Damien Collison

Residual angina after PCI is common. The explanation depends on the interaction between microvascular dysfunction and the epicardial disease pattern 🎯 Focal CAD: successful PCI unmasks coexisting CMD. 〰️ Diffuse CAD: persistent epicardial resistance remains the dominant cause. Impact of Coronary Microvascular Dysfunction on Patient-Reported Symptoms After PCI | jacc.org/doi/10.1016/j.… @crfheart @PCRonline @AbbottNews @bouissetfred #PCI #CoronaryPhysiology #CMD #PPG

First time at #EuroPCR @PCRonline a dedicated Physiology Course. Physiology is becoming available in every case—#CCTCA, angio or invasive. Understanding the fundamentals is key to interpretation and decision-making. FFR is not only an index; it is a concept. Join us on Monday 18 in Paris. #Physiology #FFR Don't miss it pcronline.com/Courses/EuroPC…

FAME 2 long-term just published in @NatureMedicine Stable CAD with FFR ≤0.80: FFR-guided PCI + MT vs MT alone ↓ death/MI/urgent revasc (33.6% vs 41.3%, win ratio 1.25, NNT~17)—mainly ↓ urgent revasc (10.1% vs 25.2%). nature.com/articles/s4159… At 10+ yrs Physiology still matters -> My digital avatar explains it all 🎥🤖 👇 @crfheart @TCTMD @PCRonline @AbbottNews @Heartflow @JACCJournals #FFR #PCI #StableCAD

Just published Thanks and congratulations to all the co-authors @JEscaned @ziadalinyc @divaka_perera @AntonioMariaLe2 @sbrugaletta @PCRonline @crfheart @CircAHA @BernardBruyne @fredericbouisse @DamienCollison

Kicking off #TCT2025 on Saturday morning, we will present the 1 year clinical outcomes of patients treated with PCI in Focal vs Diffuse disease #PPG Physiology will become more clinically relevant than ever before 💪🏻

PPCI 2025 @PPCImeeting underway in Leeds with a thought-provoking keynote lecture by @ncurzen. Thanks to all sponsors and @MillbrookMed to make this happen - looking forward to the rest of the talks @krishnaraj82 @SameerKurmani @DamienCollison @LabsLtht

Preview the #PPCI2025 programme ahead of tomorrow! Highlights include a keynote lecture on PPCI after 55 by @ncurzen, case discussions from Leeds General Infirmary, hands-on sessions and debates on whether it’s time to rethink aspirin and beta-blockers, plus much more! #PPCI

🔊2 weeks to go to INOCA 2025! 📍London SE1 7AR @TheBHF @NIHRresearch Incredible international faculty How to sessions Guideline updates Informative talks Debates Live cases Lived experience Innovations in INOCA ‼️Register ASAP millbrook-events.co.uk/event/INOCA202…

Outstanding work! 👏 This is the first randomized study comparing resting and hyperemic pullbacks. 🔑 Key finding: Both resting (iFR) and hyperemic (FFR) pullbacks are equally influenced by lesion cross-talk. ✅ This settles a long-standing debate in the physiology field.

This first randomized comparison of FFR & iFR in serial #cvCAD shows that both FFR & iFR pullbacks overestimate hemodynamic benefits of #PCI. Post-PCI physiology should be routinely performed in diffuse & serial disease. jacc.org/doi/10.1016/j.… @divaka_perera @mattlkw #JACCINT

🚨FFR and iFR systematically overestimate the result of PCI in serial and diffuse coronary disease 🚨 #CoronaryPhysiology 🎲Randomised 👁️Blinded 🙋‍♀️Within patient comparison 🔗 Full link @JACCJournals jacc.org/doi/10.1016/j.… 📺Watch our summary below👇

Rapid exclusion of coronary microvascular dysfunction with novel contrast-derived indices of coronary microvascular function. A potential clinically useful, cost-saving method of testing @DamienCollison @_RobSykes @conor1366 @DanielTYAng @ColinBerryMD ahajrnls.org/4m46PPq

1 week left to register for The Physiology Course (28–29 April) 50% OFF: 5 tickets for Physicians – Code: PHYSIO50OFFER 10 tickets for Fellows – Code: PHYSIO50FELLOWOFFER Don't miss this opportunity & join the physiology of the future! registration.physiologycourse-be25.com/tpc25 @CoreAalst

Thought-provoking new analysis from the FLAVOUR trial by Zhang et al this week. Should PCI be guided by intracoronary physiology or by intacoronary imaging? Do we need the best of both worlds? Thanks to @JACCJournals for the invitation to comment. shorturl.at/dyGuT

🚨 Tomorrow is the day! The 1st PPG Summit kicks off in just 24 hours! ⏳ Don’t miss out on this exclusive opportunity to hear all about PPG from leading experts in coronary physiology! 🗓 Thursday 12th December 2024 ⏰ Time: 3:00 PM CET 🇪🇺 | 11:00 PM JST 🇯🇵 | 9:00 AM EST 🇺🇸 | 6:00 AM PST 🇺🇸 📋 It’s your final chance to register and join the live stream summit tomorrow – a must-attend for anyone in the cardiovascular field! Register NOW – Last chance to secure your spot! 👉 registration.coreaalstplatform.com/coreaalst/regi… @ColletCarlos @BernardBruyne @DrAllenJ @ziadalinyc @divaka_perera @MortonKern @DamienCollison #PPG #PPGSummit #CoronaryPhysiology #HeartHealth #MedicalInnovation

Thanks @Heart_BMJ ! Abnormal coronary microvascular function is associated with increased epicardial atherosclerotic plaque burden. Could this be the link between CMD and increased MACE in #INOCA?@TomJFord @DavidCarrick14 @DamienCollison @ColinBerryMD heart.bmj.com/content/early/…

🚨 Free Remote Registration is OPEN for the 1st PPG Summit! 🚨 🎥 Don’t miss the chance to join the live stream hosted by leading coronary physiology experts! Thursday 12th December 2024 ⏰3PM CET 🇪🇺 | 11PM JST 🇯🇵 | 9AM EST 🇺🇸 | 6AM PST 🇺🇸 🔎 Check out the full agenda below for a glimpse of the valuable sessions and speakers! 📌 Register NOW – This opportunity is too important to miss 👉 registration.coreaalstplatform.com/coreaalst/regi… @ColletCarlos @BernardBruyne @DrAllenJ @ziadalinyc @divaka_perera @MortonKern @DamienCollison #PPG #PPGSummit #CoronaryPhysiology #HeartHealth #MedicalInnovation

Each week in the Physiology Masterclass series, we’re revealing how coronary physiology is driving better patient outcomes. 💙 In this week’s episode, we’re tackling the issue of post-PCI symptoms: why do one in four patients remain symptomatic after the procedure? Dr. Carlos Collet @ColletCarlos has the answers. Stay tuned for his episode dropping later this week! 👀 Have you experienced this challenge? Comment below! Catch the previous episode here: coreaalstplatform.com/coreaalst/modu… @EmanueleBarba13 @SimoneBiscaglia @sbrugaletta @BernardBruyne @jeroen_sonck @CardioAalst @OLVZaalst #PhysiologyMasterclass #Cardiology #FocalDisease #DiffuseDisease

#OriginalResearch: Pullback pressure gradient derived from FFR pullback is a physiologic measurement of diffuse vs focal coronary stenosis and predicts improvement in coronary flow post-PCI ahajournals.org/doi/10.1161/CI…

Fifty years since Gould's seminal work on coronary autoregulation, we are honoured to contribute with the first proof of coronary autoregulation in humans. nejm.org/doi/full/10.10… This advances our understanding of coronary physiology significantly. @NEJM @BernardBruyne