Dr Mike
109 posts
“I hate cancer. But I'm also grateful for it,” says former Sen. Ben Sasse. “I tell a lot more truth to myself than I used to do it when I thought I was super omni-competent and interesting.” cbsn.ws/4d6kPFE
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@sircalebhammer Caleb dropped one sentence and activated a thousand think pieces. Props
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@APompliano What’s your base case for inflation if they did that tomorrow?
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The Fed needs to cut interest rates by about 100 basis points.
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go to bed
right now
i know the build is almost finished
the eval can wait til morning
the agent will still be failing tomorrow
you won't figure out why it's hallucinating
yes your coworker ships on 4 hrs of sleep
they also hallucinate a lot
off you go
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Living off $8,000/mo in America is probably borderline poverty level and that’s scary because there are many people out there living below that income threshold.
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@hubermanlab @AliaCrum @Stanford Curious where you think the ceiling is—% performance swing from belief alone?
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I just fired my entire medical team.
Sold my sauna and HBOT.
Cleared my shelfs of all pills.
Let my blood boy go.
Brandon Luu, MD@BrandonLuuMD
Literally just having a delusional golden retriever mindset measurably changes outcomes and physiology. Sleep badly? Convince yourself you're well rested. Stressful day? Convince yourself it's fuel. Failed? Convince yourself it's useful data.
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@bryan_johnson The oral-systemic link is real—but the leap to causation is still doing heavy lifting here. Periodontal disease likely reflects systemic inflammation more than being the driver.
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Your gums may be a back door to Alzheimer's.
> gingipain antigens (toxic bacterial enzymes) found in 91–96% of postmortem Alzheimer's brains
> bacterial DNA detected in the spinal fluid of 7 out of 10 living Alzheimer's patients
> in mice: oral infection increased brain tau tangles by roughly 500% and amyloid plaques by 140%
> in 3,251 humans: 22% higher Alzheimer's risk per SD increase in gum pathogen antibodies (up to 26 year follow up)
> clinical data: a protease inhibitor slowed cognitive decline by 57% in patients with active infection
Your dentist may be your most underrated Alzheimer's doctor.
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@60Minutes This isn’t a loss, it’s a shift. Lifetime careers were the exception, not the rule historically. We’re just back to a skills-based economy—faster and less forgiving.
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“We’ve never lived in a world where 22-year-olds couldn’t assume that the work they did they would be able to do until death or retirement, and we’re never going to have that world again,” says former Nebraska Sen. Ben Sasse.
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@whiskyhenderson @davidasinclair Not a dumb question at all — most adults don’t know. Clinically, we usually assume prior exposure and proceed with shingles vaccination without testing.
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@davidasinclair What if you don’t know if you’ve had chicken pox? I’m sure this is a dumb question, but asking nonetheless.
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Done. Herpes virus neutralized 🦠
Not taking any chances with my longevity, now that shingles is associated with faster aging (though not yet a known cause). If you’re 50+, consider it. The shot will likely be money- & pain-free
I even got a $5 voucher for being a brave boy💪
David Sinclair@davidasinclair
Will be getting a shingles shot ASAP
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@davidasinclair Practically speaking, assume prior exposure in adults. Shingrix without testing is already the default in many cases.
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Ask your doctor for a Chicken Pox VZV test. If you're positive, the shingles vaccine is the next step. If you've never been exposed, you can get a chickenpox vaccine, which is safe for adults, too
Whiskey Henderson@whiskyhenderson
@davidasinclair What if you don’t know if you’ve had chicken pox? I’m sure this is a dumb question, but asking nonetheless.
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Elon Musk has used SpaceX as a kind of piggy bank over the last two decades, turning to the company as a financial tool to get loans and bolster his struggling companies, according to an examination by The New York Times. nyti.ms/4w8dInZ
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I’ve invested in 700 private companies
Providing liquidity and loans to high performing founders is completely standard.
In fact, investors encourage loans and secondary sales for founders to enable them to go for the Gold — which is exactly what SpaceX has done.
The @NYTimesPR is presenting this as a controversy, when in fact it’s the private company playbook in 2026.
Another hit job from the NYT
The New York Times@nytimes
Elon Musk has used SpaceX as a kind of piggy bank over the last two decades, turning to the company as a financial tool to get loans and bolster his struggling companies, according to an examination by The New York Times. nyti.ms/4w8dInZ
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@davidasinclair Good move. Just to clarify—this is reactivation of VZV, not a new herpes infection. And the evidence linking shingles to ‘accelerated aging’ is associative, not causal. Still, preventing post-herpetic neuralgia alone makes it worth it.
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@APompliano As a doctor, calling it ‘dependency’ is a bit loaded. We don’t say that about statins or antihypertensives. If GLP-1s reduce CV risk and mortality, lifelong use is just chronic disease management.
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GLP-1s have taken the world by storm.
They started as simple weight loss drugs, but they are now evolving into lifetime prescriptions. It is estimated demand will at least double over the next 5 years.
This chronic dependency will drastically expand the types of companies who benefit from the trend.
Everyone knows about Novo Nordisk and Eli Lilly, but there are other companies in drug development, manufacturing, and packaging verticals.
READ THE REPORT: procapinsights.com/app/articles/s…
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@JakePearson303 As a physician—berberine isn’t ‘ignored because no profit.’ It’s just not as well-studied, standardized, or regulated as people think.
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There's a reason your doctor never mentioned Berberine. It can't be patented, so there's no profit in it.
For 3,500 years, this natural compound has been torching fat and optimizing hormones.
They buried it. I'm bringing it back. Here's the truth:
1… twitter.com/i/web/status/1…
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Yeah and I’m also seeing a lot more longtime Tesla bulls talk about selling after holding for 10 years. It’ll be under 300 by end of year
Gab@GabGrowth
The greatest risk for $TSLA stock is SpaceX’s IPO. For years, $TSLA was the only liquid public way to bet on Elon. A SpaceX IPO changes that.
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@Codie_Sanchez Getting sued/cheated is almost a rite of passage. The difference is whether you built in margin, leverage, and documentation beforehand.
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Billionaire: “you want to be in business?”
“Prepare to get sued and cheated. It’s eventual and also… doesn’t really matter.”
Great lesson.
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@sircalebhammer People always blame ‘the internet’ but rarely ask why the message resonates in the first place.
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This will happen for every administration going forward, left and right, because of the disgusting amount of extremism and evil echo chambers online.
These extremist in their echo Chambers literally think they are the good guys at all times- no matter what.
They will kill more.
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By the way, this will never stop. This is the literal same rhetoric that is said on live streams, podcast, and an online post every single day.
To act surprised that a person may be radicalized by it is disingenuous.
Well, maybe it is surprising that it’s only been 3 so far…
BNO News@BNONews
NEW: Cole Allen wrote a manifesto saying he was targeting Trump officials: "I am no longer willing to permit a pedophile, rapist, and traitor to coat my hands with his crimes."
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