Kevin Ho

Had to jump in and experiment with @_chenglou's Pretext. BioMap is a 52 biomarker blocks that expand as you explore, reflowing text across every block every frame. 0.04ms for all 52 layouts only possible with Pretext turning text measurement into pure math. No DOM reads, no reflows. kevinho.com/experiments/bi…

@joulee A/S/L

My recent weekend vibe coding projects: restoring the vintage internet of my youth.

Accurate

Supercharge your agents with Super Carl.

@joshpuckett Looks great! Time for some new design tools for creating great MacOS apps!

Pushed a small update tonight, 1.0.8: - Drag typefaces from the grid/list into any Collection or Style in sidebar - Right-click bulk changes now show a confirmation dialog. - Logo images can be dropped anywhere on the window, not just the toolbar. - Scroll position is preserved per sidebar view - Press A–Z on the grid/list to jump to the first typeface starting with that letter - New System tag on grid/list shows fonts installed by macOS

Pica is a fully native app for managing your fonts on MacOS. Organize into collections, test color themes and logos, watch folders, manage what's installed, and much more. Available for free at pica.joshpuckett.me

How accurate are wearables like Apple Watch, Whoop, and Oura? A researcher compiled 16 studies to find out, and the answer might shock you:

The 5th dimension explained

You are not talking to somebody that woke up a loser!!

BREAKING: Max Levchin (@mlevchin), Co-Founder of PayPal & CEO of @Affirm — HQ Tour A Masterclass in: Espressos → Big Lebowski → PayPal lessons → Affirm → Economics of AI The Dude abides. “The net IQ of the world Is about to go up 50 points” Result: As intelligence becomes normalized, bad actors & "fine print" companies will get exposed faster. We cover: • Capitalism vs the “warm embrace” of socialism • You can’t perfectly time an IPO • The best time ever to be a CS CEO • AI collapsing the cost of intelligence • Great economic shift underway Strikes & gutters, ups & downs. Recorded at Affirm HQ, March 30, 2026 𝐓𝐈𝐌𝐄𝐒𝐓𝐀𝐌𝐏𝐒 (00:00) Max Levchin, Co-Founder & CEO at Affirm (01:35) Inside Affirm's office espresso bar (06:46) How the love for espressos started at age 5 (10:30) Truth about bad coffee beans (13:51) Strava & cycling (14:56) Meeting Alfred Lin & Tony Hsieh over poker (21:14) Onboarding 800K Shopify merchants in one week (22:59) Big Lebowski in every shareholder letter (32:11) The PayPal lesson that built Affirm (35:25) Being a technical CEO (37:57) Why this is the best time to be a technical CEO (42:10) Should engineers still learn to code? (44:48) Side quest with AI (46:59) Companies AI will destroy (49:46) How AI has changed engineering at Affirm (50:54) Agentic commerce & DoorDash (52:28) Devolution of Credit (55:06) Biggest misconceptions about BNPL (57:42) Being a public company CEO (01:07:01) Advice for private companies (01:11:09) Creating his own economy (01:14:29) Can AI help solve the $39T debt problem? (01:16:00) Learnings (01:17:46) Will average IQ rise or fall?

@PolymarketSport For basketball fans, this is like solving cancer.

🚨TRENDING: A Reddit users just found a way to end tanking in the NBA: - All arena beers start the season at $10 league-wide - For ever win, teams can sell beer for + $0.35 - For ever loss, teams must DROP beer price -$0.20 If this were in place, Wizards would have to pay fans 10 cents every time they ordered a beer.

“The most beautiful thing we can experience is the mysterious. It is the source of all true art and science.” — Albert Einstein

@TiffanyFong I feel like it’s only allowed after you infused your son’s blood into yourself.

should i announce next time i have sex

@Grimezsz Intriguing!

HIRING : Who is the best engineer who also has a sense of aesthetics? JOB DESCRIPTION: monk. I have manuscripts that need to be illuminated We need to do this in a week - please apply

@bryan_johnson Hi Bryan, I'm building Otto Lab (ottolab.com/?ref=x) as the data layer for all of your labs, dexa, v02, wearables, health stacks, etc. I would love to see if there's way to collaborate.

I've measured my body a lot. I'm about to dwarf what we've done by building real-time continuous multi-omic monitoring and intervention. Cars drive themselves. Software writes itself. I'm building Autonomous Health. First for me, then for you. > Peptides in circulation (dose and efficacy in real time) > Gut and oral microbiome profiling > Transcriptomics and gene expression > Mitochondrial genome sequencing and mutational tracking > Real-time cell cultures > Longitudinal proteomics (heat shock response panel) > Inflammatory cytokine panels > Mitochondrial function, ROS, cell viability Continuous environmental monitoring including light, noise, air, water, pollutants. If you’re into this kind of stuff, come build with me. If you're building bioinfrastructure relevant to this, get in touch.

The hidden architecture of a bird’s voice. 🙌🏻 Did you know a bird's song can be mapped into a mathematical fingerprint? 🧬 This isn't sci-fi; it's the real-time mapping this is a multi-dimensional bioacoustic visualization of a Carolina Wren's song. By tracking the frequencies, can build a unique radar chart signature for the species. It tracks spectral flatness , entropy, and slope in 3D space to reveal the hidden geometry behind the music. Nature is literally math in motion. the video tracks specific spectral features that define the bird's unique Vocal Signature. 🥺 A beautiful reminder of the complexity hiding in everyday sounds.

Cells That Talk in Molecules Biology Might Be More Programmable Than We Think A molecular communication system treats signaling molecules like message carriers. One cell releases them into the surrounding fluid, they wander and drift through space, and another cell reads the message by counting fresh binding events at its receptors. Here, a 1 is sent as a burst of molecules during a symbol window, while a 0 is sent as silence. Before the real payload, we send a short pilot pulse so the receiver can calibrate the channel and line up its sampling time. Decoding is then based on new receptor-binding arrivals, passed through a matched filter, rather than just watching slow receptor occupancy. That makes the symbols cleaner to separate, even with noise, delay, and intersymbol interference in the medium.

Experiment posted here: kevinho.com/experiments/me…

I've been exploring something: instead of showing health data as charts, render it as a living cell. Something that's scientifically grounded. Your Apple Watch tracks HRV. HRV reflects autonomic balance, which is directly downstream of mitochondrial efficiency. Your watch is measuring your mitochondria, it just doesn't tell you that. Sleep stages track cellular repair cycles. Deep sleep = growth hormone release + glucose metabolism. REM = neural protein synthesis. Your watch actually measures your nucleus at work. VO2 Max measures how efficiently your cells convert oxygen to ATP. That's mitochondrial respiration capacity. Once you realize that wearable data IS cellular data, the UI question changes from "how do we visualize heart rate?" it becomes "how do we show someone the state of their mitochondria?" This could change UI quite a bit. So I built a prototype that renders 17 biometric data points as organelles inside a cell. You can drill into any organelle to see the chart, stats, and clinical explanation. I wonder if something like this could work with real Apple Health data at scale? (The XML parser exists but hasn't been stress-tested on multi-year exports). What other biological metaphors work for data? (Nervous system for network traffic?) Is the cellular abstraction actually more intuitive than charts, or just more beautiful? What would a "cell health score" look like, derived from the aggregate state? I think there's something here beyond health. The idea that data can be rendered as living systems instead of static charts feels like an unexplored design space.

Magic

Another brilliant example of how pretext can deliver smooth, real-time content manipulation in an interface that actually makes sense!

Data visualization will not be the same