Kuchroo Lab

A new Science #Immunology study addresses recent, conflicting findings on the role of #IL17 in #MultipleSclerosis, showing that IL-17A and IL-17 drive disease in EAE mouse model. @KuchrooLab scim.ag/3OtoiF7

In this study led by Allen Ho, we re-affirm the critical role of Th17 cells, & IL-17A & IL-17F in inducing autoimmune neuroinflammation. Now @SciImmunology

An adaptive source of IL-17A/F is indispensable for EAE development! And B cell-derived IL-17 induces IL-23 signaling required to convert stem-like Th17 cells to encephalitogenic Th17 cells. @GeneLayInst @MGBResearchNews @HarvardMed @BroadInstitute science.org/doi/10.1126/sc…

B cells are a critical adaptive immune cell type in the development of TH17 cell–mediated experimental autoimmune encephalomyelitis @SciImmunology science.org/doi/10.1126/sc… @KuchrooLab @BrighamWomens

In this review, Adam, Suhail, Kuchroo, and Vignali highlight the challenges and novel approaches to developing agonistic inhibitory receptor (IR)-targeted therapies to treat #autoimmunity and inflammatory disorders. hubs.la/Q0493L5y0 #CancerFocus #LymphocyteBiology

Tim-3 restrains ILC2 function and attenuates airway hyperreactivity via NLK pathway @NatureComms @KECKSchool_USC nature.com/articles/s4146…

Review @JExpMed @Vignali_Lab @aamirbkbz @KuchrooLab Inhibitory receptor agonists: Emerging strategies in immune modulation rupress.org/jem/article-ab…

If you haven’t registered yet, now's the time! Some of the best minds in neuroimmunology, neuroscience, immunology + AI — in one room. RTN2026 | Oct 26–28, 2026 | Weizmann Institute conferences.weizmann.ac.il/RTN2026/ @jonykipnis @QuintanaLabHMS @stevens1lab @RejaneRua @WeizmannScience

By reprogramming the tumor microenvironment with an engineered virus, @QuintanaLabHMS boost anti-tumor immunity in a glioblastoma model @NatureCancer. @MGBResearchNews @broadinstitute @harvardmed massgeneralbrigham.org/en/about/newsr…

🔔 New episode alert! Dr. Ana Anderson (@AnaAndersonlab) from @HarvardMed talks about her work on #ImmuneRegulation in cancer. ▶️ bit.ly/3KzeIOO

Excited to share our review in @NatRevRheumatol is now online where we discuss PD-1, BTLA and TIGIT as promising agonist targets for rheumatic disease. Congrats to Naomi Goldman and Arlene Sharpe for a true team effort! #immunotherapy #autoimmunedisease #rheumatology

Review @NatRevNeurosci @OlegButovsky Immune dysfunction in Alzheimer disease nature.com/articles/s4158…

Thrilled to share our invited Nature Reviews Neuroscience review on the role of peripheral immunity in Alzheimer’s disease. Honored to write this piece with outstanding colleagues @KuchrooLab, @RudyTanzi, @weinerlabhms, Mehdi Jorfi and rising stars from my lab Neta Rosenzweig and Kilian Kleemann. My sincere thanks to Editor Katherine Whalley for the invitation. The time has come to deeply investigate peripheral immunity in AD.

Immune dysfunction in Alzheimer disease — a Review by Oleg Butovsky, Neta Rosenzweig, Kilian L. Kleemann, Mehdi Jorfi, Vijay K. Kuchroo, Rudolph E. Tanzi & Howard L. Weiner @OlegButovsky @mejorfi @KuchrooLab @RudyTanzi @weinerlabhms nature.com/articles/s4158…

Beautiful work!

🙌A huge thanks to the organizers for putting together a brilliant program for #RTN2025 🧠 - @IdoAmitLab @jonykipnis @stevens1lab @RejaneRua @QuintanaLabHMS. Also grateful to our many sponsors, speakers, attendees & vital team behind the scenes for an awesome meeting of the minds

@AnaAndersonlab @NatureMedicine @NatureComms A 🌏 #KuchrooLabReunion in Kyoto with @NorioChihara, VKK, & Kimitoshi Kimura 🇯🇵

@AnaAndersonlab @NatureMedicine @NatureComms #KuchrooLabReunion at #CSNeuroimmune25 in NYC

🧵of #KuchrooLabReunion 🌎 First up, Manu Rangachari & Gerd zu Hörste (@mzhlab), together at #MSXchange 2024 in Montreal. We love to see our alumni getting together

The Weiner Prize in Neuroimmunology has been established in honour of Professor Howard Weiner. This award will be presented at the Neuroimmunology Symposium. October 17, 2025 The Joseph B Martin Conference Center, Boston, MA. Register here🔗forms.office.com/r/bALksQghPB