Guoping Li

Congrats to my postdoc Dr. Tian Hao for presenting our work on cardioprotective roles of an ischemia-induced tRNA-derived RNA (#tDRs) at #AHA25 and the pre-symposium hosted by ACRE and CNAHA (won YIA award 2nd place)! Exciting progress in understanding tDRs in cardiac protection.

In a new study, researchers from @MGHanesthesia and colleagues found a protective kidney RNA that could transform disease treatment. The study was published in @ScienceMagazine. Read more: massgeneralbrigham.org/en/about/newsr… science.org/doi/10.1126/sc… @SaumyaDas_Lab @GuopingLi2

Our @ScienceMagazine paper is out! Discovered how tRNA-derived small RNA (tsRNA/tDR) protects kidneys via RNA autophagy. science.org/doi/10.1126/sc… Huge thanks to @SaumyaDas_Lab and all our amazing collaborators! Excited for the therapeutic potential ahead! @MGHanesthesia @mghcvrc

The new August #JCTR issue is welcoming this 2024 September with 23 articles..link.springer.com/journal/12265/… a🧵to know the 3 top accessed ones 👇@ELaraPezzi #ISCTR @FudimMarat @pjrbarton @JSluijter @SolovevaAnzhela @GuopingLi2 @roddywalsh @LauraIop_UNIPD @SmartNicola @SpringerNat

Excited to share our latest paper in Circulation @CircAHA! We introduced an inhalation method for delivering exosomes to treat heart injuries, aiming to offer a noninvasive option for patients with MI. Congratulations @junlangli! Full article: doi.org/10.1161/CIRCUL…

Delighted to attend and present at #RNATx2024 @RTI_UMassChan our work on tRNA derived small RNAs and their role in kidney disease, led by @GuopingLi2 with many collaborators. Some robust discussion on defining mechanisms and designing therapeutics.

🔥 Hiring a funded postdoctoral fellow position in human genetics! Come join us @CGM_MGH @broadinstitute @harvardmed! 🔥 Apply: partners.taleo.net/careersection/…

How can one non-invasively sample the transcriptome of organs like the heart. Our study now published in @CircAHA shows the mapping of differentially expressed transcripts in HFpEF and HFrEF mapping to different cardiac cell-types. ahajournals.org/eprint/KAIQX6T…

@SaumyaDas_Lab @mghcvrc Thanks a million for your mentorship and support. Hope we can translate this tRNA-derived small RNA into beneficial therapeutics.

4 years of hard work led by Dr. Guoping Li to develop tools to manipulate tDR expression and careful studies to understand the mechanistic link between tDR and cellular response to injury. Now poised as possible new therapeutics! @GuopingLi2 @mghcvrc

The Cardiovascular Performance Program @MassGeneralNews has been at the forefront of sports cardiology since 2009. Our fellowship has generated over a dozen sports cardiologists across N. America. Please RT & encourage your brightest to apply for '25-'26! bit.ly/3VmPfv2

We are hiring to fill Research Tech positions. Ideal candidates are graduating seniors looking to gain 2+ years of immersive research experience related to the development and application of genome editing tech. Details can be found on our lab website: kleinstiverlab.org/open-positions

Wang & colleagues found that #exercise protected against #Doxorubicin-induced #cardiotoxicity by regulating an important #Bcell inhibitory receptor. Learn more at ahajrnls.org/4c82iq9 @PilarAlcaidePhD @HImmoLehmann @Guopingli2 @sjtu1896

🚨 @StanfordEndo is hiring! 🚨 We are seeking TWO physician-scientists or scientists in any area of endocrinology, diabetes or metabolism. PhD, MD, and MD/PhD applicants are all welcome. Apply below to join a collaborative and nurturing environment. Plus lots of sunshine! ☀️🌴

Moving forward discovering 2 more 2023 highly commented papers in #JCTR link.springer.com/article/10.100… #ISCTR @ELaraPezzi @FudimMarat @pjrbarton @JSluijter @SolovevaAnzhela @GuopingLi2 @roddywalsh @LauraIop_UNIPD @SmartNicola @SpringerNature

Happy Lunar New Year! 🧧 🧨🏮 新年快樂 #YearOfTheDragon 🐉

Check out our recent paper in @embojournal describing novel connection between #autophagy, #NAD metabolism and #Mitochondria. Another layer of cellular nutrient sensing linking autophagy with regulation of the NAD degrading enzyme NNMT. @CharlesMBrenner embopress.org/doi/full/10.10…

#JCTR special issue "New insights into the Genetics of Cardiomyopathies: read the highlights by Guest Editor @roddywalsh 👇👇👇#ISCTR @ELaraPezzi @FudimMarat @pjrbarton @JSluijter @jozinetm @SolovevaAnzhela @SluimerJudith @GuopingLi2 @LauraIop_UNIPD @SmartNicola

Very pleasant experience of moderating the session of “EV biogenesis and functions” at #AAEV2023. Really enjoyed the 10 fascinating talks with new discoveries in EV research!

Glad to discuss with Paul Schimmel/Bernhard Kuhle on the exciting era of 'tRNA renovatio'-a rebirth of tRNA function through fragmentation and tsRNA biogenesis @MolecularCell. Many directions to explore on both basic & translational fronts!#tRNA #smallRNA🎇cell.com/molecular-cell…

For anyone interested in EV research, including new technologies, therapeutics, biomarkers, AAEV 2023 is the meeting to be at. A great line up of speakers, including > 30 young investigators. Check it out and sign up!aaev.org