Anusha Kalbasi

@m_rashidian1 Well-deserved Mohammad! Congrats!

Honored and deeply grateful to receive the CRI Lloyd Old Award. Thank you to the CRI for this incredible honor and to everyone who has supported our work. I hope our lab will continue advancing science that ultimately benefits patients.

@j_eyquem @CancerResearch No surprise here :) congrats Justin!

Honored to receive a CRI STAR Award! Immensely grateful to the @CancerResearch Institute for backing bold ideas and supporting our mission to decode the rules of T cell signaling and make in vivo T cell reprogramming a reality. Excited for what comes next! 🚀

Way to go Kayla, so well-deserved!

Highly anticipated data with first in class modified TIL therapy that does not use IL2, has lower dose lymphodepleting chemo - single arm ph1/2 OBX-115 in refractory metastatic melanoma #ASCO26 @DrBetofMDPhD @StanfordCancer ORR 67% w 2 CR (!!) DoR not reached (1+ to 14+m)

@Stef_Tst @DeepaRangachari @BIDMC_HOFellows @ConquerCancerFd Well deserved, @Stef_Tst !

Thank you @DeepaRangachari!! This would have not been possible without your help and amazing mentorship environment at @BIDMC_HOFellows! I'm honored to receive the support of @ConquerCancerFd as we strive to deliver new cell therapies to patients with solid tumors!

SCI member @xrtcell & others show that combining targeted #RadiationTherapy with an experimental immune-boosting drug (BO-112) & anti-PD-1 therapy before surgery may help the immune system fight aggressive #SoftTissueSarcomas. brnw.ch/21x2SeG

@Jalal_Ahmed @NatureCancer Bravo! Very nice @Jalal_Ahmed !

Thrilled to share our new paper out today in @NatureCancer: Tumor irradiation promotes antigen dressing of dendritic cells to enhance CAR T cell persistence and efficacy in lung metastases. A single dose of radiotherapy makes CAR T cells work against extensive metastatic lung cancer — even when the target antigen is also on normal tissues. nature.com/articles/s4301… 🧵 (1/14)

🚨What if we could reliably program macrophage polarization state?🚨 biorxiv.org/content/10.648… Macrophages are highly plastic immune cells that perform critical functions by polarizing into distinct cellular states. The polarization state of macrophages can substantially influences the progression of cancers, infections, and autoimmunity. (1/11)

If you haven’t REAP’d, have you really lived?

@CampKatiee @ToniRibas12 @parkerici @SWOG @SU2C @Agilent @Covaris @AACR @UCLAJCCC congrats @CampKatiee, Toni, and team!

Incredibly proud to share this work with @ToniRibas12 Thank you to all collaborators and support @parkerici @SWOG @SU2C @Agilent @Covaris @AACR @UCLAJCCC

Made possible by Marisol Quintero & team @Highlight_HLT, @theNCI, @StanfordCancer, @ConquerCancerFd, @UCLAJCCC. And most importantly, our patients. /10

Congrats to first author @JieDeng (my first post-doc, now leading her own group), UCLA Sarcoma program, and our @StanfordMed team on rich correlatives (@AasthaPal @Stef_Tst @ZinaGood @aaronmring @everettmoding) /9

Radiation is a powerful anti-cancer agent, but I considered it a weak immunomodulator. Our new study @CD_AACR changed my mind: in the right context, RT can incite potent systemic immune responses in patients (even rare irAEs). Which context? brnw.ch/21x1b6E A 🧵 /1