Sophie Paczesny

@jclinicalinvest @MedUnivSC Proud of this collaborative study, now in print @jclinicalinvest (w/cover) BIOPREVENT is a tree-based #machine learning algorithm using clinical parameters and #Biomarkers to predict chronic #GVHD. A shiny app is available @NMDP and @CIBMTR

Predicting chronic graft-versus-host disease (#GVHD) This issue’s cover features work by Sophie Paczesny @sophpacz & team @MedUnivSC on BIOPREVENT, a tree-based machine learning algorithm developed using data from 1,310 recipients of hematopoietic cell transplants: doi.org/10.1172/JCI195… In the image, blue lines represent input clinical and proteomics data, green leaves represent the markers selected from the tree-based machine learning approaches, and the red sky represents active chronic graft-versus-host disease. Image generated using OpenAI’s DALL-E 2 and edited in Adobe Illustrator.

JCI - The BIOPREVENT machine-learning algorithm predicts chronic graft-versus-host disease and mortality risk using posttransplant biomarkers jci.org/articles/view/…

Congrats on all the journey and your professorship

Coffee break #Tandem2026 is great for catching up with friends @sophpacz @ASTCT

BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

It's the sixth most frequent type of cancer in the US, and treatments are still limited. But Hollings researcher Sophie Paczesny, Ph.D. is hoping to change that. Thanks to @ABCNews4 for sharing this important work. bit.ly/450fV7U

Thrilled to see our mechanistic work published in a high impact journal. A lot of effort from great post-docs went into this- proud of what we achieved.

ST2/IL-33 axis blockade inhibits regulatory T cell cytotoxicity towards CD8 T cells in the leukemic niche nature.com/articles/s4146… @NatureComms @sophpacz

Really proud of this collaborative work nature.com/articles/s4146… @NatureComms @muschollings @IUMedSchool

Thank you ⁦@ASTCT⁩ for the spotlight and all the inspiring women that inspired me along the way. astct.org/Nucleus/Articl…

We are excited to honor the incredible physician-scientist ⁦⁦@KimrynRathmell⁩ with ⁦@AmericanCancer⁩ most important award. Her passion to combine science and care to improve patient outcomes with #kidneycancer is an inspiration to us all pressroom.cancer.org/2025MedalofHon…

As #ASH24 comes to an end, I bring you the annual door drop waste photo. @ASH_hematology, stop this immense waste!!!!

2024 National GVHD Symposium at UPMC Assembly, Pittsburgh, PA. Great science, great gatherings. Thank you Cowden family for doing this now 14th year in the row for our patients and for our medical community.

Created with content from our Best of CAR T at #Tandem24 webinar series, this infographic features key tips for outpatient #CARTcell therapy. View the full series of infographics: ow.ly/wcGC50T6EHQ

Exciting day at ASTCT HillDay advocating on behalf of patients and caregivers. Many thanks to Senator Graham and his team for their support for NIH funding! ⁦@ASTCT⁩ ⁦@LindseyGrahamSC⁩ ⁦@muschollings⁩

Great meeting for ASTCT HillDay with staff of Senator Tim Scott’s team regarding access for cell therapy for pediatric cancers and gene therapy for sickle cell anemia. ⁦@ASTCT⁩ ⁦@SenatorTimScott⁩ ⁦@muschollings⁩

Thank you @SenatorTimScott for supporting the Accelerating Kids’ Access to Care Act. We look forward to working with your team on a future bill for Individuals over 21. #astcthillday

@ASTCT @AtriumHealthWFB @AtriumHealth #ASTCTHillDay Advocating for Accelerating Kids Access to Care - streamlining access to care #AKACA and #ABC Alleviating Barriers to Care.

#ASTCTHillDay Advocating for Access to Transplantation and Cellular Therapy

ASTCT board president @DrCCutler and board member Alan Hanash meet with @SenSchumer staff to discuss Accelerating Kids’ Access to Care Act and other key issues.