Johnson McEvoy MSc, DPT, PT

#physiotherapy #iscp #ireland

@hjluks The effect of exercise muscle immune modulation is fascinating. Sluka’s et al work on exercise (both aerobic and strength) effect on M1 and M2 macrophahes is exciting

@PhysioMeScience No direct diet advice? Sleep? Stress? All big factors for immune, metabolic and endocrine influences

Consistency of advice for the conservative management of knee osteoarthritis across international clinical practice guidelines pubmed.ncbi.nlm.nih.gov/41183559/

@ArthroscopyJ @grandales_ramon Not to mention the risk before TKR or THR

Check out this visual abstract based on the the article by Wainwright et al : Infection rate after ACL surgery doubles with steroid injection within 8 weeks of surgery. ow.ly/MFuV50XBMF0 #Orthopedics #ACLSurgery #SteroidInjection #InfectionPrevention #Arthroscopy

@PhysioMeScience 👍🏻 As stated, it’s important not to overstate the effect size of exercise on pain… having said that, exercise is one of the best ways to improve overall health including metabolic and immune

Reframing exercise for musculoskeletal pain relief bjsm.bmj.com/content/early/…

@ksluka0101 Really great book Love the addition of your art 👍🏻

evolve.elsevier.com/cs/product/978… The third editions of my book is now available at the link above. Use discount code BAFF20 to get 20% off. Updated science, new chapters, patient stories, new case studies and my original pain-related artwork are included. #painscience #physicaltherapy

@adamdobson123 @DrMarwanAl_D Mazza DF, Boutin RD, Chaudhari AJ. Assessment of Myofascial Trigger Points via Imaging: A Systematic Review. Am J Phys Med Rehabil. 2021;100(10):1003–1014. PMCID: PMC8448923

If trigger points were real, why hasn’t any reputable ultrasound technician ever claimed to have found one? 🦄 @DrMarwanAl_D

@tomgoom @Seth0Neill @pdkirwan @DrPeteMalliaras @tendonpain @TendonGlasgow @alisongrimaldi @DakinLabGroup @Physio_lab @StephLaz_ @ExploredPhysio Including Sherhans work from Harvard over 20 years ago on lipid derived mediators… specialised pro resolving mediators from OM3’s… This work potentially could win a Nobel prize… "No matter how we twist and turn we shall eventually come back to the cell" Rudolf Virchow

@tomgoom @Seth0Neill @pdkirwan @DrPeteMalliaras @tendonpain @TendonGlasgow @alisongrimaldi @DakinLabGroup @Physio_lab @StephLaz_ @ExploredPhysio Inflammation is a first principles approach to human health and MSK pain. Mounting evidence (older and newer) that non-resolving inflammation (m1 to m2 polarisation) is a key in ongoing nociception and tissue distress. The switching depends on many factors…

Does inflammation play a role in tendinopathy? 🤔 We had moved away from it but recent research is suggesting both local and systemic inflammation may be part of the pathology. What do you think?

@PhysioMeScience Interesting test and paper… commendable 👍🏻 Suspect a significant % of cohort would not be able to perform… interesting to know how many were excluded in the trial due to inability to perform?

The Broken Wing Sign 🐦: A New Clinical Test to Detect Gluteus Medius Pathology with and without Fatty Infiltration 👇👇👇 pubmed.ncbi.nlm.nih.gov/40938961/

Just arrived in my office-3rd edition of my book. New chapters, my original art, patient stories, and case studies. Available in September....#kathleensluka #slukaart #painscience ⁦@UIowaPTRS⁩ ⁦@uihealthcare⁩ ⁦@IowaMed⁩ ⁦@UIowaNeuro⁩

@DissentingCat @Niek_NTe

@PhysioMeScience With the added caveat that the effect size on pain from exercise wasn’t outstanding and that “sham” (albeit hard to define non-specific exercises as sham) had similar outcomes to specific tendon targeted exercises. Patient expectations and beliefs play a significant role.

Physiotherapy management of gluteal tendinopathy sciencedirect.com/science/articl…

@BrandonLuuMD Om3 EPA & DHA play an important role in inflammation resolution from M1 to M2 states Resolvins, protectins and maresins Not surprisingly they show up in these studies with positive influence However study design is hard connect causation as you eloquently said

Omega-3 fatty acids reduce inflammation and improve endothelial dysfunction. A new meta-analysis linked higher omega-3 fatty acid levels in the blood to a 45% lower risk of cardiovascular death. Lets break it down🧵 1/9

@OGdukeneurosurg Crook lying position?

Positioning

@DavidPerlmutter + Omega 3 and vit D

Two supplements everyone should consider for optimal brain health: Creatine & magnesium

@Rainmaker1973 M1 Macrophage? Innocuous until they attack with cytotoxic TNF etc PAMP and DAMP activated

White blood cell wandering between red blood cells and checking for harmful organisms.

New study finds evidence for neuroinflammation in the periphery of individuals after WHIPLASH. Very well conducted study! Sample size ✅ control group ✅ Sig. findings on MRI ✅ Sig. findings on blood tests ✅ Sig. findings on QST ✅ Seriously, the notions of “brain derived pain” without nociceptive input pain are just plain nonsense and not sustainable anymore.

@Omid_HopeUni Infraspinatus upper part also shoulder abductor?

Rotator cuff muscles/tendons ☑️supraspinatus👉🏼a single tendon within a bipennate muscle ☑️subscapularis👉🏼four tendons that span the insertion ☑️infraspinatus👉🏼an oblique head (effective head depressor) & a transverse head (effective external rotator) jisakos.com/article/S2059-…

@OGdukeneurosurg Bone changes seen with CRPS?

Nerves to body: what innervates bones? What’s a disease from poor bone innervation?

@Retlouping @MoAImam 👍🏻 and muscular pain

@MoAImam Looks more like somatic referral from disc or facet rather than radiculopathy?

Typical pain patterns in radiculopathies a) C5 b) C6 c) C7 d) C8 e) T1 link.springer.com/article/10.100…