: @BBS_Harvard @PittetLab @jgungabeesoon demonstrated that neutrophils exhibit remarkable plasticity and could acquire an antitumor phenotype in response to immunotherapy. bit.ly/3KU2Nsb

The findings suggest that researchers may be able to manipulate neutrophils to make cancer therapies more effective hms.harvard.edu/news/how-lowly…

Read more about my PhD work here! @PittetLab @KleinLabHMS

The Garris Lab @MGHCSB @MGH_RI @harvardmed is looking for curious and driven postdoctoral fellows who want to investigate the biology of #dendriticcells in cancer growth and therapy. Interested candidates should send their CV and cover letter to positions@garrislab.com

@ArianaYoum @RyanGosling Congrats ari 👏👏👏

Glad to feature @RyanGosling in my first, first-author paper. Thank you to my mentor & collaborator Morris Moscovitch 😊 authors.elsevier.com/a/1dgK06TBFsXKX

1/ 🤩Whoah! I'm so excited to be a part of this awesome @MempelThorsten study, led by @DiPilato and colleagues. It shows a mechanism by which "good" cells (i.e. antitumor CD8 T cells) can survive in tumors to do their job. cell.com/cell/fulltext/…

The intrepid Mauro (now @DiPilatoLab) and team did it again: CXCR6 enables CTL to control tumors by guiding their interactions with CCR7+ cDC in perivascular survival niches of the tumor stroma. Thanks to our fantastic collaborators. See 🧵 for details. cell.com/cell/fulltext/…

Immune networks within the glial cell ecosystem maintain brain health. Our latest is out today in @nature. Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease. This was a wonderful collaboration with @RudyTanzi and his team. 1/ nature.com/articles/s4158…

Are brain borders the new bone marrow? New work from the @mzhlab complements recent findings from the @TheColonnaLab and @jonykipnis labs to show brain-dedicated B-lymphopoiesis! A pleasure to contribute our little grain nature.com/articles/s4159…

It’s out! My PhD work focusing on toxicities associated with anti-cancer immunotherapy drugs: immunology.sciencemag.org/content/6/61/e… And my first #tweetorial brought to you by @PittetLab where you can learn all about our findings! twitter.com/PittetLab/stat…

A new @MGH_RI, @harvardmed study pinpoints a potential target to offset adverse effects from #cancer #immunotherapy, revealing in mice that obstructing inflammatory neutrophils in the liver prevented the toxicity of anti-CD40 agonist therapy: fcld.ly/j1e5xr4

👉Macrophages & neutrophils may drive toxicities after #immunotherapy, but NOT dendritic cells. Instead, dendritic cells, incl. DC3 (also called, LAMP3 DC, mregDC) may be key for antitumor immunity. This could be important for next gen treatments. doi.org/10.1126/sciimm…

0/ Published today in Science Immunology! Work from our lab investigating immunotherapy-driven toxicities (immune related adverse events, a.k.a. irAEs), which are a major clinical problem in cancer immunotherapy clinics. #tweetorial immunology.sciencemag.org/content/6/61/e…

Pleased to announce my latest study @RockefellerUniv published in @ScienceTM. stm.sciencemag.org/content/13/594… In this study we provide proof of concept for bladder infused CD40 agonistic antibodies as a local treatment for bladder cancer.

Low-carb, high-fat diets—including the popular “ketogenic” diet—may not be any more effective at keeping obesity at bay than those that balance calorie intake with energy expenditure, a new #SciencePerspective suggests. fcld.ly/oeb435c #WeekendReads

@ArianaYoum @NSERC_CRSNG Wooo!!!! 🎉 🙌

Super excited & grateful to share that @NSERC_CRSNG is supporting my doctoral research on how acetylcholine modulates episodic memory (through individual differences in older adults) 🤩🥳

👉The @PittetLab is hiring a #bioinformatician to pursue our work on the tumor immune microenvironment. All this in an amazing place isrec.ch/en/agora 🇨🇭... and with a great bioinformatics network @KleinLabHMS @carmonation ! Please share or let us know if interested!

@ArianaYoum Go ari 🙌

Excited for #SfNConnectome21 where I’m presenting my first grad poster!! 🧠🤩 If you have any questions, you can drop a message ⬇️, post on the Discussion board, or drop by to vid chat tomorrow Jan 12 @ 11:30 AM - 12:00 PM EST!