@raouljdegroot Helemaal mee eens, dit kan ik uit eigen ervaring bevestigen!
Nederlands
Joep Beumer
298 posts
Joep Beumer
@BeumerJoep
Roche Institute for Human Biology. @IHB_Research
Basel เข้าร่วม Haziran 2018
1K กำลังติดตาม1.6K ผู้ติดตาม
Een student op de UMCU klachten/suggesties/complimenten website. Een hartverwarmende geste, die de dag een zilveren randje geeft.
Nederlands
Great opportunity to join a fantastic lab at @IHB_Research !
Gray Camp@GrayCampLab
We are searching for computational PhDs and Postdocs to join our group in collaboration with @TreutleinLab . We have exciting single-cell technology projects that incorporate bioengineering, computation, biology, translation. Send CV to deco_ihb@roche.com
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@SItzkovitz @SciReports @KerenBaHa @Oran_Yakubovsky @ilan_kent @sheba_medical @WeizmannScience Congratulations @SItzkovitz & @KerenBaHa ! Very exciting and useful approaches.
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Happy to share our new paper in @SciReports: Stool shed cell transcriptomics mirrors tumor biology and enables colorectal cancer diagnosis nature.com/articles/s4159…
Great work by @KerenBaHa, @Oran_Yakubovsky, @ilan_kent, @sheba_medical, @WeizmannScience
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@Jain_Akanksha_ @UZH_en Congrats and all the best Akanksha! Looking forward to the science from your team.
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Thrilled to share 🎉 I’m joining @UZH_en DMLS as Assistant Professor (tenure track)! I’ll launch the Neural MorphoGenomics & Developmental Dynamics Lab, exploring how genes + morphogenesis shape brain development using organoids, imaging & spatial genomics 🧠🔬🧬
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Joep Beumer รีทวีตแล้ว
Thank you everyone for the congratulations and the large number of applications! I want to specifically encourage applications for these positions:
* Postdoc in structural biology (cryoEM, ideally with X-ray too)
* Full time lab manager/technician with wetlab experience
Martin Pacesa@MartinPacesa
I am super excited to announce that I will be starting my lab at the Department of Pharmacology of the University of Zurich in Switzerland next year!
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Joep Beumer รีทวีตแล้ว
Diet/microbes place the gut epithelium as a nexus for evolutionary change. With @TheSpenceLab @genomeCraig, we use #organoids to explore how evolution prepared the developing human intestine for exposure to the environment. @ScienceMagazine #evodevo 🧵1/11 science.org/doi/10.1126/sc…
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Joep Beumer รีทวีตแล้ว
Thrilled to see #SAVANA out in @naturemethods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇nature.com/articles/s4159…
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Joep Beumer รีทวีตแล้ว
Modular integration of epithelial, microbial, and immune components to study human intestinal biology. Amazing team project with @_RubenL_, Marius Harter, @CY_Qianhui_YU, @mike_nikolaev, @TheLutolfLab, Nikolche Gjorevski, and many others @IHB_Research biorxiv.org/content/10.110…
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Joep Beumer รีทวีตแล้ว
New insights into the actions of GIP agonism vs. antagonism on food intake and body weight in mice from Timo Muller and colleagues #weightloss #obesity @NatMetabolism @TimoMueller_IDO @MatthiasTschop
nature.com/articles/s4225…
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We are searching for 2 talented MSc students to join the group! If you are interested in using advanced organoid models to study regulators of intestinal differentiation or nutrient uptake, please apply! go.roche.com/skt2b and go.roche.com/wf7hj
@IHB_Research
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Joep Beumer รีทวีตแล้ว
A new peptide, BRINP2-related peptide (BRP) administered pharmacologically, reduces food intake and exhibits anti-obesity effects in mice and pigs without inducing nausea or aversion.
nature.com/articles/s4158…
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Great pleasure to host @SItzkovitz at @IHB_Research. Exciting talk & discussions on spatial transcriptomics of adult tissues. Including promising translational applications of using shed intestinal cells for longitudinal profiling of homeostatic and diseased cell states!
Institute of Human Biology@IHB_Research
A big thanks to @SItzkovitz of @WeizmannScience visiting #TeamIHB! We were fascinated to learn how spatial and shed cell transcriptomics of the human digestive tract can illuminate how single cells in mammalian tissues collectively achieve physiological goals.
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Joep Beumer รีทวีตแล้ว
Joep Beumer รีทวีตแล้ว
Our first 2025 paper!
We discuss in @NatRevMCB how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @almagro_jorge
nature.com/articles/s4158…
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Joep Beumer รีทวีตแล้ว
iFlpMosaics are now published @naturemethods. A compendium of novel genetic tools and related methods for inducing and analysing genetic mosaics in a high-throughput manner. nature.com/articles/s4159… Tweetorial 👇
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Joep Beumer รีทวีตแล้ว
We updated our BindCraft preprint with lots of new exciting results! We release all our binder sequences and models, include more in silico analysis, novel design targets, and present AAV retargeting to specific cell types using de novo binders!
biorxiv.org/content/10.110…
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Joep Beumer รีทวีตแล้ว
Joep Beumer รีทวีตแล้ว
📢We are hiring a postdoctoral researcher 📢
Are your curious about the mechanisms driving metastatic spread? Do you have *bioinformatics* skills to help us unravel these mechanisms?
We (@Bergerslab, @ColindaScheele) may have your dream job @VIB_CCB!
jobso.id/k7cp
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Only 2 weeks left to apply for our junior & senior group leader calls! Join us in Basel to do cutting edge basic and translational research on human disease. In a very collaborative environment, where you can leverage state-of-the-art human model systems and technology platforms.
Institute of Human Biology@IHB_Research
📢Open call for Scientific Group Leads! #TeamIHB seeks stellar Junior & Senior scientists to start research groups on innovative and translational #HumanModelSystems. Expertise in #Immunology, #Neurology, #Ophthalmology, #Metabolism or #Oncology a➕! More go.roche.com/11jc8
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Joep Beumer รีทวีตแล้ว
The GLP-1 drugs we've got now are just the beginning. The gut nutrient cell sensors ( a cellular instead of a peptide hormone target) have considerable potential.
Brief thread by @HansClevers on their new @ScienceMagazine paper
Hans Clevers@HansClevers
New @ScienceMagazine study in collab with @IHB_Research! We identified novel receptors on enteroendocrine cells (EECs) that regulate secretion of endogenous hormones. These harbor therapeutic potential for metabolic disease. Read the paper go.roche.com/m9hah or 🧵⬇️
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