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Maxine Singer, Guiding Force at the Dawn of Biotechnology, Dies at 93 nytimes.com/2024/07/10/sci… What a force she was!

Normally dormant elements in the human genome, including retroviruses, transposons and other repetitive sequences, could offer new avenues to treat neurodegeneration, cancer, autoimmunity and even aging nature.com/articles/s4158… rdcu.be/dGb8U

Great educational session at @AACR #AACR24 chaired by @KathleenHBurns @DanaFarberNews @harvardmed @broadinstitute about genomic #repeats and #transposable elements in #cancer with an epic quote from late #Nobel Prize winner Sydney Brenner

There is no one better to be than yourself!

Having benefited from excellent mentors over the course of her career, a physician concludes that a true mentor is someone who has more imagination about you than you have about yourself. Read the full Perspective: nej.md/3SDFcPf

revisiting this Clifton poem. if only more world leaders had “greater selves.” but it is up to those of us who do and are listening to continue the work

A #MethodstoWatch from @DrArunimaSingh on nanopore-based protein sequencing. There are many technical hurdles to sequencing proteins using nanopore technology, but recent developments hint that proteome-scale sequencing is on the horizon. #moty2023 nature.com/articles/s4159…

Congratulations to Stu, @bloodgenes, @danielevanbauer, @JianXuLab, and many others on this big day! 🎉

How do "molecular motors" fold the genome? A new #SciencePerspective looks at insights that are starting to yield an understanding of the mechanism by which these motors extrude loops of #DNA to structure genomes. scim.ag/4X7

My answer when people ask how my writing is going

lol

So @nanopore discovered something a few days ago - and it has to do with light. And they posted this image (sorry, too good not to share off the community). Yes, that’s 469% increased output. So, we decided to give it a shot and …

First - congrats to Arch and the Rome team - we are closely watching the dark genome story and LINE-1 Second, we cannot help but notice the role of strategic (i.e.,pharma) venture capital in keeping biotech deal flow moving. We are guilty as well these days of suggesting to target strategics for fundraising. Whatever the reason (e.g., less valuation sensitive) they are more often writing checks while institutional investors continue to resist making the capital calls ☎️ rometx.com/press-releases…

“In one of the most notable moments in sports history, Kenyan runner Abel Mutai was just a few feet from the finish line, but became confused with the signage and stopped thinking he had completed the race. A Spanish athlete, Ivan Fernandez, was right behind him, and after realizing what was happening, he started shouting at the Kenyan for him to continue running; but Mutai didn't understand his Spanish. Fernandez eventually caught up to him and instead of passing him, he pushed him to victory. A journalist asked Ivan, "Why did you do that?" Ivan replied, “My dream is that someday we can have a kind of community life where we push and help each other to win.” The journalist insisted “But why did you let the Kenyan win?" Ivan replied, "I didn't let him win, he was going to win.” The journalist insisted again, “But you could have won!”Ivan looked at him & replied, “But what would be the merit of my victory? What would be the honor of that medal? What would my Mom think of that?” Values are transmitted from generation to generation. What values are we teaching our children? Let us not teach our kids the wrong ways to WIN.” Calltoactivism

This is a letter Feynman wrote to a former student who wrote congratulating him for the Nobel. I’ve posted it before but I really find it worth it to read especially as a student or early stage research person.

1/n Our Region Capture Micro-C (RCMC) preprint by @ViraatGoel @mileshuseyin is out today in @NatureGenet at rdcu.be/dbEuM See also MIT News story at news.mit.edu/2023/unprecede… with a nice 2-min video explainer youtube.com/watch?v=oybAJI… More details below:

Science is hard. Good research makes you feel stupid. You're inadequate for the task at hand. How else would it be? You're pushing the boundaries of knowledge. Get used to it. This process is immensely rewarding.

Fly ‘em to the Moon! @NASA has named @NASA_Astronauts @Astro_Christina, @AstroVicGlover, @astro_reid and @csa_asc @Astro_Jeremy as the crew of the #Artemis II mission. Artemis II will fly the crew of four to the Moon and back to Earth! Together, we are going!

@halymordor So if u do total rna seq you won’t get jailed in Idaho?