Paul Ogongo

388 posts

Paul Ogongo

Paul Ogongo

@JaTcells

Human immunity. Infectious diseases. T-cells. Mycobacterium tuberculosis. Helen Hay Whitney Foundation Fellow.

Katılım Şubat 2015
416 Takip Edilen437 Takipçiler
Paul Ogongo
Paul Ogongo@JaTcells·
FINALLY OUT: We describe a set of Mtb antigens that preferentially induce Th17 cells against Mtb infection. Th17 cells are associated with contained Mtb infection in humans and animal models of TB, suggesting a protective role. insight.jci.org/articles/view/…
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Paul Ogongo
Paul Ogongo@JaTcells·
IN PRESS: Using Metaclonotypist, we discover dominant immune response to TB driven by a public HLA-associated TCR metaclonotypes. This work opens avenues for biomarker and Mtb antigen discovery for TB vaccine. nature.com/articles/s4146…
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Paul Ogongo retweetledi
Daniel Barber, PhD
Daniel Barber, PhD@danielleobarber·
We still don’t understand how T cells control tuberculosis. Our new paper shows that Mtb-specific T cells in NHP and human lung granulomas make many interesting effector molecules upon TCR stimulation. There’s a whole lot more to T cells in TB than IFNγ! cell.com/iscience/fullt…
Daniel Barber, PhD tweet media
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Working Group on New TB Vaccines
Working Group on New TB Vaccines@newtbvaccines·
Join the #WGNV ECR Network - Virtual Coffee Corner on 4 December 2025 to network, share experiences, and talk about #TBvaccine activities of interest. 📅Date: Thur 4 Dec 2025 🕑Time: 9:00 am EDT / 3:00pm CET | 4:00pm SAST | 7:30 pm IST 🔗tinyurl.com/kj7kuuft
Working Group on New TB Vaccines tweet media
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Science Advancement and Outreach
In the study, Owen Leddy and colleagues used human phagocytic cells to map TB peptides that activate CD4+ T cells, a key immune defense. Guided by this, they designed mRNA immunogens that dramatically improved antigen presentation, offering a promising path toward an effective TB vaccine. 👥 @TheBrysonLab, @JaTcells, @Qingyun_Liu, @HeyuanMNi, et al. 🏛️ @ragoninstitute, @MITdeptofBE, @kochinstitute, @UCSF_EXPM, @UNC_SOM, @AHRI_ETH 💰 @theNCI, @NIAIDNews, @NIH_NIEHS 📘 @ScienceTM: science.org/doi/10.1126/sc…
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Paul Ogongo
Paul Ogongo@JaTcells·
Join us at the ECR Coffee Corner at the @newtbvaccines on Nov 6 2025. Looking forward to reconnecting this Early Career Researchers in Tuberculosis.
Working Group on New TB Vaccines@newtbvaccines

Join the #WGNV ECR Network - Virtual Coffee Corner on 6 November 2025 to network, share experiences, and talk about #TBvaccine activities of interest. 📅Date: Thur 6 Nov 2025 🕑Time: 9:00 am EDT / 3:00pm CET | 4:00pm SAST | 7:30 pm IST 🔗Register at tinyurl.com/ra6jv6en

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Paul Ogongo
Paul Ogongo@JaTcells·
NEW Study: Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants’ Full-Length Spikes in a Multiplex Luminex Assay mdpi.com/3501064 #mdpiviruses via @VirusesMDPI
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Paul Ogongo
Paul Ogongo@JaTcells·
New Study: We report the dysregulation of CD4 T cell responses by Type 2 Diabetes in people with TB. Increased circulating Th17 cell subsets and altered CD4 maturation and differentiation. Potential explanation for high risk for TB in those with T2D frontiersin.org/journals/immun…
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Babak Javid
Babak Javid@javid_lab·
Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages biorxiv.org/content/10.110…
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The Immunology in Africa Podcast
The fifth episode in our #TBImmunologySeries ft. @AneleGela, a Research Officer at @satvi_uct, @UCT_news , where he studies host determinants of protective immunity against #tuberculosis. #Immunology #Vaccines #TB #Tuberculosis #SciComm #GlobalHealth #PublicHealth #Immunity
The Immunology in Africa Podcast tweet media
The Immunology in Africa Podcast@immunoafrica_

Launching April ending, our #TBImmunologySeries features leading scientists whose work cut across TB prevention, diagnosis, treatment, and vaccine development. #tuberculosis #TB #immunology #immuneresponses #vaccines #globalhealth #immunesystem

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