Jonathan Swerdlin

@adrian_horning_ @function Long live Adrian.

@swerdlin @function Thank you very much brother 🙌 will schedule an appointment

Looking for recommendations in Austin for a comprehensive executive health checkup. Like a place that takes my blood, checks my stress, testosterone, checks if I have cancer, etc Any places you'd recommend?

@chooserich Long live Nick.

Update: NO CANCER VISIBLE!! I still have treatment for the coming months BUT this is literally the best outcome you can have!

@DStoddardIPA @MirageRC3 @Polymarket @function has not yet found a reliable microplastics test. Stay tuned.

@MirageRC3 @Polymarket Ha! You had me running to the Function Health website to check if they test for it. Unfortunately, while they do test for some environmental toxins, they don't test for micro plastics.

NEW: Microplastics were found in 84% of heart attack survivors, compared with 32% of those with healthy coronary arteries, study finds.

Indeed @function includes 160+ lab tests like ApoB, lipid particle size, full hormone panel, etc. Ezra is now part of Function so we offer an Annual MRI that scans for major cancers, aneurysms, strokes and more in 22 minutes across 200 locations for $899. We also make low dose Chest CT’s available that deliver a calcium score for your heart and can scan for lung cancer.

@grok @FrancisPSantora @Neko @lightspeedvp @tferriss @AriEmanuel @rajshamani CAC for sure, ApoB and testosterone are other gaps to fill. I was looking at @function as a complementary option

We've raised a $700M Series C, led by @lightspeedvp and co-led by O.G. Venture Partners. Since 2023, more than 350,000 people have signed up for a Neko Health Scan, and 100,000 people have experienced one. Today, our approach to redefining how people understand and act on their health is already working: for returning members, our data shows that 5 out of 7 of their key health markers showed statistically significant improvement between scans. This funding will scale our research into the hidden causes of disease and the development of proprietary technology to detect it before it has time to develop. It will also fund our continued expansion, including to the US, where our first clinic is set to open in New York this year. This round comes weeks after our biggest update yet to the Neko Health Scan, with body composition measures and clinician review of wearable data now included in all scans across our clinics in the UK and Sweden. We're grateful for the continued support of @atomico, @generalcatalyst, and Lakestar, and welcome new investors including Liberty City Ventures, Positive Sum, and BDT & MSD Partners.

@octal @SimoneSyed @function Coming soon to all.

@SimoneSyed @function Wow, didn’t know they would do house calls.

Insanely, @function came to the house and collected 24 vials of blood in *6 minutes* and that was incredible work!!

For Tova, every birthday past 39 is a milestone. That's the age her father died of cancer. Every year since has felt like both a gift and a reminder: never take your health for granted. That's why she gets an annual MRI. Because the goal isn't simply to live longer. It's having more time with the people she loves. Now available to all Function members in 200+ locations.

@MarieForRI @patrams11 @GeriPerna @function @MarieForRI love to chat about @function and how powerful it is for your many thousands of constituents that trust it.

@patrams11 @GeriPerna @function I am unfamiliar with "function"? Traveling out of state is impossible for many, esp seniors. Pls private msg me here or email contact@marie4ri.com with details. HC access and affordability are a primary of my legislative work. I look forward to hearing from you.

My guy just told me about this insane price difference for his labs: 11 tests—Quest Diagnostics was $530, LabCorp was $503, but OYL (Own Your Labs) only charged $180. Same exact tests, but a fraction of the cost. If you need labs, you have to check this out—such a game-changer!!!!!! STOP PAYING RIDICULOUS PRICES FOR YOUR LABS!

@crossjj18 @PeterDiamandis @function for annual labs, chest CT, and annual MRI.

@PeterDiamandis What kind of test do you suggest? Bloodwork? Some type of scan? Thank you sir

When it comes to your health, you don't feel cancer until it's stage three or four. Just because your body feels fine, it doesn't mean it's fine. Get checked yearly!

@afshineemrani @function tests each of these every year for everyone.

I'm a cardiologist. After 40, stop guessing about your health. These numbers tell you whether you're building a long, vibrant life — or quietly declining without knowing it. I run these on myself. I run them on every patient I care about. Most are cheap bloodwork. All are available now. And together, they paint a picture no standard annual physical will ever give you. Print this. Bring it to your next appointment. Your 60-year-old self will thank you. ꟷꟷꟷ 𝗙𝗮𝘀𝘁𝗶𝗻𝗴 𝗜𝗻𝘀𝘂𝗹𝗶𝗻 Target: below 5 μIU/mL. Ideal: 3-4. This is the 10-year warning bell your standard panel completely misses. Your glucose and A1c can look "normal" for a decade while your pancreas is working overtime to keep them there. Fasting insulin catches insulin resistance 5-10 years before your A1c moves. By the time A1c rises, the damage is already extensive. 𝗛𝗢𝗠𝗔-𝗜𝗥 Target: below 1.0. Calculated from fasting insulin and fasting glucose. The single best measure of insulin sensitivity. Above 1.0 and your metabolism is already under strain. Above 2.5 and you're insulin resistant — even if every other number looks fine. 𝗛𝗯𝗔𝟭𝗰 Target: below 5.4%. Not below 5.7% — that's the threshold where medicine calls you "prediabetic." By then you've been metabolically compromised for years. Optimal is below 5.4%. Blood sugar mastery is longevity mastery. 𝗧𝗿𝗶𝗴𝗹𝘆𝗰𝗲𝗿𝗶𝗱𝗲 : 𝗛𝗗𝗟 𝗥𝗮𝘁𝗶𝗼 Target: below 2. Ideal: below 1. Your metabolic health crystal ball. This ratio predicts insulin resistance, cardiovascular risk, and metabolic syndrome better than any single lipid number alone. A ratio above 3.5 is a red flag regardless of what your total cholesterol says. 𝗔𝗽𝗼𝗕 Target: below 80 mg/dL for moderate risk. Below 60 for high risk. I've written about this extensively. ApoB counts every atherogenic particle hitting your artery walls. A 2024 analysis found 54% of patients had dangerous levels that standard LDL testing completely missed. If you only know your LDL, you're driving with one eye closed. 𝗟𝗽(𝗮) Test once in your lifetime. 100% genetic. 1 in 5 Americans are elevated. Triples heart attack risk independently of everything else on this list. Diet and exercise cannot lower it. The 2026 ACC/AHA guidelines now recommend everyone be tested. Most never have been. 𝗵𝘀-𝗖𝗥𝗣 Target: below 1.0 mg/L. You can have perfect cholesterol and inflamed arteries silently preparing to rupture. hs-CRP measures the fire behind the plaque. The JUPITER trial proved that finding and treating inflammation saves lives — even when lipids look fine. If this number is elevated, your mouth, your gut, your metabolic health, and your visceral fat are the first places to investigate. 𝗩𝗶𝘁𝗮𝗺𝗶𝗻 𝗗 Target: 50-80 ng/mL. Not the bare minimum of 30 your doctor accepts. Suboptimal vitamin D is linked to higher inflammation, weaker immunity, increased cardiovascular events, worse mood, and poorer outcomes across nearly every disease I treat. Supplement D3 with K2 — without K2, calcium deposits in your arteries instead of your bones. 𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 (𝗧𝗼𝘁𝗮𝗹 + 𝗙𝗿𝗲𝗲) Men: optimal range 600-1000+ ng/dL total. Declining testosterone is an independent predictor of cardiovascular death in men. It's tied to insulin resistance, arterial stiffness, visceral fat accumulation, and systemic inflammation. DHEA-S drops 10-20% every decade after 30. Tracking these isn't about vanity — it's evaluating your body's systemic resilience. 𝗕𝗹𝗼𝗼𝗱 𝗣𝗿𝗲𝘀𝘀𝘂𝗿𝗲 Target: below 120/80. Aim closer to 110/70. Every point above optimal is cumulative arterial damage. Buy a home cuff. Measure morning and evening, seated quietly for five minutes, arm at heart level. White-coat readings in the office miss what's really happening. The smartest $40 investment in cardiac self-care. 𝗩𝗢𝟮 𝗠𝗮𝘅 Men over 40: above 40 mL/kg/min. Women over 40: above 35. Cardiorespiratory fitness is the single strongest predictor of all-cause mortality — stronger than smoking, diabetes, or heart disease as individual risk factors. A landmark study in JAMA found that extreme fitness was associated with the lowest mortality with no upper limit of benefit. You can estimate VO2 max with a timed mile, a rower test, or a wearable. Get faster every year. 𝗡𝘂𝗺𝗯𝗲𝗿 𝗼𝗳 𝗠𝗲𝗱𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 Target: as few as possible. Every medication you're on should be earning its place. I just wrote about five commonly prescribed drugs that do more harm than good with long-term use. Bring your full medication list to every appointment. Ask: "Do I still need this?" Deprescribing is one of the most powerful and underused tools in medicine. ꟷꟷꟷ Thirteen numbers. Most available through cheap bloodwork and simple tests. Get them once or twice a year. Here's what I want you to understand: these numbers don't just tell you where you are. They tell you where you're heading. A fasting insulin of 8 today becomes diabetes in five years. An ApoB of 120 today becomes a heart attack in ten. An hs-CRP of 3 today means your arteries are inflamed right now — regardless of how healthy you feel. The standard annual physical checks a fraction of these. It was designed to find disease that's already there. This panel finds the disease that's coming — years before it arrives. What gets measured gets improved. Optimize with the foundation I write about every week on this platform: Zone 2 cardio plus resistance training 3-4 times per week. High-protein whole-food nutrition. Sleep 7-9 hours — non-negotiable. Morning sunlight. Stress management. And the targeted supplements I've covered in detail — creatine, magnesium, CoQ10, D3+K2, glycine, omega-3, psyllium husk. The breakthroughs coming in the next decade — gene editing for cholesterol, cellular reprogramming, senolytics that clear senescent "zombie" cells driving inflammation and aging, GLP-1 drugs rewriting metabolic medicine — will be most powerful for people who've already built the metabolic foundation to receive them. The future of medicine is personalized. But it starts with knowing your numbers today. Print this list. Book the bloodwork. Own the data. Prevention isn't passive. It's the most aggressive thing you can do for the decades ahead.

@zeo_ex You can also do a pTau217 blood test with @function and track it every year.

A famous neurologist says: The first sign of early dementia isn't memory loss. It's something much smaller, and it starts at age 45:

@byersblake Preach

You'll see a lot of doctors come out "against" this kind of broad screening system. They can even get quite agitated about it. This resistance stems from a well-established clinical consensus: traditional population-level imaging fails to improve health outcomes because false positives and invasive follow-ups do more harm than good. But this view suffers from an obvious blind spot. Existing studies rely on static data and completely ignore time-series imaging. And time-series is ignored because we haven't been able to afford to do high frequency imaging at population scale. Clearly, time series is going to be immensely more valuable than a single image. If you drop costs, value can go from 0 -> 1. On a more fundamental level, the argument against screening rests on an obviously false precept "More information is bad" -- just clearly untrue. More information better, you just have to interpret it correctly.

@KevinEscalera Thank you. We love having fun.

From the comments, looks like people love it too

This singing cartoon video by Function health is the wildest social ad I’ve seen in a while. It’s kinda awesome.

@Zodomo @bryan_johnson @function Function has an on demand option to test more frequently. Super easy.

I want monthly comprehensive bloodwork to see more precisely how peptides, supplements, and dietary changes impact my body. It seems @bryan_johnson's Blueprint, @function Health, and others are now subscriptions where you get 2 tests a year. Where can I get 12+/yr? These options allow for more, but they are not transparent about what one-off pricing costs, which is roughly 5/6th of what I'd be paying for.

Reposting this because I think it eloquently stated the same points I made today re: this new product vs MRI, and also because it includes the thoughts of Function’s @DanielSodickson, formerly of @NYUImaging and truly the expert’s expert on MRI.

Strong agree -- "@Midjourney's instinct is… sound: build a fast, cheap, radiation-free scanner. But the revolution isn't the snapshot; it's scanning longitudinally to detect change, fusing it with other modalities like MRI, and putting it in homes rather than spas. ... Overall, kudos to @DavidSHolz and his team"

@function estimates over 1000x growth in Annul MRI's this decade. The traditional checkup is obsolete. In the last year we've had to expand from ~30 to ~200 locations to meet demand for @function's 22-minute Annual MRI. It is now under $1,000 and scans for cancers across brain, pancreatic, prostate, uterine, ovarian, bladder, kidney, spleen, gallbladder, liver, and thyroid. Also scans for aneurysms, strokes, hernias, tears, diverticulitis, iron overload, endometriosis, abnormal cysts, fatty liver. If you add time, it scans the spine and the skeletal system. Before AI, this took hours and many thousands of dollars. The 22 minute scan time is on track to be reduced much further, and the cost will deflate with it. AI is the most important technology is medical history.

As someone who is very particular about product quality, I give @function an A+. Their customer experience is outstanding. 1) Scheduling a blood draw takes about 30 seconds 2) Results come back fast 3) The depth of insight you get into your health is on another level

@steipete @rrhoover still selling?

I'm still homeless in SF. If anyone's renting or selling a nice place, slide into my DMs. The hotel room is getting old.

@mousemastery @function @pli_cachete Long live Leah.

@function @pli_cachete i owe you my life 🙂‍↕️

The bottom line RE: “my health” is that doctors explained away my symptoms for 20 years until I paid a startup $500 for comprehensive bloodwork. I’m not saying the system’s broken but unless you know you can smash that mf $500 bloodwork button, you are a snowball in hell