yunhan xu

Excited to share new validation results of our @GoogleDeepMind @GoogleAI AI co-scientist! Addressing the challenge of liver fibrosis, a condition affecting millions globally with few treatments options, we've been working with Dr. Gary Peltz @StanfordMed, exploring how co-scientist can help with identifying new therapeutic avenues for this complex disease. Specifically, we tasked co-scientist with proposing novel hypotheses for epigenetic alterations leading to myofibroblast formation in liver fibrosis, suggesting new treatments and designing experimental protocols for validation. Towards this, the co-scientist uncovered and highlighted histone deacetylation and DNA methylation, pointing towards HDAC (like Vorinostat), DNMT and BRD4 inhibitors as treatment options for study in advanced human liver organoid systems. Experimental validation by Dr Peltz's lab @StanfordMed showed HDAC inhibitor Vorinostat & BRD4 inhibitors had significant anti-fibrotic effects in the organoid models; further Vorinostat also aided regeneration and cut TGFβ-induced chromatin damage by 91%. We had previewed this work back in Feb but super glad to see comprehensive experimental validation results backing up the co-scientist generated hypotheses. Notably, this work was done with an older version of the system from last year. We have made considerable progress building on the latest Gemini 2.5 models. More soon! Bioarxiv - biorxiv.org/content/10.110… AI co-scientist - research.google/blog/accelerat… Grateful for the collaboration with Dr Peltz's team at Stanford. Work done with amazing team mates @GoogleDeepMind @GoogleAI @taotu831 @Mysiak @ckbjimmy @apalepu13 @alan_karthi @KeranRong @ynhnx and many more not active here.

@achowdhery @reflection_ai congrats, aakanksha !!

Thrilled to have joined an incredible team at Reflection @reflection_ai to push the frontier of autonomous coding!

@vivnat @Mysiak @alan_karthi @ckbjimmy @taotu831 @KhaledSaab11 @RyutaroTanno @acarroll_ATG interested? sign up to be a trusted tester! → docs.google.com/forms/d/e/1FAI…

grateful for the chance to collaborate with so many brilliant and thoughtful people on this effort, including @Mysiak @vivnat @alan_karthi annalisa pawlowsky @ckbjimmy @taotu831 @KhaledSaab11 @RyutaroTanno @acarroll_ATG kavita kulkarni, keran rong, fan zhang, alexander daryinand, and many more across @GoogleDeepMind @GoogleAI @googlecloud—plus incredible scientists at @Stanford @Sequome @imperialcollege @FlemingCentre @MethodistHosp whose partnership has been invaluable to the development of co-scientist.

*so* excited to share our team's work on an AI co-scientist—a multi-agent system that acts as a virtual collaborator for scientists, powered by gemini 2.0. blog / research.google/blog/accelerat… paper / storage.googleapis.com/coscientist_pa… couldn't have put it better than @vivnat—accelerating scientific progress and helping to cure diseases may be the most profound purpose of AI. we hope that co-scientist brings us one step closer to this aspiration.

"Computer-Using Agent" from 1994 and also it is a dog

this is how websites should look

Too excited about this bachelor party itinerary I made in LaTeX

If God didn't want me to use the em dash, why did he enshrine it in nature? In the horizon line—the lightning-harrowed bough—the canyon's pink striation—the pupil of the goat

why open up a gui when you can just look at these unicode curves

thinking about Him (bilbo baggins on this edition of the hobbit)

why I read writers’ diaries

infrastructure that looks like sci fi 1/ liquid natural gas tanker

Once we added terrain editing to Tiny Glade, we had an important game design question: how would sheep handle it? Well, these cuddly little floofs are not mountain goats, so we gave them tiny umbrellas 🐑🌂

imagining what a text editor optimized for non-native speakers could look like

I need to know who at @United is responsible for this security question and drop-down list of options (!!!)

so stinkin' proud of @jgaeb1, whose paper on causal fairness just won an ~outstanding paper award~ at #ICML2022 !!! 🏆 paper: arxiv.org/abs/2207.05302 blog: jgaeb.com/2022/07/18/pre…