Christopher Maher

Truly honored and grateful to be awarded the PCF Challenge Award with this incredible group of friends and collaborators + my super-⭐️ mentee @pradeep198212! Quite the team! @AOSartor @ChrisMaher_Lab @RPachynski @JakeOrmeMDPhD @flscientist Elisa Ledet

Interested to read the ins and outs of our Fast & Fair peer review experiment? Read the preprint at bit.ly/424d9x3 #fastandfairpeerreview

If you are interested in a Fast (7 days) and Fair peer review process consider this new initiative @BiologyOpen.

In memory of Dr. Felix Feng. Thank you @EUplatinum for honoring our beloved colleague and friend, gone too soon. We miss you Felix @MaryFengMD @nlinmd @PCF_Science sciencedirect.com/science/articl…

Cover 🤗…congrats to the whole team! 🎉 @aadel_chaudhuri @ChrisMaher_Lab @sartor_oliver @ChadTangMD @WashUOncology @SitemanCenter @WashUDeptMed @MayoClinic @MDAndersonNews @PCF_Science @Pachynski_Lab

Felix was the best of us. I'm heartbroken by his passing.💔His spirit of generosity, kindness, humility, his humor, intelligence & scientific acumen - you made us better scientists & better people, Felix. Love & miss you always. My deepest condolences to @MaryFengMD & family.🙏♥️

The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts.

Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in lethal prostate cancer Out on @CCR_AACR Study investigates metastatic castration-resistant #ProstateCancer (mCRPC) resistant to androgen receptor signaling inhibitors (ARSIs), a highly lethal form of @cancer . Using targeted and genome-wide cell-free DNA sequencing from 126 and 43 mCRPC patients, respectively, researchers found that AR/enhancer alterations in cell-free DNA🧬 prior to ARSI treatment correlated with significantly worse PFS and OS Further analysis of the plasma methylome revealed increased promoter-level hypomethylation in patients with these alterations. Additionally, transcription factor analysis suggested that cancer lethality is driven by increased stemness. This stem-like signature was validated in a separate cohort, establishing AR/enhancer alterations as a prognostic biomarker for lethal mCRPC. aacrjournals.org/clincancerres/… @pradeep198212 @RBabbra @SydneyCaputo @flscientist @ChadTangMD @RPachynski @OJSartor @ChrisMaher_Lab @aadel_chaudhuri @MayoRadOnc @MayoCancerCare @MayoClinic @TulaneMedicine @MDAndersonNews @WashUOnc

Great collaborative effort!!! Awesome job @pradeep198212

Portrait unveiling at the conclusion of the John F DiPersio Immunotherapy Symposium @WashUOnc @SitemanCenter @WUDeptMedicine @WUSTLmed @BarnesJewish @WUSTLdbbs @WashUDPS #bmtsm #celltherapy #cartcells #leusm #lymsm #mmsm #mdssm

Congrats Dr. Zhao!!!

Excited to share our collaborative work with @felixfengmd @David_A_Quigley using #scRNA-Seq to study the #lncRNA landscape in metastatic castration resistant #prostate #cancer Read at npj Genomic Medicine rdcu.be/dApls @WashUOnc @SitemanCenter @PCF_Science @WUSTLmed

@Kaochar2 @AACR @CR_AACR @BCMDeptMedicine @BCMCancerCenter Congrats!

Honored to receive this recognition from @AACR @CR_AACR @BCMDeptMedicine @BCMCancerCenter

@JoshLangMD @PCF_Science Congratulations Josh!

Truly humbled to receive this recognition in honor of Claire Bothwell who championed research as she battled cancer herself. A project that began with a patient asking why his #prostatecancer changed and could we find it earlier and easier. jci.org/articles/view/… @PCF_Science

@ResearchWyatt @HsiehLab @piet_ost @NatureCancer @ewarner_ubc @kim_vdeecken @MurthaAj @EdmondMKwan @cherberts1 @VanProstateCtr @UBCmedicine @BCCancer_GSC @PCF_Science @VCHResearch Congrats Alex, great work!!!

Our latest study with @piet_ost, of whole prostates, lymph nodes, and ctDNA at initial diagnosis in de novo metastatic prostate cancer (distant mets) is out in @NatureCancer: rdcu.be/du8Tu. 1/n thread 👇

New in NAR Cancer. A resource to guide functional studies: a compendium of long noncoding RNAs associated with tumor, immune, or stromal cells in pancreatic cancer. From @ChrisMaher and coworkers. @WUSTL @SitemanCenter #lncrnas #bioinformatics. academic.oup.com/narcancer/arti…

@HsiehLab @BellodiLab Gave a great talk @ keystone today!

Want to see more of his work @BellodiLab? He will be at Keystone next week! https://199.231.141.162/index.cfm?e=Web.Meeting.Flyer&MeetingID=2058

It is great when you get a chance to invite a friend to talk at your institution. I met @BellodiCristian of @BellodiLab when we were postdocs @RuggeroDavide lab. My bench was right next to his. Learned much of what I know about mol biology from just being next to him.

Great to see this collaborative work with @aadel_chaudhuri and @RPachynski online now!

@winhide Have a collaborator needing to do just this!

Excited to share our collaborative work with Ryan Fields and Li Ding Single-cell transcriptomics reveals long #noncoding #RNAs associated with tumor biology and the microenvironment in #pancreatic #cancer academic.oup.com/narcancer/arti… @WashUOnc @SitemanCenter @WUSTLmed