Coller Lab

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Coller Lab

Coller Lab

@CollerLab

The Coller Lab uses modern approaches to investigate #quiescence, cell cycle control, #autophagy, and #cancer. Official account managed by the lab members.

UCLA Katılım Kasım 2021
184 Takip Edilen124 Takipçiler
Coller Lab
Coller Lab@CollerLab·
We are so happy that Michael Cheng, a former undergraduate researcher in the lab and now a bioinformatics graduate student at @UCLA , will be defending his thesis this week (Wednesday at 1 pm; in person and on zoom). All the best, Michael!
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Shyam Prabhakar Lab
Shyam Prabhakar Lab@shyam_lab·
Years ago we tried to model cancer-associated fibroblast (CAF) subtypes in vitro, but gave up because only the proliferative subtype survived culture (duh!). This study could change all that: Perturb-seq with CRISPRa of 1,836 TFs induces diverse fibroblast states in vitro(!). 👏
Anirban Maitra@Aiims1742

Fantastic work by @thenormanlab in @NatureGenet Recreating fibroblast diversity in vitro by activating transcription factors Demonstration of the power of CRISPRa Perturb-Seq to deregulate TF expression in fibroblasts (Function!) nature.com/articles/s4158… nature.com/articles/s4158…

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UCLA Jonsson Comprehensive Cancer Center
UCLA Jonsson Comprehensive Cancer Center@UCLAHealthJCCC·
Dr. Hilary Coller (@CollerLab) discussed her latest research on how epigenetic patterns can predict cancer outcomes more accurately than traditional markers. Her pan-cancer model reveals targetable epifactors across five tumor types. Watch the talk here: bit.ly/4jEAMTU
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Coller Lab
Coller Lab@CollerLab·
Kaiser is going to defend this doctoral thesis next week (Thursday, February 27th) at 9 AM in 158 Hershey Hall. Everyone is welcome to attend.
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Molecular Cell
Molecular Cell@MolecularCell·
In this review for our focus issue on patterns in molecular biology, @LuLaboratory explores how metabolites and metabolic enzymes regulate chromatin and histone modification patterns, highlighting the crosstalk between the metabolome and the epigenome. cell.com/molecular-cell…
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Roman Barth
Roman Barth@RomanBarth2·
CTCF stall DNA 🧬 loop ➰ extrusion by cohesin - but exactly how it pulls this off is a 'mechanistic mystery' (to cite @Anders_S_Hansen , Nucleus, 2020). We just preprinted 📜 a new study @biorxivpreprint that provides some answers to this enigma: tinyurl.com/3r2a4ux2
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Coller Lab
Coller Lab@CollerLab·
Congratulations to our graduate student, Kaiser, on his amazing talk at the MCDB retreat. Woot woot 🎉
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Coller Lab
Coller Lab@CollerLab·
Congratulations to our undergraduate student, Namita, on her excellent presentation to the Biomedical Research Minor! Great job Namita !
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Coller Lab
Coller Lab@CollerLab·
Congratulations to our undergraduate student, Maya Rhee-Pizano, on being accepted into the CARE Fellows Program!! Great job Maya!
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Keşfet

@UCLA @biorxiv @lab_paredes @jernst98 @emukamel @CEpigenomics @bpasaniuc @biorxiv_cellbio