Rubén López Sandoval

Modular integration of epithelial, microbial, and immune components to study human intestinal biology. Amazing team project with @_RubenL_, Marius Harter, @CY_Qianhui_YU, @mike_nikolaev, @TheLutolfLab, Nikolche Gjorevski, and many others @IHB_Research biorxiv.org/content/10.110…

Please join us in shaping the future of human biology research and help to translate it into real-world applications in pharmaceutical research and development!

✨#TeamIHB's success owes much to our wonderful and inspiring people. Today meet Mar, R&D engineer in the #Microtechnologies group. More about her at go.roche.com/ea0mk & stay tuned for more Faces of Innovation stories celebrating the amazing people driving our innovation!✨

Imagine growing a miniature version of the human intestine in the lab to study gut biology in great detail and test medicines before clinical trials? We are happy to share our latest publication on bioengineered human mini-intestines: authors.elsevier.com/sd/article/S19… Let’s dive in!

🌟 NEW PAPER ALERT: Breakthrough liquid biopsy publication in @CellCellPress🌟 Excited to share that our liquid biopsy tech is featured in iScience! 🎉 Our paper, "An electro-optical platform for ultrasensitive detection of small extracellular vesicle sub-types," showcases our Nano-Extracellular Omics Sensing (NEXOS) technology. Read more: cell.com/iscience/fullt…

Join our team and contribute to the development of engineered models of intestinal inflammation to study #IBD and derive novel therapeutic approaches. This is a unique postdoc position hosted by the Immunology department within Roche pRED, in collaboration with the @IHB_Research Apply here: lnkd.in/dx7i9Zsr

Dr. Nikolche Gjorevski and colleagues at @Roche show that patient-derived intestinal organoids and tumoroids supplemented with immune cells can be used to study the on-target off-tumor #toxicities of T cell-engaging bispecific antibodies. go.nature.com/3vrxCiL

1. Adult stem cells (ASCs) compensate for cell loss during daily wear and tear. Evolution has created a variety of stem cell designs. In this review, @HansClevers and I define six hallmarks that are key enabling features of the basic function of ASCs, replacing lost tissue.

El @IHB_Research @Roche lidera la investigación farmacéutica con organoides 👨‍🔬 Su enfoque busca fármacos más efectivos y la automatización del cultivo de organoides. Lo cuenta en esta entrevista de @pilar_pj en @elmundoes el investigador García Cordero👇elmundo.es/ciencia-y-salu…

#TeamIHB's inaugural IHB Science Days 2023 brought together our #HumanModelSystem scientists for 2 days of deep dive talks, science slams, workshops and fun! Congrats to our presentation winners @NinoukAkkerman @Giuliana_Rossi_ @_RubenL_ @CamachoRufino, Adrian, Marius & Lukas!

We developed a method for spatiotemporal transcriptome measurements during bacterial swarm development, which revealed cross-feeding across generations! Now out: 👇 nature.com/articles/s4156…

Human intestinal organoids with autologous tissue-resident immune cells biorxiv.org/content/10.110…. Incredible how they incorporate into the epithelium! Foundational tool for basic and translational research. Inspiring collab with Nikolche Gjorevski and @IHB_Research! #organoids

Proud to lead this project with @josch_f Leander Dony. Great collaboration of @TreutleinLab @GrayCampLab @fabian_theis! We generated the first neural organoid cell atlas and compared it to the primary. Twittorial will follow later

Exciting times at @IHB_Research! A new PhD program with @ETH_BSSE -> next-gen-bioengineers.ethz.ch/doctorate.html. A search for new group leaders (early career) -> institutehumanbiology.com/about-the-ihb/…. It is a very interesting intersection at the moment: Exploration, Engineering, Translation! #Organoids #Basel

Very excited to share that we have just launched a joint doctoral programme for Translational Engineering of Biological Systems together with @ETH_BSSE next-gen-bioengineers.ethz.ch/doctorate.html

We’re proud to introduce you to #TeamIHB, a group of highly talented and curious scientists! 📣 We’ll be taking you through each IHB department in turn, starting this week with the Developmental Systems and Computational Biology ⬇️

We have a big announcement! You may have heard of the ITB (Institute for Translational Bioengineering) and our exciting research into #Organoids. Well, the ITB is now the IHB (Institute of Human Biology)—and our research has suddenly got a lot more exciting 🧵⬇️

We are very excited to welcome you in Basel soon. We are delighted to share that's its a full house! thank you for all the enthusiasm 🥳 #BaCell3D 2023 #KHAUS🇨🇭! Countdown begins, picture shows the promising view of the Rhein and your organisers hard at work!

Save the date! "Multicellular systems in 3D" conference soon to happen in Basel. Super exciting!

Save the date! Single Cell Genomics 2023 #SCG2023 takes place Oct. 9-11 2023 in the beautiful mountain town Engelberg in Switzerland! 10th year anniversary of this unique experience. @IdoAmitLab, @slinnarsson, @AlexandervanOu1, @MarioniLab, @sandberglab, Aviv Regev, Amos Tanay