Boris Djordjevic

I've built the ultimate CLI for searches; your AI agent is searching the web with one API. Mine searches 8 in parallel and returns in 850ms. → Brave + Google + Exa + Perplexity + Tavily + Jina + Firecrawl + SerpAPI + Scrapling → 13 modes (news, academic, people, patents, places) → Auto-JSON when piped. Semantic exit codes. Anti Cloudflare mode. → 5.7MB static Rust binary. Zero deps. Built for @OpenClaw and AI agents that need real web search. cargo install --git github.com/199-biotechnol… Open source. One command: search "anything"

There's a massive gap between what's possible and what's being done for pet health & longevity. AI is democratising it: cost, bioinformatics expertise, software skills - the barriers that kept this out of reach are falling away. For the first time, a motivated individual with an LLM can compress the distance between an idea and a real treatment from years to weeks.

$3,000 and zero biology training. That's what it took to design a personalized mRNA cancer vaccine for a dying rescue dog. @paul_conyngham adopted Rosie from a shelter in 2019. She's a staffy-Shar Pei cross who got him through some of the worst years of his life. Last year, she developed mast cell cancer. Every treatment failed. Vets gave her months. He's a machine learning engineer. He used @OpenAI's ChatGPT to plan the research pipeline. Sequenced Rosie's tumor DNA at UNSW. Ran @GoogleDeepMind's AlphaFold to model the cancer-driving proteins. And @grok to create the final sequence. @PalliThordarson at the @UNSWRNA Institute then manufactured a personalized mRNA vaccine in under two months. Rosie's tennis ball-sized tumor shrank 75%. She's jumping fences and chasing rabbits again. Forget every AI benchmark debate. When I evaluate what AI can do for medicine, this is the only metric I care about: saving a life. My friends @RyanBethencourt and @longevityboris are already building tools to make this kind of treatment accessible to any pet owner. The day every family can access personalized medicine for their loved ones, two-legged or four-legged, is closer than you think. ❤️

Just open-sourced clinstagram — a full Instagram CLI built for AI agents and @openclaw . No Playwright. No browser automation. No bot detection games. One command line. Three backends. The policy router picks the safest API path so your agent doesn't have to. clinstagram --json dm send @user "hey" clinstagram --json post reel video.mp4 --caption "shipped it" clinstagram --json hashtag top longevity --limit 20 clinstagram --json user posts @competitor --limit 50 github.com/199-biotechnol…

Every WhatsApp bot project eventually hits the same wall: Baileys. A Node.js library that works until it doesn't, eats 200MB of RAM to say "hello," and crashes at 3 AM when your on-call engineer is asleep. whatsrust fixes that. One Rust binary, ~15MB, handles everything Baileys does -- text, images, audio, video, documents, stickers, locations, contacts, reactions, edits, revokes, replies. It also does things Baileys doesn't: crash-safe message queues, automatic reconnection with jitter, SQLite backups on startup and shutdown, single-instance locking so two bridges can't fight over one session, plus a health endpoint that actually responds to HTTP properly. github.com/199-biotechnol…

@AdamDraper @techno0ptimist @BoostVC Interested; partial reprogramming & pet longevity?

Founders, @BoostVC is investing heavily in New Bio and Longevity. Please reach out if interested. $500k first check investments.

@agingroy @IcahnMountSinai My question is, should I take this drug? What are the benefits risks for a 'healthy' adult (healthy being an oxymoron, can't be healthy as long as aging is around)

Every longevity trial before this tested a single drug. One target, one bet. @IcahnMountSinai just launched the first combination anti-aging trial: HIIT plus resistance training, daily spermidine, and either rapamycin or lamivudine. That last one is an HIV drug. And it might be the most interesting part of the whole protocol. About 17% of your genome is made of LINE-1 retrotransposons, ancient viral sequences buried in your DNA. In young cells, they're locked down. With aging, the silencing erodes. They reactivate, reverse-transcribe into loose DNA in your cytoplasm, and your immune system treats it like a live infection. Chronic inflammation, no pathogen. That's inflammaging at its source. Lamivudine blocks the reverse transcriptase step. In aged mice, it dialed down this false alarm across tissues (De Cecco et al., Nature, 2019). The other components aren't random either. -> Rapamycin inhibits mTOR (9 to 28% lifespan extension in mice). -> Spermidine triggers autophagy (higher intake associated with being 5.7 biological years younger in a 20-year cohort). -> A 2024 paper confirmed spermidine is actually required for rapamycin-induced autophagy to work. These pathways converge. They're tracking it with 5,300 blood proteins simultaneously. The deepest inflammaging panel ever used in a human aging trial. Phase 1b. 22 participants, ages 65 to 80. @MiriamMerad and @DrTomMarron at @TischCancer. Part of the $101M @xprize Healthspan competition. We stopped treating cancer with single agents decades ago. Aging deserves the same approach.

Github if you want to test it locally. I'm really surprised by the accuracy, having much better results compared to Qwen3.5 ASR and NVIDIA Parakeet. 😄 github.com/199-biotechnol…

This is the fastest AI model for FREE audio transcription. 93 minutes of audio transcribed in 59 seconds. On a simple MacBook M4. Fully local. No cloud. No API key. I ported @nvidia 's Nemotron ASR to @Apple Silicon using MLX. 94x realtime. 618M params. Open source. pip install nemotron-asr-mlx huggingface.co/dboris/nemotro…

Local real-time speech-to-text on Apple Silicon. No API keys, no cloud, no cost. Any app can subscribe to the SSE stream. 2% WER. Runs on-device via MLX. pip install textstream-asr github.com/199-biotechnol…

The easiest way to generate Nano Banana 2 images from the terminal. For humans, LLMs/OpenClaw. $0.04 each, 3 seconds, one command. nanaban "cyberpunk tokyo street neon rain" npm install -g nanaban github.com/199-biotechnol…

@matt_elevenlabs 11B

We just raised $500M at an 11B valuation 🎉 To celebrate, we’re giving away 1,000 free credits so you can test our platform. For the next 6 hours, comment “11B” below and we’ll DM you the credits (must follow) 👇

Just open-sourced a Claude skill for SEO/GEO/AEO optimization — helps your content get found by both search engines AND AI platforms like ChatGPT, Perplexity, Claude & Gemini. Analyzes pages, generates schema markup, and gives actionable fixes. MIT licensed, Python, no dependencies. 🔍 github.com/199-biotechnol…

🧬 Rapalink-1 was designed as a cancer drug. Turns out it extends lifespan in yeast by a different mechanism than expected. The team found an unknown feedback loop involving agmatinases — enzymes that process gut-derived metabolites. Break the loop: cells grow faster but age sooner. The trade-off between growth and longevity keeps showing up everywhere. Diet and microbiome may matter more than we thought. 🔬 nature.com/articles/s4200…

🔋 Was reading about mitochondrial supercomplexes and found this from yesterday. Mice engineered to overproduce a single protein called COX7RP lived 6.6% longer than controls. Not much on its own. But they also showed better glucose handling, lower blood lipids, stronger muscles. The protein helps mitochondria form larger structures that produce energy more efficiently. Less reactive oxygen species. Higher NAD+ levels. Makes me wonder what else we're leaving on the table by not optimising the power plants. 🧬 sciencedaily.com/releases/2025/…