Giuseppe Zangari
5.5K posts
Giuseppe Zangari
@zangariPower
Innovation & strategy. Executive MBA. Many projects. One pattern: curiosity → experiment → understand.
Lombardia, Italia Katılım Eylül 2010
1.2K Takip Edilen388 Takipçiler
When AI agents will enter their accountability era? 😂💶
“Sorry for the misdirection.”
Meanwhile your token balance: 📉
#ClaudeCode #AgenticAI #BuildInPublic #GenAI
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Gallup simulates opinions with AI. Not replacement. Depth. The real innovation? Knowing what to ask next. #AI
news.gallup.com/opinion/method…
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Giuseppe Zangari retweetledi
🚨 The world’s first open-source 100B medical LLM is here 🏥 Local inferencers have a Health model option to run at home.
AntAngelMed (100B params, only 6.1B active) recently released:
✅ Tops open-source models on MedBench & HealthBench
✅ 200+ tokens/sec on H20 hardware
✅ 128K context length
💪 Strong in medical reasoning, safety & empathy
🔒 Runs locally (full privacy)
⚡ Only 6.1B active params (very efficient)
🧠 Fine-tunable for hospitals & research
🖥️Practical Deployment Options for AntAngelMed (100B Medical LLM) (all are only estimates)
✅ Best Balance → INT4 (~50 GB) on 2–4x GPUs (RTX 5090 / 4090)
✅ Max Quality → FP8 (~100 GB) on (DGX Spark, Mac Studio 128GB)
✅ Budget Option → INT4 (~50 GB) on 2x RTX 4090 + CPU offload (slower)
❌ Single RTX 5090 (32GB) → Not recommended (model too big)
❔ GGUF could bring down the size even more
Built by Zhejiang Health + Ant Healthcare.
A big jump for open & privacy-friendly medical AI.
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@antirez It’s very LLM dependent, I think learning to prompt to specific models is a skill that must be developed. BTW I’ve tried your letter.md techniques, it works! I use it also help in context reconstruction.
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What happens when I use autocoding is *very* strange, is something that didn't exist in myself, in the past. I write big chunks of text to the LLM and every word I type I "feel" how it is going to condition the work of the agent in one way or the other. Every word reduces the error.
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@Context_Mike @AlexFinn Use case: escape permanent underclass I guess
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@AlexFinn Why do I need Hermes + OpenClaw? Im curios, as I’m happy with my custom OpenClaw setup on my Mac mini. Wouldnt it be an issue to add hermes? What’s the usecase ä?
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Every AI tool you need to escape the permanent underclass:
• Codex app (5.5 medium on fast mode)
• Hermes Agent (powered by local model)
• OpenClaw (ChatGPT 5.5 oauth)
• Gemma 4 running on a Mac Mini
• ChatGPT 5.5 Pro for planning
• Claude Design for front end design
• Claude Code for front end development
• ChatGPT Image gen 2 for more than you can imagine
• Spotify playing lofi bangers
• 2nd monitor that has these agents up 24/7
Do work on 1st monitor. Constantly prompt 2nd monitor
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Update on Opencode Go
It’s great value for $5/month, there’s really no reason not to do the first month.
At $10/month it’s still good value and gets you access to all sota OS models. You can’t daily drive it without hitting limits on the big models but w/ Kimi x3 you won’t hit limits unless you’re insane.
Overall highly recommend the first month, then make your own decision.
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@LottoLabs @Joash0x Yes, an I think it become slower after some hours. But it’s ok and I am loving it at the moment.
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@neilquinn @agupta you can test it with past market data, like predicting last month
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@agupta Super cool. I've been experimenting with Opus to look at put buying a la Taleb for the barbell strategy but haven't pulled the trigger yet. Hard for me to evaluate if it's reasonable or not.
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soooooo how are we feeling about those quant jobs everyone?
Kamryn Ohly@KamrynOhly
Our team is stunned. We gave Claude Opus 4.6 by @AnthropicAI $10k to trade on @Polymarket. It’s now has an account value of $70,614.59. This is a new era of model performance in trading and predicting outcomes in the face of uncertainty. @predictionbench
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Totally agree, GitHub profile is becoming very important also for executives and managers. #AI #coding
Garry Tan@garrytan
I came back to code because AI made it possible for me to build at a level I couldn't before. I'm not coding despite being CEO of YC. I'm coding because this is the most important technological shift since the internet and I'd be an idiot to experience it from the bleachers. I'm 45, running the most important startup institution in the world, and I can ship production software at 2am. That's not a distraction from the job. That is the job understood correctly.
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“It is urgent to live enchanted.”
— Valter hugo mãe
via the 5-Bullet Friday newsletter (tim.blog/fbf) from @tferriss
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@TheItalianExit the place is fantastic, but challenging location because yo do not have many infrastructures around mhf.zangari.me/?q=Casole%20d%…
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What €150K buys in Casole d'Elsa: 130sqm across 6 rooms, 1 baths. Try finding that in any Western capital. Italy's 7% southern retiree flat tax and €100K/year non-dom regime make relocation a spreadsheet exercise.
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About Casole d'Elsa: it's in Tuscany, the region that invented the Renaissance. Rolling hills, vineyards, cypress-lined roads. Nearest airport: Firenze (FLR) at 59km. Zero coastal exposure, which keeps prices honest and tourism local.
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@diehardmetsnj @sentdefender Signals must be sent otherwise everything seems allowed, from bombing civilians to threatening entire civilization. There are other ways.
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@sentdefender She will change her mind when Russia comes knocking.
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According to Italian Prime Minister Giorgia Meloni, her government will not renew a defense agreement the country has with Israel that comprised of technological cooperation and military equipment exchanges, citing the situation in the Middle East for the move.
Full Comment:
In view of the current situation, the government has decided to suspend the automatic renewal of the defense agreement with Israel.
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@CarloCalenda Tra l’altro col titolo che va bene in borsa
Italiano
Assurdo rimuovere così Cingolani senza spiegazioni in un settore delicato dove era apprezzato dagli investitori e dai partners. Ed è necessario che il Governo chiarisca se ci sono ragioni di sicurezza o di performance. Eventuali ragioni di appartenenza politica confermerebbero un andazzo del Governo che decisamente non sta portando bene.
Marco Lombardo@mlombardo81
Poche settimane fa il CEO di Leonardo, l’ex Ministro Cingolani, aveva annunciato il lancio di un sistema di difesa aerea multistrato, noto come «Michelangelo Dome» con un piano strategico quinquennale e investimenti in intelligenza artificiale e cybersicurezza. Un piano presentato nel silenzio assordante del dibattito politico. Ora circola l’idea di un cambio al vertice di Leonardo dentro il “risiko delle nomine" che riguarda il rinnovo dei vertici di 155 società partecipate pubbliche italiane. Siamo proprio sicuri che in questo momento così delicato per il riarmo e la difesa europea lo spoil system del governo sia la mossa giusta? Si può sapere con quali idee e con quali criteri il Governo Meloni intende affrontare il capitolo delle nomine?
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OpenOats v1.12.0 is out -- massive update for the open-source meeting copilot.
New: your Mac now auto-detects when you join a Zoom, Teams, or FaceTime call and asks if you want to transcribe. Just tap the notification to start. No setup, no remembering to hit record.
Also shipped:
- File permissions hardened to 0600 + Spotlight indexing blocked on all transcripts
- Pluggable transcription backend protocol (adding new ASR models is now a one-file change)
- 133 unit tests across core modules
All local, all private, all on-device.
github.com/yazinsai/OpenO…
yazin@yazins
Just shipped the biggest update to OpenOats (prev OpenGranola: the open-source meeting copilot for macOS): Meeting Templates + AI Notes ✨ Pick a template before your meeting (1:1, Customer Discovery, Hiring, Stand-Up, Weekly) and after it ends, generate structured notes from the full transcript with one click. Notes stream in real-time as the LLM writes them. Browse past sessions, regenerate with different templates, copy to clipboard. Also fixed a subtle bug where the last ~3 seconds of audio could be lost when stopping a session. Now the app gracefully drains all buffered speech before closing. 4 new files, 1,277 lines added. All open source. github.com/yazinsai/OpenO…
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Weak signals become visible. Built an OSINT dashboard mapping geopolitics, markets, and media in real time. Explore it: myosint.zangari.me #OSINT #Geopolitics #IranWar
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@homegymcoop What can be a good set with decent resistance for travelling? Or to add variety to garage gyms?
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Resistance bands remain, to this day, the most underrated fitness product ever created.
They take up no space. Cost next to nothing. And can do millions of exercises with incredibly high levels of resistance.
I don't travel without them.
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