Oscar Harari
146 posts
Oscar Harari
@omharari
Associate Professor of Psychiatry at @WUSTLmed
St. Louis, MO, USA Katılım Mayıs 2010
415 Takip Edilen376 Takipçiler
Oscar Harari retweetledi
Using snRNAseq to understand the genetic architecture of rare & common variants for AD @WUADRC @alzassociation @omharari @B_A_Benitez @SFYou614 @CZI science @NIHAging nature.com/articles/s4146…
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Oscar Harari retweetledi
The #alzheimersdisease risk gene MS4A4A regulates an anti-inflammatory subtype of microglia. @wustl ow.ly/IOV250N8pNh
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Oscar Harari retweetledi
This was an amazing collaboration with @FabiaFilipello @MartinUCSF @LauraPiccio @WUADRC @B_A_Benitez @omharari and other Twitterless friends
GIF
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Oscar Harari retweetledi
this is a super cool resource....
Aligning Science Across Parkinson’s@ASAP_Research
📣 Announcing a new GP2 training resource: GP2 Bioinformatics Training Workshop. Offering a comprehensive introduction to Terra for data analysis using the latest GP2 release (version 2.0). Sign up for access to the GP2 Learning Platform: gp2.org/training/
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Oscar Harari retweetledi
Congrats @joeddougherty and @gurnett_c! We agree whole-heartedly that IDDRC@WUSTL couldn't have chosen a more fearless co-leader!
WashU Medicine Genetics@WashUGenetics
IDDRC@WUSTL announces Dr. Joe Dougherty (@joeddougherty, @CarpeRibosomam) will serve w/ Dr. Christina Gurnett @gurnett_c as it Co-Director. Congratulations, Joe, & well-played, IDDRC@WUSTL, in selecting Joe to co-lead w/ Chris. Quite a dynamic team you've put together! @WUSTLMed
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Oscar Harari retweetledi
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance nature.com/articles/s4146…
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Oscar Harari retweetledi
Check out our newest pre-print led by @FabiaFilipello. We find lysosomal defects in iPSC microglia and brain tissue from TREM2 Q33X patients @WashUNeurology @WashUONR @cziscience @WUADRC medrxiv.org/content/10.110…
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I am thrilled to share that I have been promoted to Associate Professor and granted tenure at @WUSTLmed. Special thanks to my mentors, colleagues and lab members; I couldn’t have done this without you.
I am excited to continue contributing to the understanding of Alzheimer.
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Oscar Harari retweetledi
Divergent transcriptional regulation of astrocyte reactivity across disorders nature.com/articles/s4158…
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Oscar Harari retweetledi
NEW: Single-cell transcriptomic profiling of human blood from new-born, healthy young and old, and frail adults unveils frailty-specific immune cell characteristics with genetic signatures and regulatory molecules that underlie aging doi.org/10.1038/s43587…
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Oscar Harari retweetledi
Single-cell analyses help scientists identify how cells and their interactions with each other change as #alzheimersdisease progresses. @adpdnet #ADPD2022 ow.ly/cnsY50IFLIr
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Oscar Harari retweetledi
The cellular crosstalk in Alzheimer's work we presented at #ADPD2022 was highlighted in @alzforum!
Pre-print coming out soon.
@omharari @Neuro_Genomics
alzforum.org/news/conferenc…
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Oscar Harari retweetledi
In 2018, we developed mux-seq and demuxlet to enable population-scale single-cell sequencing. Today, excited to share our paper in @ScienceMagazine where we deployed mux-seq to profile 1.2M immune cells from 162 lupus patients and 99 healthy controls: science.org/doi/full/10.11…. 1/n
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Oscar Harari retweetledi
Epic day! @AOuellette90 submitted revised F31 and manuscript, oh and I was officially promoted to Full Professor! Both Andy and I want to thank @KaczorowskiLab, @KMS_OConnell, and his amazing committee members @ErikBloss @RBurgessLab and his amazing mentor @HadadNiran @jacksonlab
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Oscar Harari retweetledi
A new #WashUMed study points to possible new therapy avenues for Alzheimer’s and related disorders.
“Our study gives evidence that targeting inflamed astrocytes and brain inflammation may be the key.”
@WashUNeurology @karchlab @ScienceTM
medicine.wustl.edu/news/new-strat…
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Oscar Harari retweetledi
(1/n) This thread will describe recent advances in life-long learning (LL) as an essential player in the current single-cell atlases. LL in this context means building a map, and iteratively updating it with new data.blob,
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