Michalis Georgiou, MD, PhD

After 6 years of med school and 4 years of ophthalmology research, intern year, a PhD, 40+ papers, 400+ citations, 3 countries and 2 continents, it’s real. Let me examine your eyes 👀 #ophthalmology #residency #medtwitter

@VavvasRetina @drrishisingh @JohnBMillerMD The best team! 👁️

With our new Chair @drrishisingh, Associate Fellowship Director @JohnBMillerMD at the retina wet lab course for trainees run by our own Dr. Lizzy Rossin with participation of many faculty and VR fellows.

Ophthalmological manifestations in a cohort of Cowden syndrome patients in a large tertiary healthcare system What this study adds · In a large U.S. tertiary system (Mass General Brigham), the observed CS prevalence was 1.28 per 100,000— somewhat higher than other prior population-based estimates. · Among 77 confirmed CS patients, only 17 (22%) underwent ophthalmologic evaluation, and 4 patients (≈24% of those examined; 5% of the cohort) had ocular findings potentially related to CS. Visual acuity was mostly excellent and stable over a median ophthalmic follow-up of 4.5 years in this cohort · Potential CS-related ocular findings included retinal hamartomas, an eyelid capillary hemangioma, a trichilemmoma, and a stable peripapillary hamartoma-like lesion/old CNVM. Only one patient had complete multimodal retinal imaging (OCT, FA, OCTA), underscoring limited ophthalmic documentation and the need for standardized eye screening in CS. · Three of the four patients with ocular findings carried truncating PTEN variants, hinting at a possible genotype association that warrants larger, prospective studies. · No distinct ocular phenotype emerged from the cohort plus literature synthesis, reinforcing calls for multicentre prospective work to define ocular risk and screening guidelines in CS. #Cowden @HMSeye #retina #PTEN

Next-generation phenotyping of inherited retinal diseases: Eye2Gene (AI-driven algorithm). Better-than-expert accuracy for 63 common genetic causes. @ucl @npontikos @GeoMichalis @MaximilianPfau3 @sktywagner @riksag @KonBalaskas #NIH @NatMachIntell: brnw.ch/21wUfkJ

Excited to see advancements in retinal research for X-linked retinitis pigmentosa. The community urges Johnson & Johnson to seek approval for its XLRP gene therapy, offering hope to patients. fightingblindness.org/news/retinal-r… @MichelMichaelid @UCL_Retina

Happy #RareDiseaseDay2025! 👁️🧬 Let's make this another unbelievable year of discovery for rare eye diseases! @MariyaMoosajee @MichelMichaelid @cm_stanton @neeru_vallabh @KarkStaphonsen @GeoMichalis @HeonJeon #Ophthalmology #IRD #MedTwitter #ophthalmicgenetics #genetherapy

🗞️🚨I am incredibly grateful and humbled to be a part of this remarkable team @MichelMichaelid @UCL_Retina that delivered such a meaningful project. It has truly been life-changing and has had a positive impact on the children and their families. lnkd.in/dfVn6v8T

Pleasure to see our PDE6A study feature at @AAOjournal @MichelMichaelid

New Publication @ARVOiovs 👁️ We expand on our previous work on CNGA3-Achromatopsia, longitudinally assessing the foveal cone mosaic preservation with adaptive optics. Kudos to Mohamed and the whole team! @UCL_Retina @AOIPLab @MichelMichaelid iovs.arvojournals.org/article.aspx?a…

It is an honor to host Joseph Carroll, PhD, Richard O. Shultz, MD & Ruth Works Professor in Ophthalmology from @MedicalCollege as the Dastgheib Pioneer Award in Ocular Innovation distinguished lecturer.

@AOIPLab @dukeeyecenter @MedicalCollege @SabanLab Well Deserved! Great to see you Joe! @AOIPLab

@dukeeyecenter @MedicalCollege The honor was mine! I had an amazing visit-great to see some old friends (including @GeoMichalis and @SabanLab and many Twitter-less peeps) and meet some new ones. Food scene in Durham is pretty stellar!!

New in Ophthalmology Retina, our comprehensive analysis of PDE6A-retinopathy. @MichelMichaelid leading and an amazing team of co-authors. This study details the natural history of PDE6A-retinopathy in one of the largest cohort to date. sciencedirect.com/science/articl…

New @AJOphthalmology 🚨🧬👁️ Peer review data of one of the most promising trials in IRDs. Proud to be among an amazing group of collaborators! @MichelMichaelid @UCLeye @Moorfields Safe and well-tolerated, and showed improvements in efficacy assessments. ajo.com/article/S0002-…

Case report 🦄. Diagnosed RP in a patient with albinism, now confirmed for PDE6A-RP and TYR-albinism. Age-matched controls included. Out at AJO Case Reports. #RetinitisPigmentosa #Albinism #Genetics 👁️@MichelMichaelid Link: sciencedirect.com/science/articl…

Ophthalmology Advocacy Day: Team Arkansas advocating for access to quality eye care, safety, research funding, and a sustainable profession. 👁️ @eyeadvocacy @aao_ophth #myf2024 #Advocacy #EyeCare #ResearchFunding #Arkansas

@KarkStaphonsen @dukeeyecenter @RamMaldonado32 Always kind Kirk! Look forward, a lot to learn!

@GeoMichalis Unstoppable force in IRD! Watch out @dukeeyecenter @RamMaldonado32

New Publication Alert! Retinal structure in CSNB is stationary and no specific genotype - structure correlates were identified. VA appears to be relatively stable, with rare instances of progression. @MichelMichaelid @tacguimaraes sciencedirect.com/science/articl…

Great pleasure to see our comprehensive review out! @MichelMichaelid

PRER article from @MichelMichaelid and collaborators who provide expert insight into genetics and imaging of photoreceptor degeneration #RetinaAwarenessMonth #retina #RP @MoorfieldsBRC @UCLeye @Wills_Eye featureshttps://www.sciencedirect.com/science/article/pii/S1350946224000090

We report the genetic findings, clinical spectrum and natural history of Best vitelliform macular dystrophy (BVMD) in a cohort of 222 children and adults. @MichelMichaelid @Moorfields @UCL_Retina Kudos to Yannik Laich and an amazing group of co-authors!

Fresh off the press @AJOphthalmology our comprehensive analysis of PDE6B-retinopathy. @MichelMichaelid , Shaima Hashem and an amazing team of co-authors. This study details the natural history of PDE6B-retinopathy in one of the largest cohort to date. ajo.com/article/S0002-…