Maddy Smith

Nice to see our paper out in @SciReports. We used data from two weight loss trials (@ByBandSleeve and the Diabetes Remission Clinical Trial) to explore the effects on circulating proteins. nature.com/articles/s4159… 1/4

I wrote a blog post about my experience attending and presenting at #EASD2023 this month! Read it here: ieureka.blogs.bristol.ac.uk/2023/10/25/eas…

We had a wonderful array of discussions today at our Standing up for Science workshop! Thank you for your expert insights and advice for ECRs @Jackstilgoe @profmarkmaslin @rozeggo @RachMBuch @anjahuja @FrancaDavenport @prateekbuch @PhysicsNews @LeonieC senseaboutscience.org/voys/workshops/

Delighted to see our work on the metabolic features of genetic liability to type 2 diabetes and coronary artery disease published in @eBioMedicine today! @joshuaa_bell @emmylooroll @caroline_bull @ECSanderson @mendel_random @mvholmes thelancet.com/journals/ebiom…

Excited to see this paper now published in @JTHjournal doi.org/10.1016/j.jtha…

Enjoying sunny Edinburgh and the @megukepi conference. Great talk from @EpiHazelwood on weight loss and colorectal cancer risk and @maddy_epi talking later about weight loss and the metabolome!

PhD student @maddy_epi will be presenting her research about the long-term metabolomic effects of bariatric surgery, which uses samples from BBS participants, at the @megukepi annual meeting in Edinburgh next week.

Our data note describing the inflammation proteomics dataset measured by @OlinkProteomics in 9000 @CO90s participants is now out in @WellcomeOpenRes doi.org/10.12688/wellc… 1/3

Glad to see our study exploring the effect of COVID-19 on platelet function as a preprint! Link: biorxiv.org/content/10.110… 1/6

I'm glad to announce that our polygenic score-metabolite atlas has been published on @eLife 🥳 This atlas contains associations between 125 PGS for complex traits and 249 NMR-derived metabolic traits from up to 83,004 individuals in the UK Biobank. elifesciences.org/articles/73951

New #OpenAccess paper published using @CO90s data: #SocioeconomicPosition & #AdverseChildhoodExperiences as risk factors for health-related #BehaviorChange & #EmploymentAdversity during #COVID19pandemic @maddy_epi published in @BMC_series @BioMedCentral bit.ly/PaperC2685

We have another great talk this month in @DEMONNetworkUK biomarkers working group. @maddy_epi and Hannah Compton will be telling us about Metabolomic signatures of genetic liability to Alzheimer's disease. Wed 10am BST.

📣 New paper out now in @JAHA_AHA! 📣 We show that drinking alcohol during pregnancy is associated with a lower risk of hypertensive disorders of pregnancy (HDP) ... and explain why we *don't* think this reflects a true causal effect 🤰🍷 (1/4) #d21835506e145d21835506e288" target="_blank" rel="nofollow noopener">ahajournals.org/doi/10.1161/JA…

Our results highlight the economic adversity experienced by those with a history of ACEs during the lockdown measures (job loss, furlough etc.) - few interventions currently target this group and lockdown may have exacerbated their needs. 3/3

We used ALSPAC data (@CO90s) to look at the effects of low socioeconomic position and a history of adverse childhood experiences (ACEs) on young adults' lives during the first UK lockdown back in March 2020 2/3

Today I'm celebrating the publication of my first first author paper! This project doubled as an intro to epidemiology for me and I learned so much from my fab supervisors on this one - thank you @laurahowe_epi @AnnieSHerbert @ammhughes rdcu.be/cWgOa 1/3

Fab few days in Paris at #IGES22 with a lovely bunch of people. Especially enjoyed presenting my reverse-MR work at the poster session this afternoon 🧬

Such a great cohort of @mrc_ieu PhD candidates, well done at #IGES22! @FMBerstein, @Ciarrah_, @HelenaUrquijo,@marina_vab, @_andreicon, @maddy_epi, Panagiota Pagoni, Genevieve Leyden. And Drs @Nancymc31 and @jamesyrmsk

@_benbroadway 👏🏻👏🏻👏🏻

Four years ago I started working in the USA at Mayo clinic as an undergraduate student. This week I am happy to share my major work has just been published! #Mitophagy #PD #PINK1 #PRKN mdpi.com/2073-4409/11/1…

Finally: causal estimates for adiposity & metabolomic traits at scale! Pleased to share the first large-scale comparison of conventional vs MR approaches in UK Biobank in @LancetRH_Europe sciencedirect.com/science/articl… Key takeaways: