The Jeremy Chase Crawford Lab

Trying out this BlueSky thing. bsky.app/profile/jcclab…

Nineteen St. Jude scientists have been named to the 2025 Highly Cited Researchers list, the most from St. Jude since the list began. This distinction identifies those whose publications rank in the top 1% for citations, indicating broad influence. ow.ly/HKIk50XrffV

As we continue making progress with the Global Platform for Access to Childhood Cancer Medicines, shipments have now arrived in Ecuador, Mongolia, Nepal, Uzbekistan and Zambia, with Jordan to follow.

Just saw a talk by @AJ_Pask at #AGBT25 #AGBTGM on marsupial genomics, evolution, and gene editing for conservation. Completely mind blowing work. Taking both genetic editing and conservation work into a new frontier.

David Altshuler from Vertex kicking things off at #AGBT25 with an amazing talk but also an inspiring thought: “I hope that ‘hope’ is something that all of the work presented here can help create.” #NIH-funded research is ultimately creating hope for the future, don’t forget it!

The JCC Lab is #hiring experienced scientists intetestd in human immunology and applied NGS assay development. These are long term, stable positions not subject to the ebb and flow of government funding. Feel free to reach out! talent.stjude.org/careers/jobs?k…

I have collected Christmas ornaments for years, but two of my close collaborators just gifted me my first JCC Lab ornament! They said it’s a rocket because “the lab is taking off”. Thanks so much @Asya_Minervina and @pogorely!!

We're looking for a talented scientist 👩‍🔬👨‍🔬to join our group @StJudeResearch! Help us develop/characterize #stemcell/#organoid models of #raredisease #epilepsy disorders. 🧠🧬🧠🧬 Details below - join us! talent.stjude.org/careers/jobs/J…

Our first official lab pic. I can't wait to see how The JCC Lab continues to grow. If you're interested in joining our team, we have open positions. tinyurl.com/jxezsb3k #Hiring #immunoinformatics

We analyzed immune memory to COVID mRNA vaccines across human tissues and found durable persistence of T cell memory in lymphoid organs and lungs with enhanced regulatory functions compared to blood. @JDavisPorada collaboration with @psimslab @Teijaro_Lab @columbia_MI

Super excited to talk to my amazing colleagues down the road. Has been a great visit to @uthsc so far!

Timescales in Cell Biology

Congrats to Dr. Jia-Hua George Qu of The JCC Lab for a great presentation on dynamics of CAR-negative T cells after infusion at the Translational Cancer Immunotherapy Retreat "Expanding Horizons in Pediatric Immunotherapy."

New paper out! Rare Coagulopathy caused by auto-abs to protein S #COVID19. Led by Nils Landegren lab @UU_University #auth-Ahmet-Yalcinkaya-Aff1-Aff2" target="_blank" rel="nofollow noopener">nature.com/articles/s4159…

Neuroimmune crosstalk directs T cell differentiation for optimal viral clearance. With our collaborators, we show that neuropeptide CGRP produced by neurons during infection boosts Th1 differentiation while suppressing Th2, via RAMP3 on T cells. @Nature nature.com/articles/s4158…

Interesting study from Norway where they enrolled people in March of 2020 prior to infection, and followed them for 22 months. Memory and concentration problems persisted after infection, and didn't attenuate with time. 1/2 ijidonline.com/article/S1201-…

What are the rules of the immune receptor code? In my talk @KITP_UCSB last Friday I summarised our recent findings, provide a perspective on why ML approaches have so far not achieved breakthrough success, and propose a path forward: online.kitp.ucsb.edu/online/viralim…

This time, we developed a nasal booster vaccine for influenza viruses. In this preprint, @MiyuMoriyama et al. show that nasal boosters with unadjuvanted hemagglutinin protein induce sterilizing immunity in mice against flu. (1/) biorxiv.org/content/10.110…

Key numbers in biology. 1/2