Steve Fletcher

@leecronin luck?

The great asset of any thinker is the ability to criticize any given position to make progress. Critical thinking, argument, problem solving, actively trying to disprove a position is the best way to make progress the ground truth & problem solving.

@qikipedia this needs units...

People who drink bottled water every day are consuming 90,000 more plastic micro particles than those who don't.

@DirkTrauner my car burned that this morning

What makes Organic Chemistry so awesome? That after ONE lecture on the rules you can design a molecule that is stable, could be made, but has never been made.

We are looking for a talented student to fill the final Ph.D. training position in the CATALOOP network. See details here: Jobs and Career Opportunities in Europe | EURAXESS euraxess.ec.europa.eu/jobs/393977

@MoranLabChem @awhspeed he probably used a key word sometime - described getting 'white' crystals or something

@spfletcher @awhspeed Alex is a celebrity, don't you know?

for some reason, i got notifications that pie*s m*organ, t*mmy fu****ng Ro*inson (of all people) and @awhspeed posted - wtf?

It took us ages to figure out how to do this - the key was using a ligand based on Carreira’s ligand, but with a stereogenic P-centre

Divergent contiguous stereocenters via asymmetric conjugate additions ... sciencedirect.com/science/articl…

Conclusions [to my last scientific paper] 1/6 If I could transport my understanding of basic kinetics forty years back, I would have been a much better synthetic chemist. As a synthetic chemist, selectivities are merely ratios to be optimized, but as a kineticist they are parallel reaction pathways that may have different concentration dependencies at critical branch points. Truly gifted synthetic chemists like E. J. Corey, David Evans, and Clark Still displayed unique understandings of physical principles underlying their methods and syntheses. I have asserted repeatedly to my students, but not publicly until now, that the bifurcation of physical organic and synthetic organic chemistries into separate disciplines driven by pressures to specialize has weakened both fields. Of course, physical organic chemistry felt the pain first as the organic community at large lost interest in the problems they were pursuing and defunded much of it. Decades later the relentless quest of synthetic chemists to finish the large molecule or attain the high enantioselectivity undermined the patience required to probe the underlying first principles. My early critics were also right, however: a decidedly mechanism-driven approach to method development can coexist with, but not easily compete with, empiricism.

@Avis is @ToAviss_Cs legit? I think they are trying to scam me

Hi @Avis in Spain - flat tire. Your rental car has no spare. The roadside assistance guy couldn’t fix it, so he called a truck to take it away. The phone numbers I’ve been given don’t work until Monday. What should I do?

@ToAviss_Cs Thanks

@DumeleLab Somehow I never knew about this and my lab is next to his and we eat lunch together regularly

Could not believe my eyes. Cyclocarbon in solution. 👀

The SPEAKER implies. The LISTENER infers. The DUDE abides.

The abstract deadline for BSOC 2025 is approaching on September 1, 2025! In order to not miss a chance to present an oral or a poster presentation, please ensure your abstract is submitted before the deadline. For any questions please contact us at bsoc@ualberta.ca

Graduate students Lecture or poster at the 39th Annual RSC Heterocyclic and Synthesis Group Postgraduate Symposium Thursday 18 Sept 2025 in Oxford 8 lectures by final-year postgraduate students Attendance is free (registration mandatory) rsc.org/events/detail/… Please share

We have an opening for a PDRA in my group working in membrane supramolecular chemistry as part of an ERC funded project. Available from October 2025. my.corehr.com/pls/uoxrecruit…

lab clean up day

We’re looking for motivated candidates for Master's, PhD and postdoc position with organic chemistry background to join our research group ASAP!👩‍🔬 Interested candidates please send your CV, grades & motivation letter to marek.group@technion.ac.il #OrganicChemistry #Technion⚗️🔬

Ligand-enabled override of the memory effect in Rh-catalyzed asymmetri... sciencedirect.com/science/articl…