Harsh shah

🔥 A new study found that prolonged treatment with the #GLP1 receptor agonist #semaglutide doesn’t just reduce food intake—it reshapes how animals eat and how their #metabolism adapts across distinct stages of #weight change. medschool.vanderbilt.edu/basic-sciences…

Prolonged Semaglutide Treatment Reveals Stage-Dependent Changes to Feeding Behavior and Metabolic Adaptations in Male Mice Read here ➡️ doi.org/10.2337/db25-0… @AmDiabetesAssn @ADA_DiabetesPro @ADA_Pubs

Last week, Pennington Biomedical hosted the #NIDDK Clinical Methods for Nutrition and Obesity Research Course—four intensive days with some of the brightest postdoctoral fellows and early career investigators from across North America. Participants from Harvard, Columbia, Vanderbilt, University of Toronto, and 13 other institutions received hands-on training in state-of-the-art methodologies, including body composition assessment, hyperinsulinemic clamp protocols, metabolic chambers, and exercise testing. Training the next generation is core to our mission at Pennington Biomedical. These hands-on methods, from metabolic chambers to clamp studies, require world-class facilities and experienced mentors willing to guide emerging investigators. I'm proud of our faculty for sharing their expertise with this exceptional group of early-career scientists. Thank you to Dr. Leanne Redman (course director), Dr. Eric Ravussin, Dr. Steven Heymsfield, Dr. Corby Martin, and our entire faculty team, who made this possible. With #obesity and #metabolic disease rising worldwide, investing in research capacity has never been more important. #ObesityResearch #NutritionScience #ResearchTraining #ScientificEducation #MetabolicHealth

Semaglutide versus caloric restriction-induced weight loss: insights into effects on skeletal muscle mass and function "...suggests that the loss of muscle function and mass during treatment is not unique to GLP-1RA pharmacology but rather reflects the biology of caloric restriction, and these deficits can be reversed upon weight regain." physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

@omsinghneurosci @TheBurro34 @ObesityWeek @Diabetes_ADA Thank You, Om!

@TheBurro34 @ObesityWeek @sharshj @Diabetes_ADA Congratulations

Proud of lab folks at ⁦@ObesityWeek⁩ part 2. Next up ⁦@sharshj⁩ talks about the metabolic and behavioral changes during prolonged semaglutide treatment. Fun fact, his manuscript on this work was accepted in ⁦@Diabetes_ADA⁩ during his presentation!

Proud of lab folks at @ObesityWeek First up was @ritikaragwho presenting her work on contributions of mTORC1 in POMC neurons to the weight loss effect of semaglutide.

Proud of lab folks ⁦@ObesityWeek⁩ part 3. Gai-Linn Besing presents a poster and talks about her work on dietary effects on liraglutide weight loss effectiveness via FGF21.

@omsinghneurosci @ZigmanLab Congratulations @omsinghneurosci

Our new paper, “Temporal control of eating and body weight by GHSR-expressing SCN neurons,” has just been accepted in Cell Reports! 🎉 Grateful to my mentor Dr. Zigman (⁦⁦⁦⁦@ZigmanLab⁩ ) and all Zigman Lab members who made this possible. #CellReport

Chronic semaglutide treatment reveals stage-dependent changes to feeding behavior and metabolic adaptations in male mice dlvr.it/TMBdMj

Join The Obesity Society’s Neuroscience Section on Wed, Aug 28 at 1pm ET for a webinar on Bridging research and clinical care in obesity science. Register here: obesity.org/about-us/neuro… #obesityresearch #TOS2025

Honoring the late Prof. David Wasserman, pioneer of #metabolism research. “We thank David for his significant contributions as a colleague, trusted advisor, and friend,” said John Lighton, Sable Systems Founder and President. ow.ly/EXIz50Wq5cM #Insulin #Exercise #Diabetes

We are having summer potluck this year. Bring your favorite cultural food and share it with everyone. We will have drinks, snacks, and fun games to play.

Let's talk about energy allocation, also known as energy partitioning! Relevant to any animal that controls its body temperature, such as us, (most) other mammals & (most) birds. Broadly speaking, there are three different energy allocation priorities. Let's start! 1/ 🧵👇

Last week we honored the legacy of David Wasserman with a symposium featuring 4 fantastic speakers - ⁦@Hughey_Lab⁩, Darleen Sandoval, ⁦@Kang_Lab⁩, and ⁦@Isotopomer⁩. We learned, we laughed, and we remembered our dear friend and colleague.

Please join us in Nashville on June 13th as we honor the life and contributions of Dr. David Wasserman. Registration for this event is open until May 2. Please follow the redcap link below to register.

Please join us in Nashville on June 13th as we honor the life and contributions of Dr. David Wasserman. Registration for this event is open until May 2. Please follow the redcap link below to register.

@DeotaShaunak Very interesting! Congratulations, Shaunak.

Happy to share that our review on accounting for time-of-day effects to improve reproducibility and clinical translation of metabolic research is out now! nature.com/articles/s4225…

We are thrilled to invite you to the 2025 Annual VIRAL #Research #Symposium. Registration is open now redcap.link/lgcrd0af A generous travel award for all winners. See the important deadlines below. Join us to network, share your career experiences, and support @Vandy_VIRAL

Huge appreciation to all grant agencies that started to fund my work last year including Diabetes Action Foundation & Alzheimer’s Association, and the latest fund from American Heart Association to study the role of branched-chain amino acids (BCAAs) in food reward and appetite.