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@StrengthDebates Guide

Comment “Guide” I’ll send a 25% discount code to my 89 page Low Rep Hypertrophy Set Guide. You need to check 3 boxes. 1. High Effort 2. Time of Tension 3. Accumulated Volume What is a hypertrophy set?? If all reps check 1 and 2 then it’s a hypertrophy set. Accumulate 18-36 total reps, do that every session on 1-2 of your compound exercises Replace junk volume with meaningful reps, and oh by the way you will become much stronger and faster training this way. You don’t get as strong using a traditional 8-12 rep approach and I would argue you can’t get as big either. This method is especially helpful for Natty lifters. More stimulus at a volume that drives myofibril hypertrophy

@BigT_Broncos I took it out of the box, weighed myself, got a way too low reading, and instantly returned.

I had my first Dexa scan today. I purchased a Hume scale last year and they make some pretty strong claims about their accuracy so I was curious to see the difference. The scale had my body fat this morning around 11.7%, which I knew was pretty far off. I guessed I was around 20%. Dexa came out at 18.1%. The scale is a cool tool, tracking a lot of different metrics, but as far as accuracy goes, it’s no surprise it pales in comparison to Dexa.

@brentlajeunesse We are 90% aligned.

Good morning, warriors! 🌅 Happy Friday! New morning protocol locked in and firing on all cylinders: • 400mg Test C per week • 3mg HCG m/w/f • 5mg Reta/week • 2iu GH daily • 3 mg KLOW daily • Selank/Semax/Dihexa (nasal spray) • 20mg tadalafil/daily • 20mg methylene blue/daily Haters gonna hate. They’ll call me a cheat, a druggie, whatever. I’m just out here optimizing, recovering, and pushing limits. Let’s fucking go! 💪

@JayCampbell333 CHEATSHEET

55 years old. Single-digit body fat. Year-round. 25+ years of self-experimentation. RETATRUTIDE, BPC-157, RECOMBINANT FOLLISTATIN, and more. This is my exact optimization stack. Every compound, every dose, and why it made the cut: 1. TESTOSTERONE TESTOSTERONE is the foundation. • I take 60mg of TESTOSTERONE CYPIONATE three times a week. Monday, Wednesday, Friday. No exceptions. • Muscle, mood, libido, body composition. It drives all of it. • Every peptide I use sits on top of this base. Without it, nothing else works right. 2. RETATRUTIDE RETATRUTIDE is the most powerful fat loss compound available right now. Most weight loss drugs target one receptor. This one targets three: • GLP-1 for appetite suppression. • GIP for fat clearance. • GLUCAGON for metabolic rate. No other compound hits all three. I take 0.20mg 2-3x per week. In Phase 1 trials, RETATRUTIDE led to 8.96 kg of weight loss in 12 weeks. • TIRZEPATIDE took 40 weeks to hit similar numbers. And the majority of weight lost was pure fat, not muscle. That's why it's my top pick for body composition. 3. SS-31 SS-31 is the compound nobody talks about that makes everything else work harder. • It targets the inner mitochondrial membrane and binds to cardiolipin. • It prevents oxidative damage and boosts ATP production. • One biochemist told me it's the ATP equivalent of 6 months of endurance training in a single injection. • I take 300mcg every morning. I've been hearing that higher doses (5-15mg daily) are even more effective. 4. BPC-157 + TB-500 For recovery, I use BPC-157 and TB-500. I call it the Wolverine Stack. • BPC-157 heals by forming new blood vessels. • TB-500 repairs tissue by building actin protein. • Together they accelerate healing beyond what either does alone. • If you train hard and you're over 30, you need both of these stocked at home. 5. TESAMORELIN + IPAMORELIN TESAMORELIN and IPAMORELIN are my go-to growth hormone peptides. • TESAMORELIN is a GHRH that mimics 1-2 IU's of HGH. I take 1-2mg every night before bed. Best for men to burn through belly fat. • IPAMORELIN amplifies natural GH pulses and counteracts somatostatin. Best for women. Together they're synergistic. 6. MELANOTAN 1 Most people think MELANOTAN 1 is just for tanning. • It's actually a synthetic analog of alpha-MSH that enhances DNA repair, reduces inflammation, and boosts your body's antioxidant defenses. • I take 0.25mg daily for skin protection and consciousness enhancement. This one is seriously underrated. 7. THYMOSIN ALPHA-1 THYMOSIN ALPHA-1 is my immune system backbone. • It strengthens your body's first line of defense by boosting key immune signaling. • Research shows it enhances anti-tumor immunity with minimal toxicity. • In a world full of immune stressors, this is non-negotiable. 8. RECOMBINANT FOLLISTATIN At 55, I'm the biggest and leanest I've ever been. • Inconsistent training. • Travel chaos and suboptimal sleep. • Still gained measurable muscle while getting leaner. The reason? RECOMBINANT FOLLISTATIN. It inhibits myostatin. The protein your body produces to stop muscle growth. Old follistatin failed. It broke down in 1-2 hours and caused dangerous off-target effects. RECOMBINANT FOLLISTATIN only targets myostatin. • It increases muscle mass AND strength. • Prevents muscle loss during caloric deficit. • If you're on a GLP-1 and worried about going skinny-fat, this is the answer. Why this many compounds? Because the healthcare system is designed to manage your decline. I'm not managing decline. I'm engineering peak performance at 55. That's what fully optimized living means. I put together a free Peptide Cheat Sheet breaking down every compound and protocol you MUST know. Comment ’CHEATSHEET’ for the direct link in your DMs. I will DM you

@bryan_johnson Love that you’re asking these questions and explaining publically. Here for this.

Just spent over an hour with my clinical team debating which growth hormone peptide protocol to run. Still torn. Wanted to share the thinking and get your take. The goal: Increase GH and IGF-1 to support anabolism, recovery, and sleep, but also test a specific stacking hypothesis. Tirzepatide (GLP-1/GIP agonist) can elevate resting heart rate, disrupt sleep, and suppress appetite aggressively. CJC-1295 (GHRH analog) can worsen insulin resistance. The bet is that combining them cancels each other's downsides: CJC-1295's slow-wave sleep enhancement offsets tirzepatide's sleep disruption, while tirzepatide's insulin-sensitizing effects counteract CJC-1295's insulin resistance. Best of both worlds — or at least, that's the hypothesis we're testing. The two candidates: CJC-1295 with DAC: the long acting version. One injection per week, stays active for 6–8 days. This is what was used in the actual clinical trials. Raises GH 2–10x and IGF-1 1.5–3x from a single dose. Preserves GH pulsatility even under continuous stimulation. The tradeoff: if you get side effects, you're committed for a week. Harder to titrate. CJC-1295 without DAC + ipamorelin: the short-acting version paired with a selective ghrelin receptor agonist. Daily injections, pre-bed, clears in 30 minutes. Ipamorelin adds a second axis of GH release, pulse frequency via the ghrelin pathway, on top of the amplitude boost from CJC. No cortisol or prolactin elevation. This is what most clinicians prescribe and most of the peptide community uses. The tradeoff: less clinical trial data, daily injections, more anecdotal evidence base. What we're considering: Start with DAC at half dose 2.4 mg, then if well tolerated escalate 4.8 mg, weekly injection. If side effects aren't tolerable, switch to no-DAC + ipamorelin (100 mcg then 200-300 mcg daily, before bedtime). Or, Run both head to head. 2 weeks DAC, 2 weeks no-DAC + ipamorelin and compare. Tracking: GH, IGF-1, Cortisol, CGM, real time core body temperature, RHR, overnight HRV (rMSSD), IGF-1, HOMA-IR, sleep architecture, subjective recovery. The purist in us says stick with DAC; that's where the published data lives. Yet the pragmatist says no-DAC + ipamorelin is what thousands of people actually use, and testing it generates more socially relevant data.

@peptidemaxxer Here for this, man. Love the disruption vibe.

my goal is to make vril labs free for everyone. team is against it, huge costs stacking up but asking family&friends for money for thorough testing doesn’t feel right to me hope you appreciate that. we’re all in this together. thank you for your trust! vril⚡️

@SecKennedy @bengreenfield Wait. Also deliver the PRICES!

Today, we took long-overdue action to restore science, accountability, and the rule of law. In September 2023, the Biden FDA pushed a number of peptides into Category 2 — “Bulk Drug Substances that Raise Significant Safety Risks” — driving a dangerous black market that puts Americans at risk. Now, after nominators withdrew 12 peptides, the FDA will remove them from Category 2 and will bring them to PCAC at its next two meetings, beginning in July—where independent experts will rigorously evaluate each substance on its scientific merits using full clinical, pharmacological, and safety evidence. • BPC-157 • Thymosin beta-4 fragment (LKKTETQ) • Epitalon • GHK-Cu (injectable) • MOTS-c • DSIP (Emideltide) • Dihexa Acetate • Ibutamoren Mesylate • Melanotan II • KPV • Semax (heptapeptide) • Cathelicidin LL-37 This action begins to restore regulated access and will immediately begin shifting demand away from the black market. We will follow the science, enforce the law, and deliver the clarity patients, providers, and pharmacies deserve.

@SecKennedy @bengreenfield Great stack right here.

@hanz69er I’m doing this with an OpenClaw!

Last year during prep I tracked all my drug use with an Excel spreadsheet. While it worked, it was tedious and not reusable—too much setup and too much typing. So I've been working on a better solution and I'm curious to hear what y'all think. The goal with this app is to make it easy to track drug and supplement use and to create historical reports for cross-referencing with bloodwork or any kind of biometric data. If you're interested in being a beta tester, DM me. There's an iOS app and a web app so everyone should be covered.

@ItIsMikeFitz Following for this. I love posterior chain and want to figure out pressing better.

Ok… Gave the lever arms another shot for posterior chain day and I’ve gotta say... I’m sold!! Took a minute to dial in the setup and angles, but once I did I was able to run RDLs, Bulgarians, hip thrusts, calf raises (via belt squat), and back extensions (was super easy to do a drop set) really effectively. The RDLs especially felt great. Being able to load the weight slightly behind me lit up my glutes and hamstrings way more than I expected. Kept the handles a bit forward too, which made the load feel heavier because of the leverage (duh 😆). After tonight, these are definitely staying in the rotation. Upper body is next. Going to take some time to learn the angles there and see what they can do.

@trikomes @JayCampbell333 is your man.

Who's someone worth talking to about peptides like BPC-157, who has used it themselves and understands the underlying biology as well as anyone can?

@limitlesstack @concordia_44808 Same. Think I’m a fast metabolizer. Feel very little from moda. Feel incredible on armoda.

@concordia_44808 yeah its non sense. modafinil is 50% armodafinil anyway lol. sleep issues are valid though, longer half life, really has to be taken very early, 4-6am. love armodafinil personally.

modafinil is seriously so easy to run but everyone messes it up big time the pitfalls every noob falls into: taking it too late - half life is 12-15 hours - a 10am dose = 3 hours of lost output - and guaranteed sleep problems that night solution: set a second alarm 2 hours before your real one. pop the modafinil. go back to sleep. by the time you wake up, modafinil is fully onset. wake up turned ON. sleep issues pushed back by 2 hours. skipping choline - modafinil burns through acetylcholine - no choline source leads to headache at 5pm - foggy evening - wasted second half of your day solution: 500mg citicoline in the morning. not optional. solves all of it. modafinil doesn't feel stimulatory - some people are poor responders due to CYP3A4 enzyme variation - they metabolise it too fast for plasma levels to build properly solution: switch to armodafinil. it's the purified r-enantiomer. roughly 1.5x more potent at the same dose. slower onset, longer peak. some people prefer modafinil. some armodafinil. just genetics. i love both. not drinking water - modafinil is quietly dehydrating - most of the "side effects" people complain about are just dehydration solution: 1 extra litre minimum. include electrolytes. i like to have several san pellegrino bottles on my desk. drink more if you're also on caffeine. eating too late or not at all - it kills appetite - you know this - but running it fully fasted all day then crashing into a massive meal at 8pm - destroys your sleep solution: small meal in the morning. kefir is great. eat a larger meal in the evening, but not massive. keep the brain fed. no cycling - with daily use, sleep debt compounds disproportionately by day 5-6 - by day 7 you're running modafinil on terrible sleep solution: 5 days on 2 days off. or. 3 days on 1 day off. after a few weeks. your off days feel like modafinil days anyways. making too much money: sorry, this is a natural byproduct of modafinil use, can't help with that one. solution: quit. what i actually use: us domestic modafinil modafinilxl.com/buy/modvigil-d… us domestic armodafinil modafinilxl.com/buy/waklert-do… not medical advice.

@punishedfounder @RealMattCase @1BioScience Bump up the AM or the PM to 10?

@RealMattCase @1BioScience bump up to 10g!

best way to waste your money. If you want something somewhat effective that is OTC consider things such as - PQQ - Huperzine A - cdp-choline or rosa rugosa

@punishedfounder You are crushing it. Ignore any commentary below that isn’t gratitude for the work you’re doing with this dope platform.

“I can buy [COMPOUND] for [MARGINALLY CHEAPER] than on peptaura” it just… might not be the [COMPOUND] and no guarantees no batch numbers no user-submitted COAs no financial leverage sounds like the move!

@patty_fi This is amazing.

I think people take way too many peptides This is all you need honestly BPC-157 TB-500 CJC-1295 Ipamorelin Tesamorelin Sermorelin GHK-Cu DSIP Epithalon Thymosin Alpha-1 PT-141 (Bremelanotide) Melanotan II AOD-9604 Fragment 176-191 GHRP-6 GHRP-2 Hexarelin Selank Semax LL-37 KPV Dihexa SS-31 (Elamipretide) MOTS-c Humanin Cerebrolysin Kisspeptin-10 GnRH (Gonadorelin) Oxytocin VIP (Vasoactive Intestinal Peptide) NAD+ Glutathione Pentosan Polysulfate Snap-8 Argireline Copper Peptides (GHK-Cu) Palmitoyl Pentapeptide Matrixyl Semaglutide Tirzepatide Retatrutide Survodutide Trenbolone​​​​​​​​​​​​​​​​ OxyContin

@MikeDBears34 This is why I have a space heater in my basement. 💪

Anybody else pull up to the gym at 5am, and just sit in the car, heat on full blast to the point of melting skin, contemplating all things life before mustering up the energy it takes to go smash leg day?

@BowTiedHRT S-tier list. Have 9 out of 10. 💪

🚨 THE PEPTIDES AND SUPPS THAT I REACH FOR THE MOST 🚨 Most of us chasing health and performance improvement can fall into the habit of throwing darts at a board full of trendy peptides while ignoring the handful that consistently deliver smooth, steady, results with favorable side-effect windows. After decades guiding clients through HRT, recovery, and performance protocols, the same short list surfaces repeatedly. These aren’t hyped up compounds. They are the ones that reliably shift energy, body composition, sleep architecture, recovery, and long-term resilience when dosed intelligently and layered on a dialed-in foundation. Here is the current lineup that have earned my repeated trust in practice (and two that I am beginning my personal research into): 1️⃣ HGH (Human Growth Hormone) 
The gold standard for body recomposition when levels are truly deficient or suboptimal. It drives lipolysis, supports lean tissue accrual, improves skin quality, and deepens sleep. Misjudging the dose or running it without proper bloodwork and glucose control can backfire so this is not a more is better type of compound. But in the right sweet spot, the positive results are unmistakable. 2️⃣ HCG (Human Chorionic Gonadotropin) 
Still the most reliable tool for preserving intratesticular testosterone and Leydig cell function during exogenous testosterone use. It prevents the full shutdown many assume is inevitable and helps maintain fertility and testicular volume. EOD dosing is my preferred dosing protocol versus twice weekly shots is far superior than twice a week or even less frequent administration, but like most of these compounds, everyone’s going to have a little bit of a different response and may require some fine-tuning. 3️⃣ DSIP (Delta Sleep-Inducing Peptide) 
An under appreciated peptide but profoundly useful for some clients struggling with fragmented sleep. It modulates stress response and improves deep sleep without the hangover of traditional sleep aids. The effect is subtle yet cumulative. I’ve been playing around with this one for the better part of the year and I like it more and more as the weeks and months pass. 4️⃣ MT2 (Melanotan II) 
Beyond the tanning effect, MT2 reliably boosts libido and erectile quality in many men, even when testosterone and estradiol are already dialed. Its mechanism involves MC4R stimulation. Go slowly with this one. MT2 is primarily a cosmetic peptide intended to provide a solid base tan with limited UV exposure but using too much too fast can leave you nauseous and flushed with a pesky boner: not a good combo. 5️⃣ Tirzepatide & Reta (Retatrutide)
 These dual and triple agonists have rewritten the book in very short order for fat loss and metabolic health. Both support appetite suppression, improved insulin sensitivity, and meaningful body fat reduction without the muscle wasting seen in older approaches. The key is slow titration, adequate protein, and resistance training to protect lean mass. Not everyone needs them, but for the right client they are transformative and I’m not afraid to say that, while not everyone needs them, these are most likely going to be in just about everyone’s longevity stack moving forward. 6️⃣ KLOW The marketing department at Peptide Central really missed the boat on this one. It should’ve been referred to as K-Glow to capitalize on the Korean beauty craze but alas. KLOW contains GHK-copper, TB 500, BP-157, and KPV. The stuff is legitimate magic for overall systemic reduction in inflammation and helping you heal up from not only the ravages of time, but also address acute soft tissue injuries quite well and quickly. 7️⃣ NMN & NAD+ 
These are foundational for improved cellular energy and mitochondrial function. Many of us notice steadier energy and better recovery when these are consistently supported, especially as we move past 40. 8️⃣ Shrooms 🍄 (Psilocybin micro or intentional macro; yep, I love them) 
I’ve been a huge proponent of psilocybin for decades and these are definitely a part of some protocols I build for clients wrestling with mood, perspective, or creative stagnation. When approached with respect and proper set and setting, the neuroplasticity window opens and this can accelerate meaningful personal shifts in mood, outlook, and creativity. 9️⃣ DIHEXA DIHEXA is a nootropic peptide that promotes synaptogenesis: the formation of new synaptic connections in the brain. It supports neuroplasticity, memory, focus, and cognitive resilience. Clients with brain fog or age-related mental slowdown have reported clearer thinking and sharper executive function once it takes effect. I have loved this one since the first day I tried it and continue to use it twice a week at 10 mg typically on Monday and Thursday. Some of my clients use it more often, some use it less often, but everybody seems to like the effect and it’s not something that you’re going to wonder whether or not you’re getting a benefit out of. Note: if you put yourself through some hard mental work while you’re taking the compound don’t be surprised if you’re exhausted by the evening. This stuff is leg day for the brain. 🔟 Methylene Blue 
Well known for cognitive support and mitochondrial efficiency. Low-dose protocols show promise for mental clarity and cellular respiration without the complexity of more exotic stacks. This is in my morning shake about 50% of days. Below are two additions currently earning strong client feedback and I certainly plan to integrate them thoughtfully as soon as I’ve gotten a few months of my own personal research into the compounds under my belt: 🔹 Pinealon: Targeted support for cognitive resilience and neuroprotection. Early reports suggest it helps with mental sharpness and stress buffering. 
🔹 Epitalon: The telomere and pineal support compound that continues to intrigue for longevity-oriented clients. Anecdotal improvements in sleep quality and recovery metrics make it worth monitoring closely. The common thread across all of these: they perform best when the basics are already handled. Get your testosterone, estradiol, thyroid, lipids, and inflammatory markers addressed first and sleep, training, and nutrition dialed in. Then layer peptides strategically rather than hoping they will rescue a shaky foundation. Chasing symptoms with peptides while ignoring the hypothalamic-pituitary axis, SHBG dynamics, or aromatization patterns is a fast track to self-imposed or practitioner-imposed misery. If you’re interested in experimenting with any of these compounds (but for the shrooms, you are on your own for procuring those), you can pick them up at Elite Research 🇺🇸 and get 10% off your order with Code 🪙🦊♌️ SFL10 🪙🦊♌️ eliteresearchusa.com/?code=SFL10 💭 MY PERSONAL TAKE WITH CLIENTS: 
I reach for this core group of research goodies far more often than the latest flavor-of-the-month because the risk-reward ratio stays favorable across a wide range of ages and goals. The goal is never maximal complexity. It is finding the minimal effective stack that creates a sweet spot where everything operates seamlessly: energy, recovery, body composition, mood, and drive all moving in the right direction without constant tweaking. Some clients can benefit from only one or two from this list. Others benefit from thoughtful personalized combinations. TL;DR: Focus on proven performers like HGH, HCG, Tirzepatide/Retatrutide, DSIP, MT2, and the cellular support duo of NMN/NAD+ before chasing every new peptide. Build the foundation first. Layer intelligently. Monitor relentlessly. ⭐️⭐️⭐️⭐️⭐️⭐️⭐️ I offer 1:1 holistic consultations for men and women serious about their health journey. We analyze your labs in the full context of your symptoms, goals, and lifestyle which allows us to build a unique roadmap that addresses what standard “normal” ranges often miss. We cover mitigation strategies, lifestyle levers, and precise adjustments to help you reclaim energy, performance, and long-term resilience. Ready to move beyond scattered protocols and generic advice? I am currently accepting new clients for in-depth 1:1 consultations. DM me to schedule your consultation. Let’s get to work on maximizing your recovery, your performance, and your full potential.

@auren skillz

AIs using the browser is insanely inefficient my colleague Nimna created a claude skill for cowork to make it 800% faster - and open sourcing it comment “skillz” here and i will get you to browser-optimizer skill kicker: it even reverse-engineers any web app's hidden API in under 2 minutes … extending claude’s chrome extension the problem: people will set up a sophisticated AI agent and then have it click through a web app one item at a time. like hiring a Formula 1 driver and making them push the car. every modern web app is a thin UI layer over an API. the data you want is one fetch() call away. but most people -- and most AI agents -- default to the human path: navigate, click, wait, read, repeat. the speed difference is NOT marginal. bulk API calls vs. manual page navigation is routinely 5-50x faster. i watched a workflow go from 2+ hours of manual clicking to 3 minutes by just intercepting the app's own API calls and reproducing them programmatically. It also includes workarounds for common blockers like PII filters on browser extensions, infinite scroll pages, and apps that use WebSockets instead of REST. the hierarchy is simple. if the app has a direct API, use it. if not, check if the data is already sitting in the browser's memory (most React and Next.js apps dump everything into window globals on page load). if not, open the network tab, click ONE thing, find the API pattern, then bulk-fetch everything. DOM scraping is the last resort, not the first instinct. this matters because AI agents are doing most of the repetitive work inside web apps. the agents that figure out the programmatic shortcut will be 10-50x more productive than the ones that simulate a human clicking around. same as how revenue per employee is about to go up 3-10x -- the gap between good and bad automation is enormous. manual clicking is the new manual data entry. it's a failure state NOT a strategy. (comment “skillz” here and i will get you to browser-optimizer skill)

@JayCampbell333 Big fan of your work @JayCampbell333. Do you have recommendations about where to source your favorite of these?

Whether you’re at 30,000 feet or in the middle of a packed schedule— your protocol stays locked in. People letting their travel schedule dictate their health. That’s backwards. Use the tools so your body stays resilient—no matter where you are. Stop letting inconvenience slow your progress. Grab the pen. Stay consistent. Own your results.

The Peptide Pen: Elite Performance, Anywhere ⬇️ Most people think being on a protocol means being tied to a fridge “I can’t travel with my vials.” “The syringes are a hassle.” “I’ll just start again when I get back.” No. That’s how you lose momentum. Optimization doesn’t take vacations. If you’re serious about your biology, your system has to move at the speed of your life. I travel with an insulin cooler loaded with peptide pens. No mess. No vials. No excuses. This is the next evolution of delivery. @daveasprey

@ElevateBiohack This is the best article on GH on all of X. 💪

Growth hormone sits in a unique category. It’s not a typical anabolic. It’s not a stimulant. It doesn’t flood your system and hammer you with side effects like some orals. But it’s easily one of the most transformative tools in both the performance and longevity space—if you understand how to actually use it. The catch? Most people don’t. They either use too little and expect overnight magic, or they go full tilt with massive doses thinking more is better—without having the lifestyle, diet, or support compounds to handle it. What you end up with is water retention, blood sugar issues, and disappointment. Not because GH doesn’t work, but because the strategy was wrong from the beginning. What makes GH so nuanced is that every dose range serves a different purpose. This isn’t like TRT where 150mg a week is going to more or less do the same thing across the board. With HGH, 1 IU and 8 IU are entirely different tools. You don’t take 3 IU and get “half the benefits” of someone using 6. You get a completely different hormonal response—and a different result. So let’s break this down in detail—real-world results, tradeoffs, and use-case logic behind each dosing range, from subtle longevity protocols to full-blown physique remodeling. No hype. No charts. Just honest breakdowns based on performance use, clinical insights, and biohacking data. elevatebiohacking.com/2025/06/24/ele…