Deepan Thiruppathy

Fish, Frogs, Friends, Lend me your Ears. 🐟🐸🐁🦎 Read this 'Behind the paper' story from @MathiThiru95 about her PhD work with @CrumpLab: thenode.biologists.com/fish-frogs-fri… #DevBio #EvoDevo

It is finally out! Muntathar Al-Shimary, Doudna Lab, @bradyfcress and I present a gene knockdown tool that works in diverse phages: CRISPRi through antisense RNA Targeting (CRISPRi-ART)! Check out the final paper in @NatureMicrobiol nature.com/articles/s4156…

The outer ear is a mammalian innovation but where did it come from? In our study in @Nature, @MathiThiru95 and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. nature.com/articles/s4158… 1/n

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @DjenetBousbaine led the charge... @Nature 1/55

Our latest preprint is out! This paper led by @SukhwanYoon uncovers a new process controlling the global hydrogen and nitrogen cycles, i.e. the direct coupling of hydrogen oxidation and ammonification. A beautiful combination of isolation, bioreactor, and systems biology studies.

Behold SkinCom!!!! Exciting new avenue of translational microbiome research in the Karsten Zengler lab led by @asama_lekbua and @Deep_Thirup now out in @CellRepMethods—@f_askarian and @armin_kousha from our group helped establish the in vivo model cell.com/cell-reports-m…

Many thanks to fellow authors @asama_lekbua, Joanna Coker, @f_askarian @armin_kousha @lisa55asil, Sherlyn Weng, Amber Hauw, @victornizet and Karsten Zengler. 😁🙌🏾

Presenting SkinCom! A 9-member synthetic bacterial community that includes anaerobic and aerobic members of the skin. Great for testing cosmetics, with strong agreement with human trial results! And, can recover RNA and ribosome footprints for multiomics! #skin #microbiome

Day 3 of the lab retreat- Cenotes and Maya ruins 🇲🇽

In our new paper at Cell (@CellCellPress), we reveal secrets of how the third form of life, archaea, make energy. We uncover new lineages of hydrogen-using enzymes, both minimal and complex. These help archaea thrive in all sorts of extreme environments. sciencedirect.com/science/articl…

@Zipcar So you still charge people a late fee when your disruption was the reason why they couldn't start, continue and/or complete their trip on time?? Because that's ridiculous and shows you take no ownership for your actions. As a member from 4 years, this is very disappointing.

We're hiring! We are seeking an exceptional postdoc associate to help us work on solving the antibiotic resistance crisis, details and apply here: broadinstitute.avature.net/en_US/careers/…

Reproducible #microbiome research of the skin 💪🏽🦠🌍 #skincareproducts #skinmicrobiome #metagenomics

How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…

DOE GSP PI Meeting 2024

The Singapore Sting: Why an activist published a fake paper on ‘LGBTQ+ child acceptance.’ retractionwatch.com/2024/01/17/the…

Our paper is out today in @Nature! Imagine getting this plot when studying single-cell data of growing bacteria! Could it be the cell cycle?! We found that a gene’s response to its replication reveals gene regulation on a genomic scale. nature.com/articles/s4158… @AndrewPountain

The only reason to care about #DaylightSavingTime is when you started a growth curve assay before the change, so now you need to remember to add that note about the change when taking the next time point to get the right growth rates. 🦠⏱️ #Microbiology

@ben_a_adler @doudna_lab @bradyfcress Congrats Ben! 🙌

I’m really excited to share our new pre-print “Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi”, with co-first author Muntathar Al-Shimary @doudna_lab and the newly-minted @bradyfcress lab! biorxiv.org/content/10.110… 🧵🧵 1/

@Chloe_Lieng Stick a needle in and make everyone crave cotton candy! 😆🍭

Caramelised fructose anyone?