Sophie Dumont

Excited to share our work out in @CurrentBiology today! We find that NuMA acts as a spindle "glue" - independent of its partner dynein. Congrats to student Nathan Cho who led the work, and thanks to Merve, Aryan and @Yildiz_Lab for in vitro help. cell.com/current-biolog…

Excited to share NuMA preprint #2/2! We report structural and functional insights into how NuMA activates and regulates dynein at cell division. Congrats to Merve Aslan @Yildiz_Lab, @AmicoEnnio @Carter_Lab and Nathan Cho from our lab. And others inc. Maddie Blaauw from our lab. biorxiv.org/content/10.110…

Excited to share NuMA preprint #1/2! We find that NuMA mechanically reinforces the spindle independently of its partner dynein. Congrats to student Nathan Cho who led the work, with Merve Aslan and @Yildiz_Lab. biorxiv.org/content/10.110…

@alexandraflong Alex was a postdoc with Tim @StearnsLab & Jessica Feldman

Congrats to Alexandra Long @alexandraflong, the second student from our lab to start their own lab! Her lab is in Univ. Kentucky's Biology Dept, studying the evolutionary cell biology & biophysics of cellular organization. Check it out! alonglab.org

Excited to share our work out in @CurrentBiology ! We find that SKAP's binding to microtubules *reduces* friction at the kinetochore-microtubule interface and increases attachment stability under force. Congrats to postdoc Miquel @RosasSalvans and all authors! With @Caleb_J_Rux and Moumita Das. sciencedirect.com/science/articl…

Nominate a colleague or yourself for the Motility and Cytoskeleton Early Career Award at the 2025 Biophysical Society Meeting! To do so fill out this form and email Radhika Subramanian and I your CVs by Dec 1 2024: docs.google.com/forms/d/e/1FAI…

Christina was a postdoc with Alex Dunn @Dunn_Lab. And wrote a book with Rob Phillips, The Restless Cell: Continuum Theories of Living Matter. Wow ...

Congrats to Christina Hueschen @clhueschen, the first student from our lab to start their own lab! Her lab is in UCSD's Cell & Dev Bio Dept, studying the physical biology of parasites. Can't wait to see what science they do. Check it out! hueschenlab.biosci.ucsd.edu

@MullinsLab @JTenthorey @UCSF @UCSFMedicine @UCSFcmp Congrats Jeannette!!!

Congratulations to CMP Assistant Professor Jeannette Tenthorey (@JTenthorey) for receiving the NIH Director's New Innovator (DP2) Award! @UCSF @UCSFMedicine @UCSFcmp

With this work we are sad to say goodbye to postdoc Miquel @RosasSalvans who is returning to Barcelona. We will miss Miquel's intellect, generous spirit, and all the fun times doing science together. Best of luck!

Excited to share a preprint! We find that SKAP's binding to microtubules *reduces* friction at the kinetochore-microtubule interface and increases attachment stability under force. Congrats to postdoc Miquel @RosasSalvans and all authors! With @Caleb_J_Rux and Moumita Das. biorxiv.org/content/10.110…

@ScienceyRosalie @RobertoZoncu @MarquseeLab @MullinsLab @MartinUCSF @TheHurleyLab @DJuliusSF @JTenthorey @dsboothacosta Congratulations to you both and have fun!!! 🤩

More soon, but for now a HUGE thank you to the village who made this journey to PI-hood possible: amazing mentors Peter Walter, @RobertoZoncu, @MarquseeLab , @MullinsLab , @MartinUCSF , @TheHurleyLab , @DumontLab , @DJuliusSF , @JTenthorey, @dsboothacosta and many others...

At the interface of cell biology, biochemistry, and structure, the lab will leverage allosteric and functional genomic tools to define how stress response signaling rewires cellular metabolism, including in highly specialized glial cells in the brain.

Nominate a colleague or yourself to speak at the Motility & Cytoskeleton Subgroup at the 2025 Biophysical Society Meeting! Radhika Subramanian and I are organizing the subgroup and looking for nominations by July 8th: forms.gle/i3AMosmEugx2cn….

Excited to share our work @JCellBiol! We find that torques within and outside the spindle oppose each other to limit spindle twist during anaphase. Congrats to @LilaNeahring who led the work! Thanks to Nathan Cho, @Caleb_J_Rux, @Yildiz_Lab, Upadhyayula and Subramanian Labs. rupress.org/jcb/article/22…

Excited to share our work @JCellBiol! We find that chromosome size-dependent spindle forces impair mammalian mitotic error correction of long chromosomes. Congrats to graduate student @megan_chong who led this work! With Miquel @RosasSalvans @VannaTran5 rupress.org/jcb/article/22…

Excited to share our work out in @PLOSONE with @goga_lab showing that expressing an oncogene protects spindle poles from fracturing in mechanically confined environments. Congrats to first authors @RenaldoSutanto and @LilaNeahring and all authors! journals.plos.org/plosone/articl…

@MEmilieTerret @alexpersat @LennonLab @NordenLab @DMVlab @Mech_Morph_Lab @SchnorrerL @AnneStraube @maitrejl @Franze_Lab @ManuelTHERY @MincLab @RongLabOfficial @WickstromLab @StefanDiezLab @LecuitThomas @gomes @RouxLab Thank you all for organizing, it was a wonderful conference!

Thanks @alexpersat @LennonLab @NordenLab @DMVlab @Mech_Morph_Lab @SchnorrerL @AnneStraube @maitrejl @Franze_Lab @ManuelTHERY @MincLab @RongLabOfficial @WickstromLab @StefanDiezLab @DumontLab @LecuitThomas @gomes @RouxLab, Keren, Voituriez, Zaidel-Bar for sharing your science

@JonathanAKuhn Congrats, Jon!!

New paper out in Biorxiv! Big thanks to my collaborators and labmates!

Congratulations to graduate student @megan_chong from our lab who received a UCSF Dean’s Award for Excellence in Mentoring! Megan is an inspiring mentor to many in our lab and out. And congrats to all other awardees! @UCSFGradDiv