Jon Watts

The RTI & @UMassChan Medical School seeks the next generation of scientific leaders! Join our research community as a Maraganore Early Independence Fellow. Get 3-5 years of support. Apply by Dec 1 to join us: academicjobsonline.org/ajo/jobs/28425

Hey, senior PhD students working on RNA and moving toward leading independent labs: Apply for the Maraganore Early Independence Fellow program at @UMassChan @RTI_UMassChan and come work with us! linkedin.com/posts/angelame…

Ribosomes unexpectedly moonlight as activators of angiogenin enzyme nature.com/articles/d4158…

So proud of the RTI’s fearless leader Phil Zamore @zamore_lab for receiving the @RNASociety & @CSHL Distinguished Research Mentor Award! CONGRATS 🎉 #RNA24

CONGRATULATIONS to our newest PhD, Dr. Adam Hedger, co-mentored by @jwattsgroup and Dr. Celia Schiffer!!!

Seems like they missed an opportunity here -- they could have called the combined company the Ornery Renegades... @orna_tx @ReNAgadeTx #RNA

Congratulations Phillip Zamore of @UMassChan, newly inducted #NASmember! #NAS161 #genetics #medicine

Congratulations to the newly minted Dr. @Samantha_Sarli for passing her thesis defense @RTI_UMassChan @UMassChan with a great defense talk.

Are oligonucleotides that are chemically optimized for normal brain also active in glioblastoma brain tumors? 👇 @FakihH9 @jwattsgroup

Loving Sudhir Agrawal's cover art for Nucleic Acid Therapeutics, cleverly reflecting the decades of work that have brought our field to its current state!

In the latest paper from senior PhD student @Samantha_Sarli, we compare the activity profile of conjugated and unconjugated ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo. Amphiphilic lipids help drive safe uptake! Online now at NAR: academic.oup.com/nar/article/do…

Congrats to @SchaferLabUMass on this well deserved award!

#newscience alert in @naturecomms ! How can you make Nme2Cas9 editing Harder-Better-Faster-Stronger? Check it out! pubmed.ncbi.nlm.nih.gov/38368418/

@bsw5020 I love this so much.

This is the moment that we first found out about the amazing grant from Mackenzie Scott and her incredible foundation. I am so proud of the amazing IAA staff and community. As you will see, disbelief turns into happy tears. Today, I cannot stop smiling.

Watts lab research was selected to compete in STAT Madness again this year! This time the featured research is our collaboration with Joel Richter's lab, building on their key insight that splice-switching ASOs may be therapeutic for Fragile X. Vote here: statnews.com/feature/stat-m…

Erik Sontheimer, PhD; Jonathan Watts, PhD; and Scot Wolfe, PhD, have received $2.3 million from the Rett Syndrome Research Trust to target particular mutations in the Rett syndrome patient population: brnw.ch/21wHyVM #AdvancingTogether @ESontheimerLab @jwattsgroup @RSRT

Read more about it: UMass Chan studies selected for STAT Madness umassmed.edu/news/news-arch…

Just out: our new genome editing fluorescent reporter mouse is compatible with multiple Cas nucleases and PAM sequences, and reports on both nuclease and prime editing. With @ESontheimerLab and @xue_lab.

Original Research: In Vivo Prime Editing by Lipid Nanoparticle Co-Delivery of Chemically Modified pegRNA and Prime Editor mRNA @ESontheimerLab @jwattsgroup liebertpub.com/doi/10.1089/ge…

So many emotions. On one hand, I'm glad that the publishers of my fifth-grader's math textbook decided that chemistry was the best example of "modeling real life" to put on their cover. But could they not have talked to an actual chemist about the nature of bonding in NaCl first?