Pietro Genovese

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Pietro Genovese

Pietro Genovese

@Genovese_Lab

Faculty at Dana Farber / Boston Children’s @DFBC_PedCare. Advanced genetic engineering of hematopoiesis Lab.

Boston, MA เข้าร่วม Nisan 2019
274 กำลังติดตาม423 ผู้ติดตาม
Pietro Genovese
Pietro Genovese@Genovese_Lab·
Thrilled to see the great work from @danielevanbauer lab featured in @NatureBiotech! The discovery that a limited nucleotide pool in HSPCs constrains prime editing is a leap forward in gene editing technology. A huge shoutout to @SbastienLevesq4 and the entire team!
Sébastien Levesque@SbastienLevesq4

My postdoc work in the @danielevanbauer lab is out @NatureBiotech! We found that the limited nucleotide pool in hematopoietic stem and progenitor cells (HSPCs) constrains reverse transcription and thus prime editing (PE). nature.com/articles/s4158…

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Adam Thiesen
Adam Thiesen@adam_thiesen·
I think I will start posting all my videos on X primarily. I hope you all put in more tools for video editing @elonmusk Here is a video about a recent Nature paper where base editing is used to protect myeloid cells during cancer treatment nature.com/articles/s4158…
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Genetic Engineering & Biotechnology News
Genetic Engineering & Biotechnology News@GENbio·
Base Editing Tweaks HSC Epitopes for Targeted Immunotherapy Base editing of HSPC epitopes makes targeting genes key to leukemia survival possible, even if those genes are also expressed on HSPCs. Learn more: ow.ly/j9TF50PGbIc
Genetic Engineering & Biotechnology News tweet media
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Pietro Genovese
Pietro Genovese@Genovese_Lab·
@davidrliu @Nature Thank David. Glad you enjoyed our work, and thanks very much for having developed such powerful precision gene editing tools.
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David R. Liu
David R. Liu@davidrliu·
Casirati, Genovese et al. report in @Nature that base editing of epitopes in hematopoietic stem cells equips blood cells with the ability to evade CAR-T cells or antibodies, allowing the use of anti-leukemia drugs targeting epitopes that kill cancer cells, but previously could not be used because they would also kill healthy blood cells. Another elegant application of precision gene editing to enable otherwise impractical or unsafe therapeutic strategies. nature.com/articles/s4158…
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Pietro Genovese
Pietro Genovese@Genovese_Lab·
Excited to share our latest publication about epitope editing in hematopoietic stem cells to enable targeted immunotherapy for acute myeloid leukemia. Congrats to @CasiratiG and all collaborators for this amazing work. nature.com/articles/s4158…
Gabriele Casirati@CasiratiG

I'm thrilled to announce that our work, 'Epitope Editing Enables Targeted Immunotherapy of Acute Myeloid Leukemia,' is out today in Nature journal! Link: nature.com/articles/s4158… doi: doi.org/10.1038/s41586…

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Eleonora Dondossola,PhD
Eleonora Dondossola,PhD@ED_PhD_·
This time, our Employee Appreciation Month gift included a beach bag. I had to use it wisely! GU Medical Oncology, keep branding the world
Eleonora Dondossola,PhD tweet media
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Pietro Genovese รีทวีตแล้ว
BioCentury
BioCentury@BioCentury·
Gene editing stem cell transplants makes myeloid and T cell therapies safer, according to data at #ASH22 buff.ly/3hCEDqz
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Pietro Genovese รีทวีตแล้ว
ASGCT
ASGCT@ASGCTherapy·
With #geneediting, researchers restored levels of CTLA-4 in T cells from patients with CTLA-4 insufficiency. In mice, they improved symptoms. ASGCT members involved: @RealDrfox, MbChB, PhD; Claire Booth, MBBS, PhD; Pietro Genovese @Genovese_Lab, PhD: ucl.ac.uk/news/2022/oct/….
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Paula Río
Paula Río@PauFerrol·
We had a dream….and it is a bit closer…Correct a mutation where it is happening,…still many steps to move it to patients but this is the first step!!!!Really greatful for an amazing collaboration with ⁦@jcornlab granted by ⁦@EJPRareDiseases⁩ nature.com/articles/s4146…
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Ben Kleinstiver
Ben Kleinstiver@BKleinstiver·
Very humbled (and lucky!) to receive an @NIH_CommonFund @NIHDirector DP2 award. 🥉time was the charm. Grateful for this recognition that will allow my amazing lab members to continue pursuing their super interesting science. #CRISPR @CGM_MGH @MGHPathology @MassGeneralNews
Ben Kleinstiver tweet media
NIH Common Fund@NIH_CommonFund

Early-stage investigators proposed innovative high-impact research ideas for the @NIHDirector’s New Innovator Award. See the projects the awardees will pursue: bit.ly/hrhr2022nia #NIHHighRisk

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Valentina Vavassori
Valentina Vavassori@ValentinaVavas2·
These are exciting but hard times for #genetherapy . It’s heartbreaking to witness withdrawal of effective gene therapies from the market. They are often the only cure for many rare conditions, saving lives of other human beings. Don’t miss this!
Nature Medicine@NatureMedicine

Ensuring a future for gene therapy for rare diseases. Comment from Alessandro Aiuti @francescapasi and @NaldiniLab San Raffaele Telethon Institute of Gene Therapy, Italy nature.com/articles/s4159…

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Alberto Angela
Alberto Angela@albertoangela·
Buon viaggio papà.
Alberto Angela tweet media
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ค้นพบ

@danielevanbauer @NatureBiotech @SbastienLevesq4 @ferrari_sam93 @adam_thiesen @andrea_csn @elonmusk @GENbio