Kepecs Lab

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Kepecs Lab

Kepecs Lab

@KepecsLab

St Louis, MO Bergabung Mayıs 2015
942 Mengikuti3.4K Pengikut
Kepecs Lab
Kepecs Lab@KepecsLab·
A backup lipolysis circuit to burn normally protected bone marrow fat without the normal adrenaline/noradrenaline stress pathway. Congrats to our collaborators on an elegant study.
Scheller Lab@schellerlab

Very happy to start 2026 by sharing our new manuscript in Nature Metabolism.✨ By studying the constitutive adipocytes in the bone marrow, we identified a brain-mediated pathway that bypasses the SNS to evoke massive fat loss. 🧠🦴 Full article here: lnkd.in/gH7eHv4r

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Peter H. Diamandis, MD
Peter H. Diamandis, MD@PeterDiamandis·
The science funding system is BROKEN. PhDs and professors are spending their days writing grant proposals rather than conducting research that could transform millions of lives. And the worst part? The system REWARDS predictable, safe, incremental science. It PUNISHES radical ideas and moonshots.
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Kepecs Lab
Kepecs Lab@KepecsLab·
@doristsao @AsteraInstitute Wow, that's a plot twist! Congratulations Doris, seems like an incredibly opportunity. Still thinking about what you showed at WashU a few months ago, some of the most exciting systems neuroscience results I’ve seen, can’t wait to see more!
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Doris Tsao
Doris Tsao@doristsao·
I am deeply excited to share that I will be joining @AsteraInstitute to start a new effort to understand how the brain generates consciousness and intelligence.
Astera Institute@AsteraInstitute

We’re launching Astera Neuro, a new neuroscience research effort led by @doristsao as Chief Scientist. Our aim is to unravel a profound scientific mystery: how the brain transforms sensory inputs into conscious experience. Advancing this work could illuminate the computational principles that drive perception and cognition and inspire approaches for neuroscience-informed AI research, potentially generating new pathways to AGI. Astera will support this work with $600M+ over the next decade. Read more: astera.org/neuroscientist…

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Paul Masset
Paul Masset@paul_masset·
I am recruiting graduate students for the experimental side of my lab @mcgillu for admission in Fall 2026! Get in touch if you're interested in how brain circuits implement distributed computation, including dopamine-based distributed RL and probabilistic representations.
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Kay M Tye PhD
Kay M Tye PhD@kaymtye·
Just reconnecting with @bjmarlin and… lo and behold… who can spot the two neuroscience glitterati enthusiastically photobombing?
Kay M Tye PhD tweet media
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Blake Richards
Blake Richards@tyrell_turing·
4/4) Keep your eyes out for what our Paradigms of Intelligence team will be producing in the coming years! I’m pumped about the work and I’m confident that this group will produce some major breakthroughs in the near future to make AI more efficient and robust. 🙂 🧠 🤖
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Liset M de la Prida
Liset M de la Prida@LMPrida·
Proud to take on this challenge: building the new @InstitutoCajal @CNC_CSIC @CINCnews into a space where neuroscience crosses boundaries and transforms how we understand the 🧠!! Honored to take the lead after @MoratallasLab and @JuanLerma1 @CSIC
Centro de Neurociencias Cajal - CSIC@CNCajal_CSIC

1/ 🧠 La neurocientífica 𝗟𝗶𝘀𝗲𝘁 𝗠𝗲𝗻é𝗻𝗱𝗲𝘇 𝗱𝗲 𝗹𝗮 𝗣𝗿𝗶𝗱𝗮 (@LMPrida) ha sido nombrada directora del nuevo 𝗖𝗲𝗻𝘁𝗿𝗼 𝗱𝗲 𝗡𝗲𝘂𝗿𝗼𝗰𝗶𝗲𝗻𝗰𝗶𝗮𝘀 𝗖𝗮𝗷𝗮𝗹 (𝗖𝗡𝗖) del @CSIC Su misión: lanzar un programa de investigación ambicioso y multidisciplinar.

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Kepecs Lab
Kepecs Lab@KepecsLab·
@cshperspectives Congrats, incredibly well deserved! Your work has transformed how science is shared 👏👏👏
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Kepecs Lab
Kepecs Lab@KepecsLab·
#ChatGPT5 is a letdown, not because it's not AGI, but because it's slow and then shy about discussing molecular biology "for safety reasons" Just canceled; Gemini's looking better
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab "correlation (science/notScience) to isRCT is pretty high?"
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Kording Lab 🦖
Kording Lab 🦖@KordingLab·
We can now define a set of rules of good science and automatically flag violations, and help users avoid violations. But we may kill creativity in the process. Which rules should we enshrine? How should we manage a system where some need rules and others are stifled by them?
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab you claim was in fact stronger, without RCT it's (almost) not even science: correlation (science/notScience) to isRCT is pretty high?
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Kording Lab 🦖
Kording Lab 🦖@KordingLab·
@KepecsLab Wait rct can be imporrant without being synonymous with good science.
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab happy you backtracked on the relevance of RCTs to science 😅😉
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab RCT != scientific rigor & in fact rigorous science has little to do with statistics
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Kording Lab 🦖
Kording Lab 🦖@KordingLab·
@KepecsLab Yes. Some people don’t randomize and compare a treated litter with another untreated litter :). But not sure what we may disagree on?
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab Not all randomized designs are RCTs. Not all controls are randomized. In fields where we can do experiments, we look for mechanisms not just through stats. And often the key isn’t what to do but what and how to ask
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Kording Lab 🦖
Kording Lab 🦖@KordingLab·
@KepecsLab I think the word just means a more to you than me. To me: randomized = assign is random. Controlled: there is treat and not treat. Trial: there is an intervention. So all your categories can be rcts to me.
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab RCTs are confirmatory, our experiments can be exploratory, observational, screens, and mechanistic, causal, computational etc... there is a BROAD range for how discovery happens
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab first, not all randomization is RCT, and RCTs are at best a narrow kind of causal inference without mechanistic insight
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Kording Lab 🦖
Kording Lab 🦖@KordingLab·
@KepecsLab as long as you don't want to make causal statements. Giving a bunch of random stimuli to an animal is an RCT!
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Kepecs Lab
Kepecs Lab@KepecsLab·
@KordingLab RCTs are to science what accounting is to mathematics
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Kording Lab 🦖
Kording Lab 🦖@KordingLab·
@KepecsLab correlation (science/notScience) to isRCT is pretty high? But kidding aside, probably half of science is RCT?
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Jelajahi

@doristsao @AsteraInstitute @mcgillu @ArminLak @OttTorben @GordFishell @bjmarlin @tyrell_turing