Francesco Neri
200 posts
Francesco Neri
@FrancescoNeri_
NeuroAge Therapeutics | Buck Institute for Research on Aging
San Francisco Katılım Ocak 2021
370 Takip Edilen553 Takipçiler
PS: Works best on desktop. On mobile, rotate your screen to avoid squished plots.
English
I started building a dashboard that allows exploration of the aging/longevity biotech landscape using data from agingbiotech.info/companies.
You can try it here:
📊 f-neri.github.io/lbi
If you have ideas on what additional data or views would make this more useful, let me know!
English
Francesco Neri retweetledi
Federal funding for US biomedical research is moribund.
Since October 1 2025, NIH is -80% in new grants and -70% in values (total dollars).
Labs are closing down and researchers are leaving science.
To what end?
English
Francesco Neri retweetledi
Loyal has raised a $100M Series C from age1, Baillie Gifford, existing investors, & more
this brings Loyal's total funding to over a quarter of a billion dollars
we are building the longevity pharma, starting with dog longevity. thanks @FastCompany for the exclusive ->
English
Whoof!
Celine Halioua@celinehalioua
our dog longevity drug LOY-002 has earned FDA safety approval we now have 2 of 3 major sections of our New Animal Drug Application complete (!) if (when) we earn FDA manufacturing approval, Loyal will launch the *first FDA-approved lifespan extension drug*
San Francisco, CA 🇺🇸 English
Francesco Neri retweetledi
The first pivotal, FDA-enabling clinical trial of a longevity drug is now fully enrolled
We will monitor these dogs for the next ~4 years, quantifying millions of data points across biological changes, quality of life, disease, + lifespan
Loyal@loyalfordogs
1,300+ dogs. 72 clinics. One giant leap toward the first FDA-approved lifespan extension drug for dogs. The STAY study is fully enrolled!
English
Francesco Neri retweetledi
I had a great time catching up with @mkaeberlein in Seattle and recording an episode on the @OptispanPodcast.
Brain Aging & Alzheimer’s Prevention: The Future of Cognitive Health Testing | Dr. Christin Glorioso
Watch on YouTube👇
youtu.be/y1JUCTBxW6s?si…
YouTube
English
Francesco Neri retweetledi
The Buck is proud to host upcoming Longevity Summit 2024, featuring leaders across biotech, pharma, investment, research to advance aging interventions and drive innovation in longevity industry. Register: lnkd.in/gx8Q8mYT
@Longevitygl #LongevitySummit2024
English
Any recommendations for US-based CROs for preclinical rodent experiments?
English
Francesco Neri retweetledi
Announcing AgingBiotech.info/companies version 2.0,
a giant overhaul & update:
- new columns
- 50+ new companies
- 200 companies fully up-to-date as of 2024 inc. all of the most noteworthy
- a new non-alphabetical default ordering based on rough significance (more on this below)
...
English
Francesco Neri retweetledi
Can we use CRISPR screens to identify genes that drive neural stem cell aging?
Super excited to see this work published @Nature!
Huge congrats to Tyson @ruetz_tyson, Angie Pogson, @kashiwagi_chloe, and all authors! Great collaboration with @MCBassik!
nature.com/articles/s4158…
English
Francesco Neri retweetledi
BioAge is now a public company! I'm incredibly proud of our team and grateful to our partners and investors who made this possible. By targeting the biology of aging, we're developing therapies to tackle metabolic diseases and change lives. Excited for what's ahead!
BioAge@bioagelabs
We are thrilled to announce the closing of BioAge's IPO! As of September 26, we are trading on Nasdaq as $BIOA. This milestone will enable our development of novel therapies that treat metabolic diseases by harnessing the biology of aging. (1/3)
English
Francesco Neri retweetledi
Short report: The state of the mitochondria portion of the aging biotech field:
50 companies!
$1.4+B raised
700+ people
150+ clinical trials
many MoAs/targets:
mitophagy, transplant, fission, NAD+, UrolithinA, CD38, PINK1, PPARδ, DRP1, USP30, Complex 1, OMA1, & more
Read on:
English
Francesco Neri retweetledi
Anyone who cares about longevity science should read the @A4Li proposal "A New National Institute for Longevity and Aging Research (NILAR)" . It's a start toward much needed reform at NIH. I've signed the petition and encourage you to do so as well: a4li.org/support-nilar/
English
Francesco Neri retweetledi
Breakdown and quick thoughts on today's IL11 lifespan paper from @AA_Widjaja, @StuartaCook1 et al, mainly from an #AgingBiology perspective with a dash of #DrugDevelopment... 1/n
Nature Portfolio@NaturePortfolio
A paper in @Nature reports the ageing effects of a pro-inflammatory protein called IL11 in mice. Inhibition of this protein is shown to improve the health of old mice and increase their lifespan. go.nature.com/3WqC0JX
English
Francesco Neri retweetledi
📢New Open🔓Access Paper
A Fully-Automated Senescence Test (FAST) for the high-throughput quantification of senescence-associated markers by Francesco Neri (@FrancescoNeri_), Judith Campisi & Akos A. Gerencser et al.
rdcu.be/dLZMe
#CellularSenescence #aging #highcontentimageanalysis #highthroughputscreening #senescence #machinelearning @BuckInstitute
English
It has been a long journey, and I couldn't have done it without the support of other Campisi lab members and the student community at Buck. I'm extremely thankful to Judy for everything she taught me about senescence, aging, and striving to do good science
English
Francesco Neri retweetledi
Announcing: AgingBiotech.info/therapeutics (beta)
a table of most available (potential) aging therapeutics: supplements, drugs, lifestyle, etc.
The goal isn't to judge or rank them but to summarize other evaluations & link useful sources of details.
Important notes: 🧵
English