Heidi Huang

@Biotech2k1 🐁

My open post. I haven't done one of these in a long time as you get 100 spam replies as soon as you do. I only let people I follow reply to post to avoid the bots and spam. If you want me to follow you so you can reply to my posts, just comment here and I will follow you.

Game Arena from @generalityinc is the largest LLM strategy game tournament to date. Games are great for measuring LLMs on instruction following, long-horizon planning, and problem-solving. In fact, models that are Olympiad-level at math and coding often struggle to make accurate moves in Game Arena (median illegal-move rate: 11.4%). Game environments also resist contamination and saturation: every run is unique, so there’s no risk of training-data leakage, and the bar keeps rising as models improve. Game Arena has digitized hundreds of board games into fresh new environments, and today it’s debuting its first tournament, with models like GPT-5 High, Claude Opus 4.1, and DeepSeek V3.1 from OpenAI, Anthropic, Qwen, DeepSeek, Google, and more going head-to-head. You can watch game replays and full model reasonings on game-arena.ai. Congrats on the launch, @sanerc110 and @kaylalee278!

excited to write about biology as a part of this group!

Cas9 gets an upgrade! Check out our new paper in The CRISPR Journal: bit.ly/hiNLS-Cas9 Eric Noel (who is on the job market!) created Cas9 constructs w/ nuclear localization signals (NLS) in the backbone, boosting genome editing activity in T cells. #CRISPR

This amazing post by @an1lam captures the essence of why biotech feels (and is) slow, and how operating with a sense of urgency can have compounding benefits. asimov.press/p/fast-feedbac…

Meet the 2025 TIME Fellows. This new cohort is already: 🧠 Investigating brain aging & resilience 🧪 Advancing immune + genome repair 📊 Building tools for molecular biomarker discovery 🎙️ Driving science storytelling & startup ideas They are the future of #agingbiology.

@RuxandraTeslo @open_phil @slatestarcodex @WorksInProgMag @IFP @AsteraInstitute also tech stories often center on charismatic ppl making bold decisions, which creates compelling narratives ppl can imagine themselves in. biotech breakthroughs involve teams working within institutional constraints, so the stories seem less cool / personally resonant imo

@open_phil @slatestarcodex @WorksInProgMag @IFP @AsteraInstitute And interestingly, it's often tech ppl who are interested in the founding myths of biotech! How it emerged, its history, its key players, why it's regulated the way it is. Meanwhile, there's vast amounts of info about all this, in the heads of 70 yr

I was talking about someone abt the different cultures in tech vs biotech. Tech seems much more optimistic abt the possibility for change/ doing things in a new way. @arcinstitute was financed by a tech CEO. All the progress stuff w/

@RuxandraTeslo @open_phil @slatestarcodex @WorksInProgMag @IFP @AsteraInstitute tech innovations move from concept to product more quickly, so the connection btwn origin story and outcome is clearer. biotech breakthroughs involve decades of incremental progress across institutions, so the story is less accessible and harder to extract clear lessons from

@ElliotHershberg @mfgrp Congrats Elliot!

I’ve been busy this week… 👀 Passed my PhD defense! Insanely grateful for @mfgrp. Truly epic scientist and human.

30 Essays to Make You Love Biology Day 3. "Seven Wonders," by the great Lewis Thomas. "I decided to try making a list, not for the magazine's dinner party but for this occasion: seven things I wonder about the most." Number 2 on the list: Bacteria that survive in 250°C waters.

What if we could universally recombine, insert, delete, or invert any two pieces of DNA? In back-to-back @Nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design

How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…

@KINGGRAINT #jazzhop the chillest of vibes youtu.be/uKzMJk4-wMY

Who’s got some new music I could listen to?

@EveryApplePro Dude the ceramic shield is supposed to be on the SCREEN not on the GLASS back. But I doubt the ceramic shield makes a big difference in the level of protection it offers to the screen. What happened to the screen in the drop test?

iPhone 12 vs 12 Pro Drop Test! Ceramic Shield IS 'The toughest glass in any smartphone'. youtu.be/fQc2jW_A3ik

@lofizone Wait what happened??

@spotifyartists A small amount of plays, but it’s Taipei, Taiwan in #1 followed by Montréal and then Moscow :)

Which city do you have the most listeners in? 👀

@lofizone Check this out! open.spotify.com/track/7ARq1orX…

@lofizone soundcloud.com/seizmikmusic/r…

@lofizone open.spotify.com/album/0kw40SQe…

@WeAreNovation Oops totally forgot about that. Thanks for the correction!

@seizmikmusic All of our Launchpads come bundled with Ableton Live 10 Lite, samples and plug-ins – everything that you need to get started.