JM Lopez-Urdiales

No Claude, the project will not take me 2-3 months. We will finish it today.

@SantiagoPliego @pmarca Indeed.

Insane alpha in this book btw h/t: @pmarca

Analogies of numbers of neurons and numbers of transistors or gates in a silicon computer underestimate the complexity of living systems. The in-cell microtubule structure needs to be accounted for.

@BasedBiohacker Her

kid takes 5 grams of modafinil in an attempt suicide... does not die. bet this kid felt like Genghis Khan and could see the 4th dimension for a brief window of time there. i wonder what happened to him after. must be the backstory of one of the greats.

We don't have a compute problem… We have an architecture problem. Paramecium Caudatum are single-celled organisms roughly the width of a human hair. They have no brain, no neurons, no synapses, and no central nervous system of any kind. But what they do have is ~100,000 microtubules… With that substrate alone, they can: → Swim in controlled helical trajectories → Modulate speed continuously → Execute graded avoidance reactions (reverse, pivot, resume) → Escape predators with emergency burst reversals → Fire localized volleys of 8,000 trichocyst harpoons → Navigate toward food via chemotaxis → Orient in electric fields (galvanotaxis) → Orient to gravity (gravitaxis) → Sense and navigate thermal gradients → Sense and navigate toward light → Detect and follow surfaces (thigmotaxis) → Forage biofilms → Generate feeding currents and sort particles at the cytostome → Engage in reciprocal sex with mating-type recognition, nuclear exchange, and complete genomic reconstruction → Self-fertilize when no partner is available (autogamy) → Habituate to repeated stimuli (primitive learning) → Inherit cortical MT architecture epigenetically independent of the genome 17 distinct behaviors. One lattice. Zero neurons. The coordination layer is the infraciliary lattice — a microtubule-based grid connecting all 5,000 ciliary basal bodies into a single cell-wide network. Every cilium is a terminal node on a microtubule mesh that coordinates metachronal waves across the entire cell surface — thousands of appendages phase-locked into coherent motion by a substrate that predates the nervous system by a billion years. The neuron didn't invent computation. It inherited microtubules.

Si estás planeando la observación del eclipse de Sol del 12 de agosto y quieres saber si el relieve te va a permitir verlo, usa nuestro visualizador. Tiene una nueva capa ("Visibilidad") que muestra las sombras predichas con un modelo digital del terreno: visualizadores.ign.es/eclipses/2026

Just discovered Dekal via @TimotheePeter's video modeling a spherical five-bar linkage in code. What makes it interesting: > Code-based kinematic design with a differentiable simulation engine > Describe mechanisms in code, instantly get workspace mapping, reachability analysis, and static load testing across every joint > Idea to kinematic validation ASAP; then push to CAD Its a cool project built by a mechanical engineer frustrated with iteration speed in existing tools.

The performance of almost every physical part is a combination of a Shape factor and a Material factor. Maximizing both makes for the best part. True across mechanical structures, heat transfer, electrical design, even industrial design.

@ruben_kostard @VishakhRanotra How does Forgecad with codex 5.3 compare to Opus 4.6 with Freecad? @grok

@VishakhRanotra Here is my attempt with ForgeCAD. I gave the picture to Codex-5.3 with the ForgeCAD docs. I think did pretty good for first shot. Have more examples in my profile.

Can any AI give me accurate CAD models of all these components with assembly files with a prompt?

@Object_Zero_ Maybe the real space company is not @spaceX but @xai (understand the universe in order to travel it).

You cannot build a Type II Civilisation without interstellar travel.

Fantastic article by the brilliant @ProfBuehlerMIT walking through his research evolution from MD to AI agents, ultimately building an AI Scientist. Worth the read!!

@elevenlabs 11B

We raised $500M at an $11B valuation to transform how people interact with technology.

Would it make sense to make a civilian version now? And how are the current ELINT birds? What’s your guess? @grok

@beffjezos Fewer humans

A company is a directed application of intelligence and technology to achieve a goal. AI allows us to readily transduce capital to intelligence. Companies will have less humans, but each of them will have a larger piece of the pie, and there will be far more companies overall.

@hugomercierooo Twin

𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝗶𝗻𝗴 𝗧𝘄𝗶𝗻 — 𝘁𝗵𝗲 𝗔𝗜 𝗰𝗼𝗺𝗽𝗮𝗻𝘆 𝗯𝘂𝗶𝗹𝗱𝗲𝗿. No setup. Secure. Infinitely scalable. We just raised a $𝟭𝟬𝗠 𝘀𝗲𝗲𝗱. After a beta with 𝟭𝟬𝟬,𝟬𝟬𝟬+ 𝗮𝗴𝗲𝗻𝘁𝘀 𝗱𝗲𝗽𝗹𝗼𝘆𝗲𝗱, we’re now opening to everyone. RT and comment “Twin” — first agents on us. 👇

Mars: Heart of Gold This is a fan-made AI film born out of pure optimism for the future. Not for commercial use, nor endorsed by any party. I hope I portrayed the scientific subjects in a faithful way. By Aiden Guo, from PsyopAnime Code: White.

@xdNiBoR @jusbar23 Fewer

@jusbar23 Having less satellites is indeed a critical thing when you are not SpaceX or Blue Origin.

$ASTS: Reminder: As you move farther away from earth, you have a wider field of view. This allows you to cover the earth with less satellites. Starlink needs hundreds of satellites to provide the same amount of coverage as a single AST Spacemobile satellite. These constant disconnects and reconnects drains your phone faster than if you were connected to a single satellite. The massive antenna size of an AST satellites lets them operate farther due to having more power to mitigate the loss in signal (Inverse square law)

WTF is a Gyrotron? A gyrotron is a class of high power vacuum tubes that generates microwave radiation beams. A gyrotron can produce a beam that is 20 GHz to 1THz, this includes a few frequency bands where the Earth’s atmosphere is transparent to radiation. That means you can build a gyrotron that beams energy through the atmosphere. What makes gyrotrons different to a lot of other beam sources is that you can already build a 1-2 MW gyrotron today. This means you can build very high power directed energy weapons with beam outputs that have frequency that allows the beam to travel through the Earth’s atmosphere. This is an obvious dual use technology, it’s the basis for a directed energy weapons, and it’s also the basis for a Nikola Tesla type wireless energy transmission system. How does it work? - see diagram on right. In a magnetron (the typical type microwave that we are all used to) when operating frequencies increase, the resonant cavity structures must decrease in size, which limits their power-handling capability. Gyrotrons are unlike conventional microwave vacuum tubes such as klystrons and magnetrons, in which the wavelength is determined by a resonant cavity. In the gyrotron, a hot filament in an electron gun [1] at one end of the tube emits an annular-shaped (hollow tubular) beam of electrons [6]. This beam is accelerated by a high-voltage DC anode and then travels through a large tubular resonant cavity structure [2] in a strong axial magnetic field, usually created by a superconducting magnet around the tube [8]. The field causes the electrons to move helically in tight circles around the magnetic field lines as they travel lengthwise through the tube. At the position in the tube where the magnetic field reaches its maximum the electrons radiate electromagnetic waves, parallel to the axis of the tube, at their cyclotron resonance frequency. The millimeter radiation forms standing waves in the tube, which acts as an open-ended resonant cavity, and is formed into a beam. … So by forcing the electrons to fly in this helical path and then squeezing the helical paths with a giant magnet you rip radiation energy from the electrons in the form of a powerful microwave beam. Crucially… Unlike a resonant cavity magnetron the gyrotron architecture is extremely scalable. You could build a 10 MW gyrotron or a 100 MW gyrotron. This is one of those tech rabbit holes that you can fall down, and you can sketch a lot of very cool ideas. But nobody ever builds anything. Quaise Energy build gyrotrons for drilling oil wells without drilling bits, but not many other people out there are making use of this tech. There should be a gyro-transmission company and a gyro-defence company, and a bunch of other things. Where are they?

@damianplayer Ralph