Venkat Mocherla

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Venkat Mocherla

Venkat Mocherla

@vmocherla

Building Midstream Past: @Qventus @AdvisoryBd @DaVita @a16z

San Francisco Katılım Ekim 2011
4.8K Takip Edilen1.9K Takipçiler
Dhruv Vasishtha
Dhruv Vasishtha@dvasishtha·
Any venture backed early stage startups looking for an excellent Chief of Staff. A former intern is looking, she's a strong technical AI pm wrapping up HBS and spikes on grit and getting shit done.
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Jay Rughani
Jay Rughani@JayRughani·
Healthcare is off to a wild start in 2026. On the @a16z pod, I riffed with America's favorite healthcare comedian, Nikhil Krishnan of Out-Of-Pocket, to explore what else will happen: - AI doctors going mainstream - People opting out of health insurance entirely - Weight-loss drug usage doubling - Peptide parties proliferating - Healthcare labor crisis cascading - and more... Was fun to question some assumptions underlying our healthcare system and debate how to build a better one w/ @nikillinit. 00:00 Introduction 02:15 Healthcare Predictions for 2026 08:00 Taking Healthcare In Your Own Hands 26:59 Explosion of Self Monitoring 31:38 Our Desire for Agency in Healthcare 34:42 AI "Doctors" Everywhere 41:43 Clashing Regulations, IP Battles, and Populism 46:42 How will we know AI is working in Healthcare? 57:15 AI Impact on Healthcare Jobs 01:05:39 The Human vs. AI Debate in Healthcare 01:08:52 Weight Loss Drug Ubiquity 01:17:03 The Gray Market of Peptides 01:29:23 Should We Spend More on Healthcare? 01:34:29 Content Diets in the Age of AI Slop
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Ali Ghodsi
Ali Ghodsi@alighodsi·
@fahdananta Yes, owning your own lakehouse is #12 on the rejuvenation program. It's right after collagen peptides and right before gene therapy. Reverses portfolio aging instantly.
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Fahd Ananta
Fahd Ananta@fahdananta·
The real reason Bryan is trying to live forever is because he was an early investor in Databricks and is waiting for the liquidity event
Bryan Johnson@bryan_johnson

I’m going to try and achieve immortality by 2039. One year of time passes and I remain the same biological age. I invite you to join me. The search for the fountain of youth is the oldest story ever told. It’s been the dream of dreamers for millennia but always painfully out of reach. For the first time in the history of life on earth, in just the past 24 months, the window has opened for a conscious being to realistically strive for this goal. It is an absolutely insane moment. We currently do not know how 2039 immortality will be achieved. There are new, promising therapies that can turn back the clock decades, but they’re buggy. Sometimes they mistakenly cause cancer. We gotta fix that. But we know immortality is possible because nature has already solved it. This isn’t a physics problem like trying to travel faster than the speed of light, it’s a biological engineering problem that evolution has cracked multiple times. The freshwater hydra constantly regenerates its own cells and doesn’t succumb to senescence. It is effectively ageless. The "immortal jellyfish" (Turritopsis dohrnii) can revert its cells back to a youthful state and restart its life cycle indefinitely. Lobsters produce an especially active form of an enzyme called telomerase that preserves their telomeres and keeps their DNA from degrading as they age. We need to port the software to humans. 2039 is a reasonable target because of the accelerated, AI-driven rate of innovation. AI is morphing from assistant to scientist.  It is powering current researchers with previously unimagined capabilities to enhance discovery and development. That, coupled with enhanced biomarker measurement, creates a closed-loop system of improvement that will speed things up dramatically. This is what I’ve been doing for six years. As crude as longevity technology is today, the improvements I’ve personally seen are stunning. I started as a worn-down, inflamed, aged 42 year old who’d broken himself on the rocks of American food slop and entrepreneurship martyrdom. Six years later, my body largely operates at elite 18 year old levels. That includes my cardiovascular system, fertility, strength, and hormones. Not all is well though. I have mild to moderate hearing loss in my left ear that we can’t fix and my brain is anatomically age 42 (I’m 48). Still, unreal results. My team and I did this by following the scientific method. We measured the biological age of every organ. We referenced the best scientific evidence on how to slow aging and rejuvenate.  We methodically completed these protocols and measured again. Rinse and repeat. We could do so much more and faster if we had better measurement and better therapies. Both of which are cooking all over the world right now. To speed things up now, I’m currently having thousands of Bryan Johnson organ clones built in a dish. This will allow me to test drugs and other molecules against my biology to accelerate learning and save my body from potential mishaps. Yes, we’ll make mistakes. Hopefully they won’t be fatal. And of course there’s always bad luck to contend with. But I trust in fate and I believe that destiny is going to grant the human race the pleasure of achieving the ultimate: immortality. While immortality would certainly be cool, the real (secret) objective is to focus our collective attention on a positive goal. Something that helps us feel hope and excitement for the future. I personally love the idea of having a child-like mind, 18-year-old physical vibrancy, and a lifetime of wisdom. This 2039 goal is as much about AI as it is about us humans. It’s about how we survive giving birth to superintelligence. It’s kind of a big deal. We haven’t done it before. A lot can go wrong. I figure that one of the best ways to improve the probability that we build safe AI, and don’t kill each other in the meantime, is to transform our shared aspirations from yolo to don’t die. Right now, we are a suicidal species. We do all kinds of really primitive shit. We unnecessarily kill ourselves with what we eat and how we live our lives. Companies make profits from killing other people with their products. We trash the only home we have. We celebrate these things as virtue.  It’s really fucked up and backward. Soon enough we’ll realize just how infantile we are right now. The 2039 goal points us in the right direction. To say yes to life and no to death. Defiance even. If you’re interested in doing this with me, I’ll continue to share everything I do for free. I’m also going to build this out in Blueprint. We’ll help you do exactly what I’m doing, at a fraction of the cost and effort, alongside an aligned and motivated community. I think this is the coolest goal imaginable. I find it hard to believe that of all the people who’ve lived, it’s us who get the opportunity to have this moment. I pray that we have the courage to appreciate the sacredness of our existence. I pray that we will be brave enough to defend her amidst the onslaught of all the forces that would try to end her. We don’t know, but we may be the only intelligent life to exist in our corner of the galaxy. I pray we will be warriors, caretakers and stewards of existence and honor the gift that has been bestowed on us.

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Parag Agrawal
Parag Agrawal@paraga·
just setting up my twttr, again I’ve been heads down building Parallel with some of the best people I’ve ever worked with. We’re creating infrastructure for AIs to search and use the web.
Parallel Web Systems@p0

The web’s next user isn’t human. AIs will soon use the internet far more than humans ever have. At Parallel, we are building for the web’s second user. Our API is the first to surpass humans and all leading AI models (including GPT-5) on deep web research tasks.

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Nikita S
Nikita S@singareddynm·
A million times, yes! Can’t wait to be Mrs @danielhavir 🫶
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Scott Kupor
Scott Kupor@skupor·
Thank you to @realDonaldTrump for the opportunity to serve this great country. Our future as a nation is incredibly bright, and I am humbled to be able to play a small part in helping ensure this path to further greatness!
Alex Immerman@aleximm

Hell yea @skupor! The US government is lucky to have you. Make meritocracy great again.

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Jen Kha
Jen Kha@jkhamehl·
leak to @ArfurRock, raise $, announce on @tbpn - the new capital raising media stack 🤖
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vittorio
vittorio@IterIntellectus·
absolutely incredible. a 9-month-old baby with a fatal genetic disorder was healed with the first-ever personalized gene-editing therapy. a treatment made for him alone. a therapy of one.
vittorio tweet media
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ConsultingHumor
ConsultingHumor@ConsultingHumor·
consultants when they have to answer a client question they don't understand
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Venkat Mocherla
Venkat Mocherla@vmocherla·
Andrew would be so proud of every Indian family WhatsApp group 😆
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Bill Simmons
Bill Simmons@BillSimmons·
First crazy Steph game of the season - the Warriors are back!
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Jay Alto
Jay Alto@theJayAlto·
trying is cool. ambition is cool. failing is cool. persistence is cool. learning is cool. success is cool. obsession is cool. mastery is cool. discipline is cool. greatness is cool.
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Scott Becker
Scott Becker@BKRBusinessMin·
We are releasing the webinar we did Monday with genius @vmocherla through the Becker Private Equity and Business Podcast line. Great audience and great question from the audience. Our next six weeks of webinars are fully booked. God bless America. Teach and entertain and amplify the voices and stories of great leaders and people.
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