CRI Mouse Genome Engineering Core at UTSW

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CRI Mouse Genome Engineering Core at UTSW

CRI Mouse Genome Engineering Core at UTSW

@CRI_TgCore

Mouse Genome Engineering Core @CRI_UTSW. We produce mouse models to support fundamental & translational research for scientists @UTSWNews & beyond.

Dallas Katılım Nisan 2020
197 Takip Edilen121 Takipçiler
CRI Mouse Genome Engineering Core at UTSW retweetledi
Hao Zhu Lab
Hao Zhu Lab@Zhu_Lab·
We are looking for a scientist to lead the CRI transgenic core. This is an opportunity to run a core AND to create a cutting-edge research program on in vivo gene editing. We've made > 200 new GEMMs since 2018, now we want to innovate! Please retweet cri.utsw.edu/facilities/mou…
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David R. Liu
David R. Liu@davidrliu·
Today we report in @NatureBiotech the development of dual-AAV in vivo delivery systems for prime editors that can support efficient prime editing in multiple organs such as brain, liver, and heart. 1/4
David R. Liu tweet media
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Hao Zhu Lab
Hao Zhu Lab@Zhu_Lab·
Somatic mutations accumulate in “normal” non-cancerous tissues (blood, skin, liver). But why are mutant clones selected? Do they merely proliferate more, selfishly? Or can clones adapt to disease? Could they protect tissues? We shed light on this: authors.elsevier.com/a/1gua9L7PXmc1- 1/10
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Lu Sun
Lu Sun@SunLab19·
With the amazing support from @CRI_TgCore Our postdoc fellows @ZhangTingxin @AksheevB work fearlessly in generating novel genetic reagents and discovering new mechanisms governing axon-oligodendrocyte communications
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CRI Mouse Genome Engineering Core at UTSW retweetledi
Feng Zhang
Feng Zhang@zhangf·
CRISPR technologies are powerful gene editing tools because they are programmable. We are excited to describe 3 new programmable systems, IscB, IsrB, and TnpB, some of the most abundant genes on the planet, with potential for gene editing. @ScienceMagazine science.org/doi/10.1126/sc…
Feng Zhang tweet media
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CRI Mouse Genome Engineering Core at UTSW
CRI Mouse Genome Engineering Core at UTSW@CRI_TgCore·
Pleasure to see that the lineage tracing lines generated by our core contributed to this beautiful work, discovering that the cells in zone 2 repopulate the liver" @YonglongW @Zhu_Lab
Hao Zhu Lab@Zhu_Lab

Excited to share our latest work on liver growth + regeneration. Diverse hepatocytes carry out distinct functions, but it is still unclear which ones are the source of new hepatocytes. Yonglong Wei discovered that cells in zone 2 repopulate the liver. science.sciencemag.org/content/371/65…

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Joshua Modell
Joshua Modell@jwmodell·
Just when you thought you knew everything about Cas9... Pleased to share our lab’s first paper, now online @CellCellPress: cell.com/cell/fulltext/…. We found Cas9 transcriptionally regulates its own promoter using a natural single-guide RNA. Kudos @reworkman0, @tejapammi et al.
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The Kohn Lab UCLA
The Kohn Lab UCLA@Kohn_Lab·
Join us tomorrow at Synthego’s #WorldCRISPRDay event. You will hear from experts like our mentor, Dr. Kohn, talk about #CRISPR ‘s role on cell and gene therapies. This is just one of many sessions that includes an ALL-STAR lineup of experts and pioneers. Registration is FREE.
Synthego@Synthego

Join us for the “CRISPR in Cell & Gene Therapies” session at #WorldCRISPRDay on 10/20 at 9am PDT. Tune in to hear experts in the field of cell & gene therapy talk about their latest #CRISPR research accelerating cell & gene therapies, from bench to clinic. hubs.ly/H0xLRbk0

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nature
nature@Nature·
It’s #CRISPR. Emmanuelle Charpentier and Jennifer Doudna ,who pioneered the revolutionary gene-editing technology, are the winners of this year’s #NobelPrize in Chemistry. #NobelPrize2020 go.nature.com/3jHfl68
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The Nobel Prize
The Nobel Prize@NobelPrize·
Congratulations to our newest #NobelPrize laureate Jennifer Doudna. From this picture we can imagine that she was happy to find out she had been awarded this year’s Chemistry Prize!
The Nobel Prize tweet media
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Keşfet

@LabJacks @davidrliu @NatureBiotech @ScienceMagazine @ScienceTM @SunLab19 @ZhangTingxin @AksheevB