Alessandro Putzu

THE EFFECTS OF CYTOSORB® ON INFLAMMATORY MARKERS 🟰IL-6 🟰CRP 🟰Procalcitonin ⬆️Mortality Common financial conflicts of interest💰 Open access article: doi.org/10.1097/ccm.00… #CriticalCare #anesthesiology #EBM #cardiacsurgery 1/X

Dear friends and colleagues, It is with overwhelming sadness that we share news of the death of our colleague, mentor and friend, Rinaldo Bellomo. During recent days, both he and his family have received dedicated, expert and compassionate care from some of the finest in our ICU community. We share their pain and sense of loss. Over several decades, Rinaldo has made a profound and enduring impact on ICU practice in Australia, New Zealand and around the world. As a passionate researcher he challenged conventions, championed evidence-based practice in the care of the critically ill and supported countless colleagues in their research careers. As a compassionate mentor, colleague and friend, he touched and enriched numerous lives, and will be greatly missed. His loss will affect our whole community and in due course there will be opportunities to come together to celebrate his life. This will be a difficult time for many, but we know that our memories of Rinaldo’s relentless enthusiasm, warmth, optimism and boundless energy will help us all through the weeks ahead. In lieu of flowers, Rinaldo's family would welcome donations to support his research legacy at …lth-community-fundraising.raisely.com/inmem-rinaldo-… Our sincere condolences and best wishes go out to his family, friends and colleagues. Craig Carr, on behalf of the ANZICS community

Today, @ASMicrobiology retracted seven papers by Raoult and other authors @IHU_Marseille, all for breaches in human ethical research. The institute gave itself permission for dozens of studies, but did not get CPP permission, as is required in France. journals.asm.org/action/doSearc…

Look! We named all microorganisms we isolated from people in Africa (often without local permits) after our own institution or director! And then we wrote a paper about how many microbes are named after our own institution! 😬

The Effect of CytoSorb on Inflammatory Markers in Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials #XMed #AventhoAnestesia #AVENTHO #SMMCE ❌Sin evidencia de que funcione Los resultados no muestran disminución constante en IL-6 y otros parámetros inflamatorios en los primeros 5 días de tratamiento …d-ncbi-nlm-nih-gov.pbidi.unam.mx:2443/37607074/

For those not attending the @ESICM meeting in person next week, the sessions with new trial results will be streamed live. You can register here to watch them free: lives-stream.esicm.org/en/

@CritCareMed #CritCareMed @CritCareExplore

8/ ISSUES RCTs: small size, single center, risk of bias, conflict of interest, attrition, under-reporting Meta-analysis: heterogeneity in hyperinflammatory conditions, prophylactic (CV surgery) vs. therapeutic use, lack of individual patient data

THE EFFECTS OF CYTOSORB® ON INFLAMMATORY MARKERS 🟰IL-6 🟰CRP 🟰Procalcitonin ⬆️Mortality Common financial conflicts of interest💰 Open access article: doi.org/10.1097/ccm.00… #CriticalCare #anesthesiology #EBM #cardiacsurgery 1/X

this #KETAMINE article is still the most viewed ever of FRONTIERS IN ANESTHESIOLOGY 406,384 patients studied with surprising (?) results patients receiving perioperative ketamine (orthopedic surgery) later developed more psychiatric outcomes... frontiersin.org/articles/10.33…

We've just presented and published a multicenter RCT at #CCR23 and in @JAMA_current! Continuous vs Intermittent Meropenem Administration in Critically Ill Patients with Sepsis: The #MERCYtrial! 🔗 jamanetwork.com/journals/jama/… This 🧵 will explain the study in detail /11 #FOAMcc

“Why am I depressed?” Chiropractors: spine subluxation is the root cause! Naturopath: your body is full of toxins! Acupuncturist: your life energy is blocked! Homeopath: you need to balance your vital force! Reiki practitioner: unblock your chakras!

Do you remember THAM? We performed a systematic review, and THAM sure has a fascinating history. Strap in for a fun ride. 🧵 @MayoAnesthesia @RadosevichMisty @EricaWittwer @IARS_Journals journals.lww.com/anesthesia-ana… 1/?