Niklas Lang

Very excited to share that our paper (and my MD thesis work) on perturbational single cell genomics to study early stage pulmonary fibrosis is now published in Science Translational Medicine!!! 👉 bit.ly/3Nee3Au @ScienceTM Great teamwork with co-first @schniering_j

1/n Using snRNAseq we identify a previously undiscovered population of alveolar epithelial cells in IPF - Alveolar Intermediate (ATi) cells - they share features of ATI, ATII and Aberrant Basaloid cells but also have their own distinct features. #ATi biorxiv.org/content/10.110…

Huge milestone today: thesis submitted 🎉 @LMU_Muenchen @HelmholtzMunich — and first day of clinical training @UniSpitalBasel! Grateful and excited for what’s ahead 🙌

@NeBanovich Adding this cool preprint from the labs @IPFdoc and @alisonejohn to this collection of IPF spatial trancriptomics papers: biorxiv.org/content/10.110…

Just stumbled across this super impressive preprint from @NeBanovich's Lab - which must not be missing from this collection - Particularly impressed by how they provide a spatially-resolved model of disease progression over time - definitely worth a read! biorxiv.org/content/10.110…

Two exciting spatial transcriptomics papers mapping the altered cellular landscape in Pulmonary Fibrosis in @NatureBiotech and @ScienceAdvances - they have been around as preprints for some time, but just stumbled across them today. #CureIPF Details below👇

Exciting paper in @NatureCVR: venous ECs branch and differentiate into capillary ECs to regenerate the alveolar gas exchange unit following lung injury - but NOT in fibrotic (KRT5+) or AT1 depleted regions - some food for thought: nature.com/articles/s4416…

I joined BlueSky - please follow me there bsky.app/profile/niklas… Let’s build a thriving single cell & lung biology community there! 🫁💪

I am now also on bluesky: bsky.app/profile/lukash… Trying to rebuild my network there now...

@LungHealthMUC @wordybiologist @CPC_Imaging Congratulations Kevin, amazing 🤩 🥳

Can AI help in efficiently developing therapeutic compounds against #lungfibrosis? With the ”Add-on Fellowship for Interdisciplinary Life Sciences” from Joachim Herz Foundation, Kevin Merchant (@wordybiologist) wants to find out! Bravo to the PhD in @CPC_Imaging group at LHI!

Last day on the wards as a med student! Now, time to focus on finals so I can return as a physician soon :) Grateful for all I’ve learned during my elective year in Zürich & Basel 🙏 Plus, I got to share some magic moments with old and new friends high up in the alps! 🇨🇭🏔️

@jonas_schupp @KaminskiMed @EuroRespSoc @Jannik_Ruw Congratulations Jannik!

@KaminskiMed Another proud sciency Granddad moment? Winner of this years @EuroRespSoc Science Slam: @Jannik_Ruw ! 🎉🎉🎉 Sarcoid Granuloma formation explained by Swifties Fan Types!

@ie_fernandez @ERC_Research @HelmholtzMunich @LungHealthMUC @LMU_Uniklinikum @MCSP_LMU @LMU_Muenchen Congratulations Isis, that’s so awesome and exciting!

🌟Exciting news!🌟 Proud and grateful to @ERC_Research for funding my #ERCStG #OMEGA with 1.5M€. This will enable us to discover targets to prevent pulmonary fibrosis progression and #CureIPF. #CPC-M #DZL @HelmholtzMunich @LungHealthMUC @LMU_Uniklinikum @MCSP_LMU @LMU_Muenchen

Super excited to share our latest work on immune-epithelial interactions in lung fibrosis post COVID-19! This would not be possible without the invaluable help from all the co-authors and our collaborators - Thank you! Read below for more info! nature.com/articles/s4158… (1/11)

@schniering_j Sooo cool, congratulations Janine!!! 🎉👏

🚨Check out our recent study in JCI Insight, where we used an integrative radioproteomics approach to show that CT-based delta radiomic profiling can noninvasively stratify molecular responses to antifibrotic treatment in pulmonary fibrosis. #PulmonaryFibrosis #Radiomics

I'm stoked to announce our new end-to-end framework for perturbation analysis! Our scverse advisory committee highlighted that a maintained and well-documented framework for perturbation analysis is missing. Pertpy is our attempt to satisfy this request biorxiv.org/content/10.110…